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Self Administration of High Viscosity Drugs

  • ID: 3498935
  • Report
  • November 2015
  • Region: Global
  • Greystone Associates
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Growth in biological drugs has been driven by advances in biotechnology and host-vector engineering – advances that have led to a steady stream of biologics for a number of ailments and conditions. These powerful drugs come with a high cost-per-dose and the risk of significant side effects – factors that place an elevated emphasis on administration efficiency, safety and reliability. Many drugs in this class are characterized by physical properties and sensitivities that challenge the drug commercialization ecosystem. For example, monoclonal antibodies, perhaps the most significant category in terms of therapeutic and commercial importance, typically possess viscosities that are well above the normal limits of subcutaneous injection techniques. Drug developers and device designers are increasingly working in collaboration to address the goal of patient self-administration for self injecting high viscosity drugs.

What You Will Learn

- Analyzes the market for therapeutic drugs with viscosities that cannot be delivered using standard patient self-injection devices and techniques
- Assesses technologies and devices that are aimed at positioning high viscosity drugs for patient self-administration, including injection devices and viscosity-lowering formulation techniques
- Analyzes design factors, material selection issues, formulation factors, and device capabilities and limitations
- Profiles injectable drug and device participants, their product development activities, business strategies, and corporate alliances and affiliations
- Evaluates key therapeutic sectors for high viscosity injectables
- Provides market data and forecasts to 2020
- Evaluates the impact of economic, technology, and regulatory factors on self-injecting high viscosity drugs
Note: Product cover images may vary from those shown
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1. Executive Summary

2. The Market Opportunity

3. The Economics of Injectable Drugs
- Injectable Drug Trends and Market Drivers
- Prefilled Devices
- Self-Administration
- Shifting Demographics
- Injector Design Innovation
- Therapeutic Demand Drivers
- Competitive Landscape
- Risk Factors

4. High Viscosity Injection Devices – Design Factors

5. Drug Properties (T/C/V)
- Drug Storage Requirements
- Injection Methodology
- Baseline Device Capabilities
- Primary Packaging
- Lyophilized Drugs/Reconstitution
- Human Engineering/Ergonomics
- Formulation Technology

6. High Viscosity Injection – Device Analysis

7. Specialty Autoinjectors
- Plastic Syringes
- Wearable Subcutaneous Infusion Devices
- Patch-like Devices
- Other Device Classes

8. High Viscosity Injectables – the Current Market

9. Combination Products
- Development-stage Products
- Alliances and Collaborations

10. High Viscosity Injectables – Key Therapeutic Sector Analysis

11. Therapy Sectors
- Commercialized Injectables
- Forecasts and Prospects

12. Market Factors

13. Regulatory Initiatives
- Patient Compliance and Ease of Use
- Healthcare Economics
Note: Product cover images may vary from those shown
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