Handbook of Cannabis and Related Pathologies

  • ID: 3833354
  • Book
  • 1170 Pages
  • Elsevier Science and Technology
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Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs.

Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug's effects from across scientific disciplines.

This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders.

Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects.

  • Comprehensive chapters include an abstract, key facts, mini dictionary of terms, and summary points
  • Presents illustrations with at least six figures, tables, and diagrams per chapter
  • Provides a one-stop-shopping synopsis of everything to do with cannabis and its related pathology, from chemicals and cells, individuals and communities, and diagnosis and treatment
  • Offers an integrated and informed synopsis of the complex issues surrounding cannabis as a substance, its use, and its misuse
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  1. The Cannabis Plant: Botanical Aspects
  2. The biosynthesis of cannabinoids
  3. Increasing plant concentrations of THC and implications on health related disorders
  4. Age as a Predictor of Cannabis Use
  5. Lifetime cannabis use and cognition in psychosis spectrum disorders
  6. A Profile of Synthetic Cannabinoid Users
  7. Dual disorders in cannabis misuse
  8. Cannabis use and cognitive function
  9. Cannabis, migration and psychosis onset
  10. The global epidemiology and disease burden of cannabis use and dependence
  11. International aspects of cannabis use and misuse
    the Australian perspective
  12. International aspects of cannabis use and misuse: Egypt
  13. Cannabis Body Packing
    A Caribbean Perspective
  14. Gender differences in cannabis use disorders
  15. The role of age in the onset and further development of cannabis use disorders
  16. Effects of Cannabis Use on Neurocognition in Adolescents and Emerging Adults with Psychiatric Comorbidities
  17. Correlates and consequences of prenatal cannabis exposure (PCE): identifying and characterizing vulnerable maternal populations and determining outcomes for exposed offspring
  18. Cannabis and clubbing: Relevance of cannabis and polydrug use in the clubbing culture today
  19. Cannabis and Sexual Behavior
  20. Friendships and Cannabis Use
  21. Students' knowledge of cannabis
  22. Childhood trauma and cannabis
    risk factors in severe mental disorders
  23. Parent's Influence on Their Children's Cannabis Use
  24. Cannabis Users and Premorbid Intellectual Quotient (IQ)
  25. Cannabis and traffic accidents
  26. Drug-related pictures, attentional bias, and cannabis use
  27. Cannabis use and first-episode psychosis patients (FEP)
  28. Cannabis, associative memory, fMRI, and the Implicit Association Test
  29. Stress Response in Cannabis Users and Psychosis
  30. Motivation in Chronic Cannabis Use
  31. Cannabis use and its association to mental illness: a focus on mood and anxiety disorders
  32. Cannabis Use and Well-being
  33. Craving and cannabis: A potential paradox
  34. Delta 9-tetrahydrocannabinol and catalepsy-like immobilization
  35. The interactive nature of cannabis and schizophrenia risk genes
  36. Neuroimaging findings in Adolescent Cannabis use and Early Phase Psychosis
  37. Cannabis smoking in adult schizophrenia: A cognitive and functional magnetic resonance imaging perspective
  38. The long-lasting effects of cannabis use on movement and brain regions that control movement
  39. Assessment of cannabis acute effects on driving skills: laboratory, simulator and on road studies
  40. Chronic cannabis use and axonal fibre connectivity
  41. Microglial activation and cannabis exposure
  42. Cannabis and psychosis: correlation, causality and consequences
  43. Cannabis use and cannabis use disorders in bipolar disorder
    causes and consequences
  44. Cannabis use in epilepsy
    risks and benefits
  45. Cannabis, cannabinoids and visceral pain.
  46. Cannabis and Post-Operative Analgesia
  47. Chronic cannabis abuse and thyroid function
  48. Cannabis Hyperemesis Syndrome
  49. Cannabis and Cannabinoids and the effects on gastrointestinal function: an overview
  50. Cardiovascular Effects of Cannabis Usage
  51. Cannabis and Stroke
  52. Cannabis Smoking and the Lung
  53. Cannabis and hepatic injury
  54. Cannabis allergy: more than a bad trip
  55. Marijuana and Breastfeeding
  56. Hypocretins/orexins and addiction: role in cannabinoid dependence
  57. Regulatory role of cannabinoids for skin barrier functions and cutaneous inflammation
  58. Cannabinoids and the Cannabinoid Receptors: An Overview
  59. Signalling and Regulation of the Cannabinoid CB1 Receptor
  60. Allosteric modulation of the Cannabinoid CB1 Receptor
  61. The polymorphisms of the CB2 cannabinoid receptor
  62. Chemistry of Cannabinoid Receptor Agonists
  63. The endocannabinoid system as a target for new antiseizure drugs
  64. Pharmacological aspects of anandamide and 2-arachidonoyglycerol as bioactive lipids
  65. Pharmacological aspects of NMDA receptors, mGluR5, and endocannabinoids
  66. Peripheral CB1 receptors and ghrelin in feeding regulation. Pharmacological implications.
  67. Pharmacological aspects of novel antiobesity agents related to cannabinoids
  68. Cannabinoid reward and dependence: Focus on the main psychoactive ingredients of marijuana in preclinical studies
  69. Peroxisome proliferator activated receptors and cannabinoids VRP suggested Peroxisome proliferator activated receptors (PPARs) and cannabinoids
  70. The Protein-Protein interactions of CRIP1a and cannabinoid 1 receptor: the molecular mechanism study through an integrated molecular modeling approach
  71. Synthetic cannabinoids: A summary of selected phenomena with respect to behavioral pharmacology and abuse liability
  72. The role of 5-HT1A receptor and nausea and vomiting relief by cannabidiol (CBD), cannabidiolic acid (CBDA) and cannabigerol (CBG)
  73. Genetic and molecular aspects of addiction with tetrahydrocannabinol
  74. Effects of dlta ?9-Tetrahydrocannabinol in human breast cancer
  75. ?9-THC and COX-2 Signaling
  76. Cannabinoids and the addictive effects of nicotine
  77. Cannabinoid Regulation of Intraocular Pressure: Human and Animal Studies, Cellular and Molecular Targets
  78. Ocular Delivery of Tetrahydrocannabinol
  79. The role of g-aminobutyric acid in the interoceptive effects of oral D9-tetrahydrocannabinol in humans
  80. The role of the delta-9-tetrahydrocannabinol in diabetes mellitus
  81. Cannabidiol: An Overview of its Antipsychotic Properties
  82. Cannabidiol for the treatment of epilepsy: an overview of possible mechanisms of action and preclinical and human studies
  83. Cannabidiol and neuroprotection: evidence from preclinical studies
  84. Cannabinoids as Potent Inhibitors of Human CYP1 Enzymes
  85. Nabilone: Pharmacology and Clinical Applications (Suggest: The Synthetic Analogue of delta 9-tetrahydrocannabinol (THC): Nabilone. Pharmacology and Clinical Application)
  86. Synthetic cannabinoids in dementia
  87. Synthetic cannabinoid receptor agonists ("Spice") as new recreational psychoactive substances
  88. Accidents and synthetic cannabinoids in blood of drivers
  89. Cannabis and synthetic cannabinoids for cancer patients: Multiple palliative indications together with promising laboratory anti-neoplastic effects
  90. The Use of Medical Marijuana in the Treatment of Psychiatric Disorders
  91. Beneficial effects of cannabis and related compounds on sleep
  92. Cannabinoids for the treatment of Gilles de la Tourette syndrome
  93. Cannabidiol and multiple sclerosis
  94. Cannabinoids and Effects on Painful Neuropathy
  95. Cannabis for basal ganglia disorders (Parkinson's disease and Huntington's disease)
  96. Medical cannabis for the treatment of Inflammatory Bowel Disease
  97. Cannabidiol for the treatment of drug use disorders
  98. Cannabinoids and the effects on gastrointestinal tract: a focus on motility
  99. Potential medical uses of cannabigerol: a brief overview
  100. The Cannabis Abuse Screening Test (CAST) and applications
  101. Screening of synthetic cannabinoids
  102. On-site Drug testing for Cannabis
  103. Cannabinoids in Oral Fluid: Identification and Interpretation of Analytical Results
  104. Cannabinoids in exhaled breath
  105. Barriers to treatment seeking for cannabis dependence
  106. Pharmacotherapies for cannabis use disorders
  107. Self-Initiated Cannabis Use Cessation in Adolescents and Emerging Adults
  108. Treating cannabis dependent adolescents with family therapy
  109. Cognitive Behavioral Therapy in Cannabis Use Disorder
  110. Cannabis withdrawal symptoms in cannabis and poly drug users
  111. School-based cannabis prevention programs
  112. The CapOpus trial for cannabis use disorders
  113. Treating cannabis use disorders through technology assisted interventions: the telephone and internet
  114. Reducing cannabis use with a real-time intervention using mobile technology
  115. Further information: Cannabis Neuropathology Resources and Recommended Reading

