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Xenopus Development

  • ID: 2674200
  • Book
  • 424 Pages
  • John Wiley and Sons Ltd
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Frogs from the genus Xenopus have long been used as model organisms in basic and biomedical research. These frogs have helped unlock key fundamental developmental and cellular processes that have led to important scientific breakthroughs and have had practical application in embryology, cancer research and regenerative medicine. Xenopus Development is a vital resource on the biology and development of these key model organisms, and will be a great tool to researchers using these frogs in various disciplines of
biological science.

Xenopus Development is divided into four sections, the first three highlight key processes in Xenopus development from embryo to metamophosis. These sections focus on the cellular processes, organogenesis and embryo development. The final section highlights novel techniques and approaches
being used in Xenopus research.

Providing thorough and detailed coverage, Xenopus Development, will be a timely and welcome volume for those working in cell and molecular biology, genetics, developmental biology and biomedical research.

Provides broad overview of the developmental biology of both Xenopus laevis and Xenopus tropicalis
Explores cellular to systems development in key biomedical model organisms
Timely synthesis of the field of Xenopus biology
Highlights key biomedical and basic biological findings unlocked by Xenopus

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Contributors vii

Preface ix

Section I Oocyte and Early Embryo 1

1 Transcription in the Xenopus Oocyte Nucleus 3Joseph G. Gall

2 RNA Localization during Oogenesis in Xenopus laevis 16James O. Deshler

3 From Oocyte to Fertilizable Egg: Regulated mRNA Translation and the Control of Maternal Gene Expression 38Chad E. Cragle & Angus M. MacNicol

4 Polarity of Xenopus Oocytes and Early Embryos 60Malgorzata Kloc

5 Germ–Cell Specification in Xenopus 75Mary Lou King

Section II Midblastula Transition, Gastrulation, and Neurulation 101

6 The Xenopus Embryo as a Model System to Study Asymmetric Furrowing in Vertebrate Epithelial Cells 103Jacek Z. Kubiak, Isabelle Chartrain, & Jean–Pierre Tassan

7 Induction and Differentiation of the Xenopus Ciliated Embryonic Epidermis 112Marie Cibois, Pierluigi Scerbo, Virginie Thomé, Andrea Pasini, & Laurent Kodjabachian

8 Wnt Signaling during Early Xenopus Development 130François Fagotto

9 Neural Tube Closure in Xenopus 163Hitoshi Morita, Makoto Suzuki, & Naoto Ueno

Section III Metamorphosis and Organogenesis 187

10 Primordial Germ Cell Migration 189Aliaksandr Dzementsei & Tomas Pieler

11 Development of Gonads, Sex Determination, and Sex Reversal in Xenopus 199Rafa³ P. Piprek & Jacek Z. Kubiak

12 The Xenopus Pronephros: A Kidney Model Making Leaps toward Understanding Tubule Development 215Rachel K. Miller, Moonsup Lee, & Pierre D. McCrea

13 Development of Neural Tissues in Xenopus laevis 239William A. Muñoz, Amy K. Sater, & Pierre D. McCrea

14 The Development of the Immune System in Xenopus 264Louis Du Pasquier

15 Neural Regeneration in Xenopus Tadpoles during Metamorphosis 293Mauricio Moreno, Karina Tapia, & Juan Larrain

Section IV Novel Techniques and Approaches 309

16 Atomic Force Microscopy Imaging of Xenopus laevis Oocyte Plasma Membrane 311Francesco Orsini

17 Size Scaling of Subcellular Organelles and Structures in Xenopus laevis and Xenopus tropicalis 325Lisa J. Edens & Daniel L. Levy

18 A Model for Retinal Regeneration in Xenopus 346Masasuke Araki

19 The Xenopus Model for Regeneration Research 368Ying Chen & Gufa Lin

20 Genomics and Genome Engineering in Xenopus 383Léna Vouillot, Aurore Thélie, Thibault Scalvenzi, & Nicolas Pollet

Index 403

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Malgorzata Kloc
Jacek Z. Kubiak
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