Postgraduate Haematology. 7th Edition

  • ID: 3387152
  • Book
  • 952 Pages
  • John Wiley and Sons Ltd
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This comprehensive textbook is the key resource for postgraduate trainees or residents in haematology. Now in its seventh edition, the book continues to provide everything the reader needs for examination preparation or clinical practice.

Postgraduate Haematology discusses up–to–date knowledge of the pathogenesis, clinical and laboratory features, management and treatment of a wide range of blood and bone marrow disorders in a concise and user friendly style. It presents essential information for everyday use and teaching, as well more detailed scientific background for more in–depth reading, accompanied by thoughtful referencing. 

The clearly illustrated full–colour figures and charts demonstrate key facts, and are supplemented by numerous high quality photomicrographs of blood cells and tissues. Over 51 chapters from international authors, including the WHO Classification of Haematopoietic and Lymphoid Tissues, Postgraduate Haematology provides an expert review of malignant and non–malignant haematology.

  • New sections reflect advances in the specialty, e.g. knowledge gained from new generation sequencing, latest anticoagulant drugs, diagnostic laboratory tools, and treatment strategies
  • Superb four–color illustrations and photomicrographs of blood cells and tissues throughout
  • Includes algorithms to aid with decision–making for treatment
  • Companion website featuring figures and tables from the book

Arm yourself with the textbook of choice for trainees and practitioners in haematology.

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Contributor list vii

Preface to the seventh edition x

Preface to the first edition xi

1 Stem cells and haemopoiesis 1Emma de Pater, Elaine Dzierzak

2 Erythropoiesis 11Douglas R Higgs, Noémi Roy, Deborah Hay

3 Iron metabolism iron deficiency and disorders of haem synthesis 21Clara Camaschella, A Victor Hoffbrand, Chaim Hershko

4 Iron overload 40Clara Camaschella, A Victor Hoffbrand, Maria Domenica Cappellini

5 Megaloblastic anaemia 53A Victor Hoffbrand

6 Haemoglobin and the inherited disorders of globin synthesis 72Swee Lay Thein, David Rees

7 Sickle cell disease 98Anne Marsh, Elliott P Vichinsky

8 Hereditary disorders of the red cell membrane and disorders of red cell metabolism 114Paola Bianchi, Narla Mohandas

9 Acquired haemolytic anaemias 138Modupe O Elebute, Rachel Kesse–Adu

10 Inherited aplastic anaemia/bone marrow failure syndromes 156Inderjeet S Dokal

11 Acquired aplastic anaemia and paroxysmal nocturnal haemoglobinuria 174Judith CW Marsh, Austin G Kulasekararaj,, Neal S Young, Peter Hillmen

12 Red cell immunohaematology 195Geoff Daniels, Marcela Contreras, Shubha Allard

13 Clinical blood transfusion 214Shubha Allard, Marcela Contreras

14 Phagocytes 246John Mascarenhas, Marina Kremyanskaya,, Ronald Hoffman

15 Lysosomal storage disorders 270Atul B Mehta, Derralynn A Hughes

16 Normal lymphocytes and non–neoplastic lymphocyte disorders 278Paul Moss, Mark Drayson

17 The spleen 303Paul Moss

18 The molecular basis of haematological malignancies 314Niccolo Bolli, George Vassiliou

19 Laboratory diagnosis of haematological neoplasms 332Torsten Haferlach, Barbara J Bain

20 Acute myeloid leukaemia 352Alan K Burnett, David Grimwade

21 Adult acute lymphoblastic Llukaemia 371Clare J Rowntree, Adele K Fielding

22 Childhood acute lymphoblastic leukaemia 384Ajay Vora

23 Supportive care in the management of leukaemia 399Eliza Gil, Vanya Gant, Panagiotis Kottaridis

24 Chronic myeloid leukaemia 419David TO Yeung, Timothy P Hughes

25 The myelodysplastic syndromes 438Kavita Raj, Ghulam J Mufti

26 Myeloproliferative neoplasms 474Peter J Campbell, Claire Harrison, Anthony R Green

27 Chronic lymphocytic leukaemia and other chronic B–cell disorders 500Emili Montserrat, Peter Hillmen

28 T–cell lymphoproliferative disorders 524Pier Luigi Zinzani, Alessandro Broccoli

29 Multiple myeloma 537Jesús San–Miguel, Joan Bladé

30 Amyloidosis 562Simon DJ Gibbs, Philip N Hawkins

31 The classification of lymphomas: updating the WHO classification 575Elias Campo, Stefano A Pileri

32 Hodgkin lymphoma 601Piers Blombery, David Linch

33 Non–Hodgkin lymphoma: low grade 614William Townsend, Robert Marcus

34 Non–Hodgkin lymphoma: high grade 631Jessica Okosun, Kate Cwynarski

35 Stem cell transplantation 651Charles Craddock, Ronjon Chakraverty

36 Normal haemostasis 676Keith Gomez, John H McVey

37 The vascular function of platelets 699Stephen P Watson, Neil V Morgan, Paul Harrison

38 Haemophilia and VonWillebrand disease 715Michael A Laffan, K John Pasi

39 Rare inherited coagulation disorders 733Flora Peyvandi, Marzia Menegatti

40 Acquired coagulation disorders 743Peter W Collins, Jecko Thachil, Cheng–Hock Toh

41 Congenital platelet disorders 761Maurizio Margaglione, Paul RJ Ames

42 Primary immune thrombocytopenia 773Drew Provan, Adrian C Newland

43 Thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome (congenital and acquired) 783Pier Mannuccio Mannucci, Flora Peyvandi, Roberta Palla

44 Heritable thrombophilia 795Trevor Baglin, David Keeling

45 Acquired venous thrombosis 809Beverley J Hunt, Henry G Watson

46 Antithrombotic agents 820Trevor Baglin, David Keeling

47 Management of venous thromboembolism 830Trevor Baglin, David Keeling

48 Haematological aspects of systemic disease 838A Victor Hoffbrand, Atul B Mehta

49 Haematological aspects of tropical diseases 854Imelda Bates, Ivy Ekem

50 Neonatal haematology 870Irene Roberts, Subarna Chakravorty

51 WHO Classification: Tumours of the Haematopoietic and Lymphoid Tissues (2008) 885

Index 888

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A. Victor Hoffbrand
Douglas R. Higgs
David M. Keeling
Atul B. Mehta
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