Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Pipeline Review, H2 2016

  • ID: 3832301
  • Report
  • 28 pages
  • Global Markets Direct
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Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Pipeline Review, H2 2016

Summary

‘Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Pipeline Review, H2 2016’, provides in depth analysis on Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) targeted pipeline therapeutics.

The report provides comprehensive information on the Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) , targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) targeted therapeutics development and features dormant and discontinued projects.

The report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data.

Scope

- The report provides a snapshot of the global therapeutic landscape for Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18)
- The report reviews Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) targeted therapeutics and enlists all their major and minor projects
- The report assesses Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) targeted therapeutics

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
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List of Tables

List of Figures

Introduction

Report Coverage

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) Overview

Therapeutics Development

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Products under Development by Stage of Development

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Products under Development by Therapy Area

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Products under Development by Indication

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Pipeline Products Glance

Early Stage Products

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Products under Development by Companies

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Products under Development by Universities/Institutes

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Therapeutics Assessment

Assessment by Monotherapy/Combination Products

Assessment by Mechanism of Action

Assessment by Molecule Type

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Companies Involved in Therapeutics Development

Selvita S.A.

Takeda Pharmaceutical Company Limited

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Drug Profiles

BTZO-2 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

HYCO-1 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

SEL-303 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecule to Activate HO-1 for Endothelial Dysfunction, Asthma and Osteoarthritis - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecules to Activate HO-1 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) - Dormant Projects

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer 28List of Tables

Number of Products under Development for, H2 2016

Number of Products under Development by Therapy Area, H2 2016

Number of Products under Development by Indication, H2 2016

Comparative Analysis by Early Stage Products, H2 2016

Number of Products under Development by Companies, H2 2016

Products under Development by Companies, H2 2016

Number of Products under Investigation by Universities/Institutes, H2 2016

Products under Investigation by Universities/Institutes, H2 2016

Assessment by Monotherapy/Combination Products, H2 2016

Number of Products by Stage and Mechanism of Action, H2 2016

Number of Products by Stage and Molecule Type, H2 2016

Pipeline by Selvita S.A., H2 2016

Pipeline by Takeda Pharmaceutical Company Limited, H2 2016

Dormant Projects, H2 2016

Dormant Projects (Contd..1), H2 2016 26List of Figures

Number of Products under Development for, H2 2016

Number of Products under Development by Therapy Area, H2 2016

Number of Products under Development by Indication, H2 2016

Comparative Analysis by Early Stage Products, H2 2016

Assessment by Monotherapy/Combination Products, H2 2016

Number of Products by Mechanism of Actions, H2 2016

Number of Products by Stage and Mechanism of Actions, H2 2016

Number of Products by Stage and Molecule Type, H2 2016
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Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) pipeline Target constitutes close to 5 molecules. Out of which approximately 2 molecules are developed by Companies and remaining by the Universities/Institutes. Our latest report Heme Oxygenase 1 – Pipeline Review, H2 2016, outlays comprehensive information on the Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.

Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) Heme oxygenase 1 is an enzyme encoded by HMOX1 gene. Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. It exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. The molecules developed by Companies in Preclinical and Discovery stages are 1 and 1 respectively. Similarly, the Universities portfolio in Preclinical and Discovery stages comprises 1 and 2 molecules, respectively.

Furthermore, this report also reviews key players involved in Heme Oxygenase 1 (HO1 or HMOX1 or EC 1.14.14.18) targeted therapeutics development, features dormant and discontinued projects and latest news and press releases. Driven by data built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
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Selvita S.A.
Takeda Pharmaceutical Company Limited
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