Online Only Chapters:

  1. Tetrahydrocannabinol concentration and genetic characterization of cannabis.
  2. Cannabis Use in Youth Subcultures
  3. Aggressive Behavior and Cannabis Use
  4. COMT genotypes, cannabis use and psychosis: gene-environment interaction evidence from human populations and its methodological concerns
  5. Neuroimaging and genetics of acute and chronic cannabis effects
  6. Grey matter, lateral ventricle volumes and executive functioning in cannabis users with first-episode psychosis
  7. Comorbidity Between Cannabis Use and Attention-Deficit/Hyperactivity Disorder: Potential Moderators
  8. Cannabis and Oral Bones: Deleterious Effects on Periodontitis and Dental Implants
  9. Does cannabis use increase the risk of developing cancer in humans?
  10. Cannabis and the use of amphetamine-like substances
  11. Cannabinoid signaling in glioma cells and therapeutic implications
  12. Cannabidiol as antioxidants
  13. The anxiolytic effects of cannabidiol (CBD).
  14. New Ethological and Morphological Perspectives for the Investigation of Panicolytic-Like Effects of Cannabidiol
  15. Spice Use amongst United States Military Personnel
  16. Cannabis use in fibromyalgia
  17. Short instruments to screen for "problematic" cannabis use in general population surveys: a systematic review
  18. Self-report of cannabis use
  19. CANDIS Program: Modular Treatment of Cannabis Use Disorders
  20. Engaging Cannabis Users in Treatment
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Preedy, Victor R.
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a senior member of King's College London. He is also Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine.

Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well being. He is a member of the Editorial Board of Drug and Alcohol Dependence and a founding member of the Editorial Board of Addiction Biology. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is Editor of the influential works The Handbook Of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse and The Handbook of Cannabis and Related Pathologies (all published by Academic Press-Elsevier).

Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctoral degree (DSc). Professor Preedy was elected as a Fellow of the Institute of Biology in 1995 and also as a Fellow to the Royal College of Pathologists in 2000. He was then elected as a Fellow of the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health and Hygiene (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry.

To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

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