Clostridial Diseases of Animals is the first book to focus on clostridial diseases in domestic and wild animals, offering a comprehensive reference on these common diseases. Emphasizing clinical applications, the book offers a complete, in–depth examination of clostridial disease, from pathogenesis, pathology, and microbiology to diagnostic techniques, clinical management, and treatment. Combining pathology and microbiology, a highlight of the book is the high–quality clinical photographs, which are valuable for recognizing disease patterns.
The book begins with sections on the pathogenic clostridia and the toxins produced, then covers specific diseases produced by the pathogenic clostridia. Clostridial Diseases of Animals summarizes current understanding of clostridial diseases and discusses important areas of diagnostic uncertainty, making it an essential reference for veterinary clinicians, diagnosticians, pathologists, microbiologists, students, and governmental agencies.
- Provides a single resource for all aspects of clostridial diseases
- Presents current, comprehensive information with a focus on clinical relevance
- Covers each disease in depth, including etiology, epidemiology, clinics, gross pathology, histopathology, diagnostics, diagnostic criteria, prophylaxis, control, and treatment
- Written by the world–leading experts in the field of clostridial diseases in animals
- Offers photographs and summary tables to support the concepts discussed in the text and aid in recognition
List of Contributors Xi
Section 1: The pathogenic clostridia
1 Taxonomic Relationships among the Clostridia 3John F. Prescott, Janet I. MacInnes, and Anson K. K. Wu
2 General Physiological and Virulence Properties of the Pathogenic Clostridia 7Julian I. Rood
3 Brief Description of Animal Pathogenic Clostridia 13John F. Prescott
Section 2: Toxins Produced by the Pathogenic Clostridia
4 Toxins of Histotoxic Clostridia: Clostridium chauvoei, Clostridium septicum, Clostridium novyi, and Clostridium sordellii 23Michel R. Popoff
5 Toxins of Clostridium perfringens 45James R. Theoret and Bruce A. McClane
6 Toxins of Clostridium difficile 61J. Glenn Songer, Ashley E. Harmon, and M. Kevin Keel
7 Clostridium botulinum and Clostridium tetani Neurotoxins 71Michel R. Popoff
Section 3: Clostridial Infections of the Gastrointestinal System
8 Diseases Produced by Clostridium perfringens Type A in Mammalian Species 109Francisco A. Uzal
9 NetF Associated Necrotizing Enteritis of Foals and Canine Hemorrhagic Gastroenteritis 117Iman Mehdizadeh Gohari, Valeria R. Parreira, and John F. Prescott
10 Necrotic Enteritis of Poultry 123Kerry K. Cooper and J. Glenn Songer
11 Infections by Clostridium perfringens Type B 139Francisco A. Uzal and J. Glenn Songer
12 Diseases Produced by Clostridium perfringens Type C 143Santiago S. Diab
13 Diseases Produced by Clostridium perfringens Type D 157Francisco A. Uzal, Federico Giannitti, John W. Finnie, and Jorge P. García
14 Infections by Clostridium perfringens Type E, 173J. Glenn Songer
15 Diseases Produced by Clostridium difficile 177Santiago S. Diab, Francisco A. Uzal, and J. Glenn Songer
16 Disease Caused by Clostridium colinum: Ulcerative Enteritis of Poultry and Other Avian Species 197John F. Prescott
17 Clostridial Abomasitis 205John F. Prescott, Paula I. Menzies, and Russell S. Fraser
18 Diseases Produced by Clostridium spiroforme 221J. Glenn Songer and Francisco A. Uzal
Section 4: Clostridial Histotoxic Infections
19 Blackleg 231Camila C. Abreu and Francisco A. Uzal
20 Gas Gangrene (Malignant Edema) 243Rodrigo O. S. Silva, Francisco A. Uzal, Carlos A. Oliveira Jr, and Francisco C. F. Lobato
21 Gangrenous Dermatitis in Poultry 255H. L. Shivaprasad
22 Bacillary Hemoglobinuria 265Mauricio Navarro, Fernando Dutra Quintela, and Francisco A. Uzal
23 Infectious Necrotic Hepatitis 275Mauricio Navarro and Francisco A. Uzal
24 Tyzzer s Disease 281Karina C. Fresneda and Francisco R. Carvallo Chaigneau
Section 5: Clostridial Neurotoxic Infections
25 Tetanus 295Michel R. Popoff
26 Botulism 303Caroline Le Maréchal, Cédric Woudstra, and Patrick Fach
27 Diseases Caused by Other Clostridia Producing Neurotoxins 331John F. Prescott
Francisco A. Uzal, DVM, FRVC, MSc, PhD, Dipl. ACVP, is Professor of Veterinary Diagnostic Pathology at the School of Veterinary Medicine at the University of California at Davis in San Bernardino, California, USA.
J. Glenn Songer, MA, PhD, Fellow AAM, Dipl. ACVM, is Professor (Emeritus) of Veterinary Science and Microbiology, College of Agriculture, The University of Arizona in Tucson, Arizon, USA.
John F. Prescott, MA, Vet MB, PhD, FCAHS, is Professor (Emeritus) of Veterinary Microbiology at Ontario Veterinary College, University of Guelph in Ontario, Canada.
Michel R. Popoff, DVM, PhD, is the head of the Research Unit of Anaerobic Bacteria and Toxins and the National Reference Center for Anaerobic Bacteria and Botulism at Institut Pasteur in Paris, France.