Next-Generation Sequencing (NGS) Data Analysis & Interpretation Ecosystem Analysis Report

  • ID: 3829521
  • Report
  • Region: Global
  • 127 Pages
  • EnlightenBio
1 of 5
Detailing an Extensive Ecosystem Analysis of 25 Commercial Companies in the NGS Data Analysis and Interpretation Space, Market Trends, Unmet Needs and Challenges

FEATURED COMPANIES

  • Advaita
  • Bina Technologies
  • CLC Bio (Qiagen)
  • Edico Genome
  • Genospace
  • Partek
  • MORE
The advancements in high-throughput sequencing demand powerful, yet user-friendly bioinformatics solutions to analyze and extract meaningful knowledge from the generated sequence data. In line with this demand, the sequence data analysis and interpretation space is rich with commercial bioinformatics and/or platform solutions that provide different analysis, interpretation, and reporting solutions, and is paralleled by the ever-growing open source tools space. Commercial solutions provide a multitude of bioinformatics offerings as user-friendly stand-alone packages. They each differ in the capabilities offered, the user-friendliness they provide, the product(s) cost, and the target audience. This creates a challenging environment for the end-users faced with selecting the right offering for their specific analysis needs. Accordingly, the commercial entities need to clearly communicate their competitive advantage to customers to be among the winners in this space.

This comparative ecosystem analysis of key commercial tool providers reveals a range of capabilities that uniquely address both secondary and tertiary sequence data analysis needs. At first glance, the value propositions and communication of capabilities seem overlapping or similar. However, a deeper analysis clearly uncovers substantial differences in the product characteristics related to analysis and interpretation, data management, sharing and collaboration, reporting of findings, compliance and security mechanisms, and type of content made available for meaningful knowledge extraction.

A set of 25 commercial companies was analyzed revealing top players who are strong in different areas of data analysis and interpretation: DNAnexus and Seven Bridges Genomics have emerged as open and flexible platforms for data analysis, while Bluebee, Genalice, and Edico Genome, as alternatives, enable fast DNA processing. On the data interpretation side, notable players are Cartagenia (Agilent), Congenica, Ingenuity (Qiagen), Omicia, Station X, Tute Genomics, and WuXi NextCODE (WuXi AppTec). Content is clearly king on the interpretation side, and tertiary companies with rich content are highly valued: it is therefore not surprising to see Ingenuity with its manually curated content receiving high marks, or Omicia with the additional phenotype content being highlighted as value providers. End-user interviewees repeatedly pointed out the challenges associated with the complexity of data analysis which favors complete and integrated solutions that include secondary, tertiary, and reporting capabilities. This is particularly relevant for organizations that have a range of users at different computer sophistication levels. Tute Genomics is a company that was mentioned favorably supporting the entire workflow from data analysis to interpretation, and findings reporting.

While this report does not intend to provide direct recommendations to end-users for specific product selection, the deep-dive analysis is meant to be an insightful review to help researchers and commercial entities choose the best partner for success.

The 127 page Ecosystem Analysis Report consists of 13 Figures, 45 Tables, and 30 comprehensive Company Profiles which includes company metrics, funding details, product details, founder/executive and board information, additional notes, and respective company visions.

Products mentioned:

- BaseSpace Sequence Hub (Illumina)
- HiSeq 2000 (Illumina)
- MiSeq Sequencing System (lllumina)
- Genome Analyzer Sequencing System
- Technology (Illumina)
- Ion Torrent products Ion PGM and Ion Proton (Thermo Fisher Scientific)
- PacBio RS II
- GeneReader system (Qiagen)
- Roche Sequencing (Genia)
- Sequel System (PacBio)
- Oxford Nanopore Sequencing System
- Nanosring's multi-omics platform
- 10xGenomics' Long Read Technology
- Opal Research (Omicia
- Opal Clinical (Omicia)
- Phevor (Omicia)
- Omicia Gene Panels (Omicia)
- GenePool (Station X)
- Ingenuity Variant Analysis IVA (Qiagen)
- Ingenuity Pathways Analysis IPA (Qiagen)
- iReport (Qiagen)
- AWS (Amazon)
- Google Cloud
- China Precision Medicine Cloud (WuXi NextCODE)
- Genalice MAP (Genalice)
- Genalice LINK (Genalice)
- DRAGEN Processor (Edico Genome)
- BaseSpace Clarity LIMS (GenoLogic platform
- Illumina)
- BaseSpace Variant Interpreter (Illumina)
- BaseSpace Cohort Analyzer (Illumina)
- BaseSpace Correlation Engine (Illumina)
- Bina RAVE (Bina Technologies
- Roche)
- Bina AAiM (Bina Technologies
- Roche)
- Bluebee
- CLC desktop products (Qiagen)
- CLC enterprse solutions (Qiagen)
- Sapientia technology platform (Congenica)
- DNAnexus
- Seven Bridges Genomics
- Clinical Sequence Analyzer CSA (WuXi NextCODE)
READ MORE
Note: Product cover images may vary from those shown
2 of 5

