Systems Biology in Toxicology and Environmental Health is an essential reference for undergraduate students, graduate students, and researchers looking for an introduction in the use of systems biology approaches to assess environmental exposures and their impacts on human health.
- Provides the first reference of its kind, demonstrating the application of systems biology in environmental health and toxicology- Includes introductions to the diverse fields of molecular and cellular biology, toxicology, and computational biology- Presents a foundation that helps users understand the connections between the environment and health effects, and the biological mechanisms that link them
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Chapter 2: Biology basics
Chapter 3: From the genome to epigenome: fundamental concepts
Chapter 4: Tools and technologies used in systems biology
Chapter 5: Environmental contaminants
Chapter 7: Environmental contaminants, inflammation-associated pathways and disease
Chapter 8: Environmental contaminants, apoptosis-associated pathways and disease
Chapter 9: Environmental contaminants, DNA damage and repair pathways and disease
Chapter 10: Environmental contaminants and hormone response and disease
Chapter 11: The systems perspective
Dr. Rebecca Fry is an Associate Professor in the Department of Environmental Sciences and Engineering at the Gillings School of Global Public Health at UNC-Chapel Hill. She also holds appointments in the Curriculum in Toxicology and the Lineberger Cancer Center. She is the Deputy Director of UNC's Superfund Research Program funded by the National Institute of Environmental Health Sciences (NIEHS). She also serves as the Director of Graduate Studies in the Curriculum of Toxicology and Co-PI of an NIEHS-funded T32 training grant. Dr. Fry received her B.S. in Biology from William Smith College. She received her M.S. and Ph.D. in Biology from Tulane University and completed her post-doctoral training at MIT. Her research focuses on unraveling the biological mechanisms by which prenatal exposures to toxic metals impact infant health. A primary goal of Dr. Fry's research is to increase awareness of the deleterious impacts of exposures during the prenatal period and to improve public health initiatives to address this issue.