Neurology: A Queen Square Textbook has rapidly become established as an essential companion for practising neurologists and those undertaking specialist training in neurology throughout the world.
This second edition has been fully revised and updated to reflect the rapid pace of development in clinical neurology and applied neurosciences. Each chapter incorporates an up–to–date review of recent advances in neurological management and is extensively illustrated with new figures and tables in full colour.
Neurology: A Queen Square Textbook is the only major neurology textbook written entirely from a single institution. It benefits from being edited in a collaborative manner to create consistent and authoritative subspecialty reviews.
Highlights of the new edition include:
- Full–colour illustrations,
- All chapters fully revised and updated to reflect the increasing role of neurologists in acute care,
- Introductory chapters summarising the basic sciences underpinning the practice of clinical neurology, including genetics, channelopathies, immunology, neurophysiology and neuropathology,
- New contributions highlighting major development in the care of stroke, epilepsy, dementia, Parkinson′s disease, multiple sclerosis, neuromuscular disease, headache, infections, spinal disease, cranial nerve disease, neuropsychiatry, neurogenetics, neuro–oncology, uroneurology, neuro–otology, neuro–ophthalmology, pain medicine, sleep medicine, metabolic disease, drugs and toxins, autonomic disease, systemic disease, and neurorehabilitation.
Neurology: A Queen Square Textbook maintains its core goals; to provide a coherent and practical overview of contemporary bedside neurological practice and of the principles which underlie the translation of neurosciences into clinical care.
Editorial Team vii
Principal Editors vii
International Editors vii
Specialist Advisory Editors vii
Foreword to the First Edition xiii
Foreword to the Second Edition xv
1 Neurology Worldwide: The Epidemiology and Burden of Neurological Disease 1Simon Shorvon
2 Nervous System Structure and Function 11Charles Clarke and Roger Lemon
3 Mechanisms of Neurological Disease: Genetics, Autoimmunity and Ion Channels 69Dimitri Kullmann, Henry Houlden and Michael Lunn
4 The Language of Neurology: Symptoms, Signs and Basic Investigations 97Charles Clarke, Matthew Adams, Robin Howard, Martin Rossor, Simon Shorvon and Jason Warren
5 Stroke and Cerebrovascular Diseases 133Nicholas Losseff, Matthew Adams, Martin M. Brown, Joan Grieve and Robert Simister
6 Movement Disorders 187Kailash Bhatia, Carla Cordivari, Mark Edwards, Thomas Foltynie, Marwan Hariz, Prasad Korlipara, Patricia Limousin, Niall Quinn, Sarah Tabrizi and Thomas Warner
7 Epilepsy and Related Disorders 221Simon Shorvon, Beate Diehl, John Duncan, Matthias Koepp, Fergus Rugg ]Gunn, Josemir Sander, Matthew Walker and Tim Wehner
8 Dementia and Cognitive Impairment 289Martin Rossor, John Collinge, Nick Fox, Simon Mead, Catherine Mummery, Jonathan Rohrer, Jonathan Schott and Jason Warren
9 Infection in the Nervous System 337Robin Howard, Carmel Curtis and Hadi Manji
10 Nerve and Muscle Disease 391Michael Lunn, Michael Hanna, Robin Howard, Matthew Parton, Shamima Rahman, Mary Reilly, Katie Sidle and Christopher Turner
11 Multiple Sclerosis and Demyelinating Diseases 475Siobhan Leary, Gavin Giovannoni, Robin Howard, David Miller and Alan Thompson
12 Headache 513Manjit Matharu, Paul Shanahan and Tim Young
13 Cranial Nerve Disorders 531Jeremy Chataway, Charles Clarke, Robin Howard and Paul Jarman
14 Neuro ]Ophthalmology 553James Acheson, Fion Bremner, Elizabeth Graham, Robin Howard, Alexander Leff, Gordon Plant, Simon Shorvon and Ahmed Toosy
15 Neuro ]Otology: Problems of Dizziness, Balance and Hearing 605Rosalyn Davies, Linda M. Luxon, Doris ]Eva Bamiou and Adolfo Bronstein
16 Spinal Column and Spinal Cord Disorders 647Simon Farmer and David Choi
17 Cerebellar Ataxias and Related Conditions 685Nicholas W. Wood
18 Restorative Neurology, Rehabilitation and Brain Injury 699Richard Greenwood, Diana Caine, Ulrike Hammerbeck, Alexander Leff, Diane Playford, Valerie Stevenson andNick Ward
19 Toxic, Metabolic and Physical Insults to the Nervous System and Inherited Disorders of Metabolism 729Robin Howard, Jeremy Chataway, Mark Edwards, Simon Heales, Robin Lachmann, Alexander Leff and Elaine Murphy
20 Disorders of Consciousness, Intensive Care Neurology and Sleep 797Robin Howard, Sofia Eriksson, Nicholas Hirsch, Neil Kitchen, Dimitri Kullmann, Christopher Taylor and Matthew Walker
21 Neuro ]Oncology 849Jeremy Rees, Robert Bradford, Sebastian Brandner, Naomi Fersht, Rolf Jäger and Elena Wilson
22 Neuropsychiatry 905Eileen Joyce
23 Pain 919Paul Nandi
24 Autonomic Aspects of Neurology 945Christopher Mathias, Gordon Ingle and Valeria Iodice
25 Uroneurology 967Jalesh Panicker
26 Systemic Conditions and Neurology 985David Werring, Robin Howard and Simon Shorvon