FEATURED COMPANIES

  • Advaita
  • Bina Technologies
  • CLC Bio (Qiagen)
  • Edico Genome
  • Genospace
  • Partek
  • MORE
Objectives
Learnings
Table of Figures
Table of Tables

1. The NGS Process
- User Type
 - - The non-computational researcher
 - - The computational researcher
- User Requirements
 - - Non-computational user requirements
 - - Computational user requirements
 - - Mixed user, large project team requirements
- NGS Target Users - Unmet Needs and Challenges
 - - End-user sequencing instrument preferences
 - - End-user wet-lab challenges
 - - The end-users unmet needs and challenges

2. The NGS Analysis and Interpretation Ecosystem
- End-User Feedback on Secondary analysis
- End-User Feedback on Tertiary Analysis
- NGS Utilization and Analysis Challenges
 - - Secondary analysis companies addressing NGS utilization and analysis challenges
 - - Tertiary interpretation companies addressing NGS utilization and analysis challenges
- Secondary Data Analysis and Tertiary Interpretational Tool Companies Side-by-Side
- Analysis and Interpretation Tool Companies - A Comparative Functionality Assessment
 - - Data analysis speed, scalability, and flexibility
 - - Infrastructure requirements
 - - Data security and compliance features
 - - Sequencing machine integration
- Tertiary Data Interpretation Companies
 - - Tertiary interpretation content
- Partnerships
 - - Overview of partnerships in the analysis and interpretation space
- Company Momentum
 - - The funding situation

3. Extracted Findings

4. Concluding Notes
- Data Explosion
- Training Non-Computational Scientists
- Information Management
- Knowledge Extraction and Actionable Reporting
- End-to-End-Solutions
- Reporting of Clinical Findings

5. Company/Product Profiles
- Advaita
- Agilent Technologies
- Appistry
- BaseSpace (Illumina)
- Bina Technologies
- Biomatters
- Bluebee
- Cartagenia (Agilent)
- CLC Bio (Qiagen)
- Congenica
- DNAnexus
- DNASTAR
- Edico Genome
- Genalice
- Genestack
- Genomatix Software GmbH
- Genospace
- Golden Helix
- Ingenuity with IPA and IVA (Qiagen)
- Omicia
- Pacific Biosciences
- Partek
- Qiagen
- Seven Bridges Genomics
- SoftGenetics
- SolveBio
- Station X
- Thermo Fisher Scientific
- Tute Genomics
- Wuxi NextCODE Genomics

6. Appendix
- Companies in the data analysis and interpretation space
- Abbreviations

About the publisher
Note: Product cover images may vary from those shown
3 of 5

Loading
LOADING...

4 of 5
- Advaita
- Agilent Technologies
- Appistry
- BaseSpace (Illumina)
- Bina Technologies
- Biomatters
- Bluebee
- Cartagenia (Agilent)
- CLC Bio (Qiagen)
- Congenica
- DNAnexus
- DNASTAR
- Edico Genome
- Genalice
- Genestack
- Genomatix Software GmbH
- Genospace
- Golden Helix
- Ingenuity with IPA and IVA (Qiagen)
- Omicia
- Pacific Biosciences
- Partek
- Qiagen
- Seven Bridges Genomics
- SoftGenetics
- SolveBio
- Station X
- Thermo Fisher Scientific
- Tute Genomics
- Wuxi NextCODE Genomics
Note: Product cover images may vary from those shown
5 of 5
Note: Product cover images may vary from those shown
Adroll
adroll