RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Pipeline Review, H1 2016

  • ID: 3802810
  • Report
  • 58 pages
  • Global Markets Direct
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FEATURED COMPANIES

  • ArQule, Inc.
  • AstraZeneca Plc
  • Merck & Co., Inc.
  • Novartis AG
  • MORE
RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Pipeline Review, H1 2016

Summary

‘RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Pipeline Review, H1 2016’, provides in depth analysis on RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) targeted pipeline therapeutics.

The report provides comprehensive information on the RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) targeted therapeutics development and features dormant and discontinued projects.

The author's report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from their proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data.

Scope

- The report provides a snapshot of the global therapeutic landscape for RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1)
- The report reviews RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) targeted therapeutics and enlists all their major and minor projects
- The report assesses RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) targeted therapeutics

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
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Note: Product cover images may vary from those shown
2 of 5

FEATURED COMPANIES

  • ArQule, Inc.
  • AstraZeneca Plc
  • Merck & Co., Inc.
  • Novartis AG
  • MORE
List of Tables

List of Figures

Introduction

Report Coverage

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) Overview

Therapeutics Development

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Products under Development by Stage of Development

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Products under Development by Therapy Area

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Products under Development by Indication

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Pipeline Products Glance

Late Stage Products

Early Stage Products

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Products under Development by Companies

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Therapeutics Assessment

Assessment by Monotherapy/Combination Products

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Companies Involved in Therapeutics Development

ArQule, Inc.

AstraZeneca Plc

Cipher Pharmaceuticals Inc.

Merck & Co., Inc.

Novartis AG

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Drug Profiles

ARQ-092 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

AZD-5363 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

ISC-4 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

JRP-890 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

MK-2206 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

MK-2206 + selumetinib sulfate - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

trametinib dimethyl sulfoxide + uprosertib - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

uprosertib - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Dormant Projects

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) - Featured News & Press Releases

Jan 28, 2016: ArQule Provides Update on ARQ 092

Nov 17, 2015: ArQule and the National Human Genome Research Institute of the National Institutes of Health Announce Enrollment of First Patient in the Phase 1 Proteus Syndrome Trial With ARQ 092

Nov 08, 2015: BIND Presents Data on MK-2206, at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics

Oct 26, 2015: BIND Therapeutics' Presentation at Upcoming AACR-NCI-EORTC Conference Reinforce Potential of Accurin Platform to Develop Best-in-Class Therapeutics

Oct 15, 2015: ArQule Announces Publication of Manuscript Highlighting Activity of AKT Inhibitor ARQ 092 in Oncology

Sep 28, 2015: ArQule Presents Results From Phase 1b Expansion Study of ARQ 092 at the 2015 European Cancer Conference

Nov 13, 2014: ArQule Announces Data Presentations on ARQ 092 at 26th EORTC-NCI-AACR Symposium

Nov 11, 2014: ArQule Announces Collaboration with NIH for Clinical Development of ARQ 092 in Proteus Syndrome

Oct 21, 2013: New Drug Combinations May Benefit Patients With Pancreatic Cancer

Apr 09, 2013: ArQule’s New AKT Pathway Inhibitor, ARQ 092, Demonstrates Safety, Target Inhibition in Phase I Trial

Apr 07, 2013: AstraZeneca's AKT Inhibitor AZD5363 Well Tolerated, Yieldes Partial Response In Patients With Advanced Solid Tumors, Phase I Study Finds

Nov 10, 2011: Daiichi Sankyo To License ARQ 092 From ArQule, The First New Compound Resulting From The Companies’ Joint AKIP Research Collaboration

Apr 12, 2011: Astex Announces Commencement Of Phase I Study For AZD5363 In Anti-Cancer Collaboration With AstraZeneca

Jun 01, 2009: AstraZeneca and Merck & Co., Inc. Form Pioneering Collaboration to Investigate Novel Combination Anticancer Regimen

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer 58List of Tables

Number of Products under Development for, H1 2016

Number of Products under Development by Therapy Area, H1 2016

Number of Products under Development by Indication, H1 2016

Comparative Analysis by Late Stage Development, H1 2016

Comparative Analysis by Early Stage Products, H1 2016

Number of Products under Development by Companies, H1 2016

Products under Development by Companies, H1 2016

Products under Development by Companies, H1 2016 (Contd..1)

Products under Development by Companies, H1 2016 (Contd..2)

Assessment by Monotherapy/Combination Products, H1 2016

Number of Products by Stage and Mechanism of Action, H1 2016

Number of Products by Stage and Route of Administration, H1 2016

Number of Products by Stage and Molecule Type, H1 2016

Pipeline by ArQule, Inc., H1 2016

Pipeline by AstraZeneca Plc, H1 2016

Pipeline by Cipher Pharmaceuticals Inc., H1 2016

Pipeline by Merck & Co., Inc., H1 2016

Pipeline by Novartis AG, H1 2016

Dormant Projects, H1 2016

Dormant Projects (Contd..1), H1 2016

Dormant Projects (Contd..2), H1 2016 45List of Figures

Number of Products under Development for, H1 2016

Number of Products under Development by Therapy Area, H1 2016

Number of Products under Development by Top 10 Indication, H1 2016

Comparative Analysis by Early Stage Products, H1 2016

Assessment by Monotherapy/Combination Products, H1 2016

Number of Products by Stage and Mechanism of Actions, H1 2016

Number of Products by Routes of Administration, H1 2016

Number of Products by Stage and Routes of Administration, H1 2016

Number of Products by Stage and Molecule Type, H1 2016
Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • ArQule, Inc.
  • AstraZeneca Plc
  • Merck & Co., Inc.
  • Novartis AG
  • MORE
RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) pipeline Target constitutes close to 8 molecules. Out of which approximately 8 molecules are developed by Companies. The author's latest report RAC-Gamma SerineThreonine-Protein Kinase - Pipeline Review, H1 2016, outlays comprehensive information on the RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.

RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) RAC-gamma serine/threonine-protein kinase is an enzyme encoded by the AKT3 gene. AKT3 regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. It plays an important role in brain development and viability of malignant glioma cells. It is required for the coordination of mitochondrial biogenesis with growth factor-induced increases in cellular energy demands. The molecules developed by Companies in Phase II, Phase I and Preclinical stages are 5, 1 and 2 respectively.

Furthermore, this report also reviews key players involved in RAC-Gamma Serine/Threonine-Protein Kinase (Akt-3 or Protein Kinase Akt-3 or Protein Kinase B Gamma or RAC-PK-Gamma or STK-2 or EC 2.7.11.1) targeted therapeutics development, features dormant and discontinued projects and latest news and press releases. Driven by data built using data and information sourced from their proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
Note: Product cover images may vary from those shown
5 of 5
ArQule, Inc.
AstraZeneca Plc
Cipher Pharmaceuticals Inc.
Merck & Co., Inc.
Novartis AG
Note: Product cover images may vary from those shown
6 of 5
Note: Product cover images may vary from those shown
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