Modern Synthesis Processes and Reactivity of Fluorinated Compounds focuses on the exceptional character of fluorine and fluorinated compounds. This comprehensive work explores examples taken from all classes of fluorine chemistry and illustrates the extreme reactivity of fluorinating media and the peculiar synthesis routes to fluorinated materials.
The book provides advanced and updated information on the latest synthesis routes to fluorocompounds and the involved reaction mechanisms. Special attention is given to the unique reactivity of fluorine and fluorinated media, along with the correlation of those properties to valuable applications of fluorinated compounds.
- Contains quality content edited, and contributed, by leading scholars in the field
- Presents applied guidance on the preparation of original fluorinated compounds, potentially transferable from the lab scale to industrial applications
- Provides practical synthesis information for a wide audience interested in fluorine compounds in many branches of chemistry, materials science, and physics
Chapter One. The Cosmic Origin of Fluorine: An Astronomer's View on Fluorine Synthesis
Chapter Two. The Fluorine Atom in Health Care and Agrochemical Applications: A Contribution to Life Science
3. Industrial Syntheses of Hydrohaloolefins and Related Products
4. Electrochemical Fluorination: A Powerful Tool for the Preparation of Organofluorine Compounds
5. Once Upon a Time Was the Langlois' Reagent: A "Sleeping Beauty
6. Toward CF3S Group: From Trifluoromethylation of Sulfides to Direct Trifluoromethylthiolation
7. Nucleophilic Di- and Trifluoromethylation of CO and CN Bonds
8. Oxidative Trifluoromethylation and Trifluoromethylthiolation
9. Catalytic Enantioselective Fluorination
10. Development of Electrophilic Trifluoromethylating Reagents
11. New Nucleophilic Fluoroalkylations
12. Continuous Flow Selective Direct Fluorination Using Fluorine Gas
13. Synthesis of Fluorinated Nitrogen-Containing Compounds Through Superelectrophilic Activation in Superacid HF/SbF5
14. Visible Light-Induced (Per)fluoroalkylation by Photoredox Catalysis
15. Synthesis of Side Chain Fluorinated Amino Acids and Their Effects on the Properties of Peptides and Proteins
16. Ionic Liquids and Polymers for Battery and Fuel Cells
17. Strategic Incorporation of Fluorine for Drug Discovery and Development
18. Telomerization Reaction of 3,3,3-Trifluoropropene
19. High Oxidation States in Transition Metal Fluorides
20. Photochemical Syntheses of Fluorides in Liquid Anhydrous Hydrogen Fluoride
21. Sol-Gel Synthesis of Metal Fluorides: Reactivity and Mechanisms
22. Solution-Based Synthesis of Nano-Sized TiO2 Anatase in Fluorinating Media
23. Ionic Liquid Materials Based on Fluoroanions
24. Reactivity of Surface Fluorinated TiO2 and TiAl Particles
25. Chemical and Electrochemical Stability of Copper in Molten KF-2HF
Henri Groult is Director of Research of CNRS-UPMC-ESPCI UMR 7612, University of Pierre and Marie Curie (Paris 6) in France. He has devoted his research life to fluorine chemistry, electrochemistry, and molten salt chemistry. His main research subjects are electrolytic production of fluorine gas, fluorine compounds for primary and secondary lithium batteries, and electrochemical properties of molten fluorides and chlorides. He has obtained interesting results on fluorine evolution reaction on carbon electrodes, discharge behavior of carbon-fluorine compounds, charge/discharge characteristics of metal fluorides, and electrochemical properties of molten salts. On these subjects, he published more than 100 papers and 7 books. His activity has played an important role in fluorine chemistry in France. He has served as Director of the French Network of Fluorine, Chairman of the 17th European Symposium on Fluorine Chemistry (Paris, July 2013), and Editorial board of J. Fluorine Chemistry.
Frederic Leroux is CNRS Research Director at the University of Strasbourg. He is Director of the joint CNRS-Bayer laboratory of organofluorine chemistry and director of the molecular chemistry department (UMR CNRS 7042-LIMA) at the European School of Chemistry, Polymers and Material Sciences (ECPM). His research is published in >110 peer-reviewed papers, 18 patents, 8 book chapters and presented by invitation at >100 (inter)national conferences. He is Fellow of the Royal Society of Chemistry (FRSC) and member of the European Academy of Sciences and Arts. He is also a member of the International Scientific Committee of the Moissan Prize (Fluorine Chemistry) and Director of the French Fluorine Network.
His scientific interest covers various fields, based on a fruitful interplay of several objectives (a) the synthesis of biologically relevant molecules, (b) asymmetric methodologies using organic and organometallic chemistry, (c) organofluorine chemistry and (d) application of the objectives to industrial problems, which led to strong industrial collaborations.
Alain Tressaud is Emeritus Research Director at ICMCB-CNRS, Bordeaux University. He is President of the European Academy of Science in Brussels and member of several European academies. He founded and chaired the French Network on Fluorine Chemistry, sponsored by CNRS, until 2008. He has received several awards, including the CEA Award of French Academy of Sciences (2008), the Fluorine Award of the American Chemical Society (2011), and the International Henri Moissan Prize (2013). His scientific interest covers various fields, including synthesis, physical chemical characterizations, applications in fluorine chemistry, solid state chemistry, and materials sciences. His work also deals with surface modification of materials and intercalation chemistry. Professor Tressaud's scientific production includes more than 360 papers in international journals, 20 book chapter contributions, and 12 internationalized patents. He has also edited several books in his role as editor-in-chief of the series "Advances in Fluorine Science (2006) and "Progress in Fluorine Science (2016) with Elsevier.