Neuroimaging, Part One, a text from The Handbook of Clinical Neurology illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging.
This first volume specifically covers a description of imaging techniques used in the adult brain, aiming to bring a comprehensive view of the field of neuroimaging to a varying audience. It brings broad coverage of the topic using many color images to illustrate key points.
Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, and the entire field is moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to this new horizon in the study of neurological disorders.
- Provides a relevant description of the technologies used in neuroimaging, including computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and several others
- Ideal resource for anyone studying the nervous system, from beginners to specialists interested in recent advances in neuroimaging of the adult brain
- Discusses the application of imaging techniques to the study of brain and spinal cord disease and its use in various syndromes
- Contains vibrant, colorful images to illustrate key points
Section I Neuroimaging Methods 1. Computed Tomography Imaging and Angiography: Principles 2. Magnetic Resonance Imaging: Principles 3. Volumetric and Fiber-tracing MRI Methods for Gray and White Matter 4. Functional Magnetic Resonance Imaging 5. Clinical magnetic resonance spectroscopy of the central nervous system 6. Brain perfusion: Computed tomography and magnetic resonance techniques 7. Magnetic resonance angiography: physical principles and applications 8. Diagnostic angiography of the cerebrospinal vasculature 9. Neurosonology and Noninvasive Imaging of the Carotid Arteries 10. Myelography: modern technique and indications 11. Positron Emission Tomography 12. Positron Emission Tomography: Ligand Imaging 13. Single photon emission tomography
Section II Brain Diseases 14. Intra-axial Brain Tumors 15. Extra-axial Brain Tumors 16. Imaging acute ischemic stroke 17. Other Cerebrovascular Occlusive Disease 18. Hemorrhagic Cerebrovascular Disease 19. Infection 20. Multiple Sclerosis 21. Other non-infectious Inflammatory Disorders 22. Imaging neuro-trauma 23. Cerebellar disorders: clinical/radiological findings and modern imaging tools 24. Imaging of genetic and degenerative disorders primarily causing Parkinsonism 25. Genetic and degenerative disorders primarily causing other movement disorders 26. Genetic and Degenerative Disorders Primarily Causing Dementia 27. Neurocutaneous syndromes 28. Cerebrospinal fluid flow in adults 29. Metabolic and endocrine disorders 30. Skull-base Lesions 31. Imaging of orbital disorders
Joseph C. Masdeu, MD, PhD holds the Graham Family Distinguished Endowed Chair in Neurological Sciences at the Houston Methodist Institute of Academic Medicine and leads the Nantz National Alzheimer Center and Neuroimaging at the Houston Methodist Neurological and Research Institutes. He is Professor of Neurology at Weill Cornell Medical College.
Dr. Masdeu is interested in the application of neuroimaging tools, including new molecular neuroimaging markers, to the study of neurodegenerative brain disorders. By clarifying disease mechanisms and providing quantifiable markers of disease progression, this research will lead to the production of new medications and greatly facilitate the testing of new therapies in smaller and better characterized patient samples.
A native of Spain, where he became certified in Psychiatry after his MD degree at the University of Madrid, Dr. Masdeu is a US citizen who completed residency training in Chicago and was certified in Neurology by the American Board of Neurology and Psychiatry in 1976. He was a fellow in Neuropathology at the Brigham and Women's Hospital of Harvard Medical School in 1976-77. In the 1980s, at the Albert Einstein College of Medicine, in New York, he directed the Alzheimer research component of a Program Project on Aging and Dementia. From 1991-2000 he was the Chairman of Neurology at the New York Medical College. He was Professor of Neurology and Director of Neurosciences at the University of Navarra Medical School, in Pamplona, Spain, from 2000-2008 and a Senior Staff Physician and Scientist at the Section of Integrative Neuroimaging of the Clinical Brain Disorders Branch of the Intramural Research Program of the National Institutes of Health (NIMH) from 2008-2014. He is the author of 142 peer-reviewed papers, 61 book chapters, and of seven books, including "Localization in Clinical Neurology,? now in its 6th edition. With a longstanding interest in neuroimaging, he is chairman of the Neuroimaging Research Group of the World Federation of Neurology. He has been a director of the American Academy of Neurology and president of the American Society of Neuroimaging. Since 2007 he is the Editor-in-Chief of the Journal of Neuroimaging.
Gonzalez, R. Gilberto
Dr. R. Gilberto González is Chief of Neuroradiology at the Massachusetts General Hospital and Professor of Radiology at the Harvard Medical School. He received his MD from Harvard Medical School and a PhD in biophysical chemistry from the University of California at Santa Cruz. He did post doctoral work in molecular biophysics at the Francis Bitter National Magnet Lab at MIT. His clinical training included an internship in medicine and a residency in radiology at the Brigham and Women's Hospital in Boston, and a neuroradiology fellowship at the MGH. He has published over 200 original, peer-reviewed scientific papers, over 100 chapters and reviews, and 3 books. He has published in the areas of ischemic stroke, brain tumors, cerebral hemorrhage, AIDS dementia and Alzheimer's disease, and has received research funding from the NIH, foundations and medical enterprises. He has given over 150 invited lectures at universities and at scientific meetings in the US, Europe, Latin America and Asia. He has received several honors including the Outstanding Researcher Award from the American Society of Neuroradiology, and has given the Taveras (Harvard), Newton (UCSF) and Wood (UNC) Lectures. He has reviewed grant applications as a member of NIH study sections and for several scientific organizations. Dr. González has been on the editorial board of the American Journal of Neuroradiology and Neurosurgery and is an ad hoc reviewer for many journals including the New England Journal of Medicine, The Lancet, Radiology and Stroke. He lives in Cambridge with his wife Michele, an atmospheric chemist, and their 2 daughters Susan and Ana.