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UICC Manual of Clinical Oncology. 9th Edition

  • ID: 3048751
  • Book
  • 856 Pages
  • John Wiley and Sons Ltd
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The Manual of Clinical Oncology, Ninth Edition, published with the International Union Against Cancer (UICC), provides a concise, accessible and feasible reference covering state of art multidisciplinary clinical oncology in order to meet the needs of clinicians caring for cancer patients throughout the world.

Edited by world–renowned practising oncologists and written by key opinion leaders, this book contains authoritative and up–to–date information on cancer detection, diagnosis and treatment alongside topics such as survivorship, special populations and palliative care.

Remodelled and revised for the ninth edition to provide practical information to oncology workers, the UICC Manual of Clinical Oncology is structured in two parts. Part 1 covers general principles of cancer diagnosis and management with additional attention to special settings in oncology, including supportive care and survivorship, and Part 2 covers site–specific multidisciplinary cancer management. The edition includes up–to–date summaries of all treatment modalities (medical, surgical and radiation) for all tumour sites. It also contains the latest TNM classifications outlined in the TNM Classification of Malignant Tumours.

The ninth edition includes:

Practical presentation with bullet points, tables, and flow charts intended to facilitate quick reference for day–to–day clinical practice in busy oncology environments,
Representation of multidisciplinary care for site specific management,
Evidence–based approaches to management, including specific treatment recommendations and investigations guided by clinical practice guidelines,
State of art evidence–based recommendations that take into consideration the lack of availability of certain medications or resources, as well as practice variations, in different and remote regions of the world, and
Contemporary topics on cancer treatment, such as cancer informatics, evidence levels, principles of prognostication, survivorship and cancer in pregnancy.

Oncologists, oncologists–in–training, nurses working with cancer patients and other health professionals responsible for treating and caring for those with cancers will find the UICC Manual of Clinical Oncology an indispensable and comprehensive resource.

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Foreword x

Preface xi

About the Editors xiii

Contributors xvi

PART 1 General principles of cancer diagnosis and management 1

Principles of knowledge generation and translation

1 Cancer epidemiology 3

2 Levels of evidence, guidelines and standards 12

3 Prognosis and classification of cancer 23

4 Principles of cancer staging 34

5 Assessment of treatment outcome 40

6 Cancer informatics 53

Principles of cancer diagnosis

7 Imaging 63

8 Pathology 83

Principles of treatment

9 Principles of surgery 98

10 Principles of radiotherapy 108

11 Principles of systemic therapy 124

Special settings, supportive care and survivorship

12 Treatment in pregnancy 134

13 Treatment in the elderly 139

14 Oncology emergencies 145

15 Supportive care during curative treatment 155

16 Pain management in cancer 168

17 Palliative care 174

18 Survivorship 184

19 Rehabilitation 194

PART 2 Site–specific multidisciplinary cancer management 203

Thoracic malignancies

20 Lung 205


21 Breast 221

Gastrointestinal malignancies

22 Liver 241

23 Biliary tract and pancreas 263

23.1 Biliary tract 263

23.2 Pancreas 270

24 Oesophagus 280

25 Stomach 297

26 Colon, rectum and anus 308

26.1 Colon and rectum 308

26.2 Anus 327

Genitourinary malignancies

27 Prostate 333

28 Bladder and other urothelium 343

29 Kidney 354

30 Testicular germ cell tumours 368

31 Penis 384

Haematological malignancies

32 Lymphoma 392

33 Myeloma 415

34 Leukaemia 427

Gynaecological cancers

35 Cervix 449

36 Uterus 467

37 Ovary and fallopian tube 479

Head and neck cancer

39 General principles of head and neck cancer management 503

40 Nasopharynx 512

41 Oral cavity 524

42 Larynx and hypopharynx 542

43 Oropharynx 559

44 Major salivary glands 571

45 Nasal cavity and paranasal sinus 586

46 Head and neck unknown primary 597

Endocrine tumors

47 Pituitary 609

48 Thyroid 626

49 Adrenal tumours 641

50 Neuroendocrine tumours 656

Dermatological cancer

51 Skin: Basal cell carcinoma, squamous cell carcinoma and Merkel cell carcinoma 674

52 Melanoma 689

Central nervous system and ocular cancers

53 Central nervous system 706

54 Eye: Choroidal melanoma, retinoblastoma, ocular adnexal lymph


55 Bone (osteosarcoma) 745

56 Soft tissue 754

Childhood malignancies

57 Paediatric tumors 768

Specific cancer situations

58 Cancer of unknown primary (no 59 HIV and transplant–related neoplasms 797

59.1 HIV–related neoplasms 797

59.2 Post–transplantation lymphoproliferative disease 809

59.3 Cancer following solid organ transplantation 812

Index 815

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Shao Hui Huang
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