Diabetes: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide among diabetologists, endocrinologists, and nutritionists in understanding and treating diabetes. The book covers, in a single volume, the science of oxidative stress in diabetes and the potentially therapeutic use of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes such as apoptosis, cell signaling, receptor-mediated responses and more. This approach recognizes that diseases are usually multifactorial and that oxidative stress is a single component of this.
Pharmacological treatments for diabetes are commonly marked by unwanted side effects, leading to treatment efforts using naturally occurring substances. But a plant-based approach alone is not sufficient; understanding the processes inherent in the oxidative stress of diabetes is vital for clinical workers, dietitians, and nutritionists.
This translational work provides that understanding. The book begins by covering the basic biology of oxidative stress from molecular biology to imaging in relation to diabetes. There are chapters on neuropathy, nephropathy, atherosclerosis, cardiomyopathy, and retinopathy. The book then moves on to antioxidants in foods, including plants, components of the diet, and their relevance to diabetes.
- Nutritionists will use the information related to mitochondrial oxidative stress in one disease and propose new diet-related strategies to prevent such conditions arising in another unrelated disease.
- Dietitians will prescribe new foods or diets containing antioxidants for conditions that are refractory by conventional pharmacological treatments.
- Dietitians, after learning about the basic biology of oxidative stress, will be able to suggest new treatments to their multidisciplinary teams.
- Nutritionists and dietitians will learn about cell signaling and will be able to suggest preventive or therapeutic strategies with antioxidant-rich foods to reduce damage done by diseases involving abnormal cell signaling.
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- Oxidative stress in diabetic nephropathy
- Oxidative stress in diabetic atherosclerosis
- Diabetic stroke and oxidative stress
- Diabetic cardiomyopathy and oxidative stress
- Oxidative stress in diabetic retinopathy
- Beta glucan and neuroprotection in diabetes
- Selenium and diabetic peripheral neuropathy
- Neuropathy and micronutrients supplementation
- Nigella sativa oil, diabetic neuropathy and oxidative stress
- Diabetic nephropathy, propolis and oxidative stress
- Green tea, oxidative stress and diabetic nephropathy
- Diabetic nephropathy and tocotrienol
- Resveratrol, diabetic nephropathy and oxidative stress
- Anti-RAGE compounds, atherosclerosis and diabetes
- Vitamin E and vascular protection in diabetes
- Ginkgo biloba, atherosclerosis protection in diabetes
- Zinc supplementation and oxidative stress of vascular tissues
- Taurine and cardiac oxidative stress
- Statins, diabetic oxidative stress and vascular tissue
- Herbal Chrysanthemi Flos, oxidative damage and diabetic vascular protection
- Antioxidant supplements and diabetic retinopathy
- Neuroprotective lutein in the retina
- Anti-oxidant related micronutrients and diabetic retinopathy
- Resveratrol, oxidative stress and diabetic liver
- Pomegranate juice, oxidative stress and the lung in diabetes
- Rosemary extract in diabetes
- Antioxidative effects of allium cepa in diabetes
- Citrus flavonoids and oxidative stress in diabetes
- Oxidative stress, diabetes and iron
Gingseng, diabetes and oxidative stress
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London.
Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.