Epicast Report: Acute Coronary Syndrome - Epidemiology Forecast to 2025

  • ID: 3845264
  • Drug Pipelines
  • 79 pages
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Acute coronary syndrome (ACS) is a serious cardiovascular disease associated with high healthcare costs, frequent recurrences and hospitalizations, and high risks of sudden death and short-term mortality. The ACS incidence increases with age and will be a significant public health problem as the elderly population increases around the world.

ACS is an umbrella term that describes conditions in which blood flow to the heart is blocked or reduced due to atherosclerotic plaques composed of white blood cells, cholesterol, and fat. ACS is classified into three disease entities based on evidence of heart muscle damage inferred from a person’s symptoms, changes in the ST tracing of the electrocardiogram (ECG), and levels of cardiac biomarkers that signify heart muscle death.

Epidemiologists forecast that in the 7MM, the diagnosed prevalent cases of ACS will grow from 25.45 Million cases in 2015 to 30.62 Million cases in 2025, at an Annual Growth Rate (AGR) of 2.03%. Throughout the forecast period, the diagnosed prevalent cases of ACS in the US will constitute the highest proportion in the 7MM at approximately 54%.

In the 7MM, the diagnosed prevalent cases of ACS will be higher in men (61.81%) and in the age group older than 65 years (62.84%). STEMI, NSTEMI, and UA will constitute approximately 25%, 40%, and 35% of the diagnosed prevalent cases of ACS in the 7MM.

In the 7MM, epidemiologists project ACS hospitalizations to increase from 1.63 Million cases in 2015 to 1.71 Million cases in 2025 at an AGR of 0.51%. The US constitutes around 40% of the total hospitalized ACS cases in the 7MM for the year 2015 and will be the market with the highest number of cases during the forecast period. In 2015, the majority of the ACS hospitalizations occurred in men (62.85%) and in the age group older than 65 years (69.34%).

The report “EpiCast Report: Acute Coronary Syndrome - Epidemiology Forecast to 2025” provides an overview of the risk factors, comorbidities, and the global and historical trends for ACS in the seven major markets (7MM) (US, France, Germany, Italy, Spain, UK, and Japan). It includes a 10-year epidemiological forecast from 2015-2025 for the diagnosed prevalent cases of ACS, segmented by sex, age (in 10 year age groups from ages =25 years), and ACS type (STEMI, NSTEMI, and UA), and a 10-year epidemiological forecast for ACS hospitalizations, segmented by sex and ACS type (STEMI, NSTEMI, and UA).
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1.1 List of Tables

1.2 List of Figures

2 Epidemiology

2.1 Disease Background

2.2 Risk Factors and Comorbidities

2.3 Global Trends

2.3.1 ACS Diagnosed Prevalence

2.3.2 STEMI and NSTEMI Trends

2.3.3 ACS Hospitalizations

2.4 Forecast Methodology

2.4.1 Sources Used

2.4.2 Forecast Assumptions and Methods

2.4.3 Sources Not Used

2.5 Epidemiological Forecast for ACS (2015-2025)

2.5.1 Diagnosed Prevalent Cases of ACS

2.5.2 Age-Specific Diagnosed Prevalent Cases of ACS

2.5.3 Sex-Specific Diagnosed Prevalent Cases of ACS

2.5.4 Diagnosed Prevalent Cases of ACS Segmented by STEMI, NSTEMI, and UA

2.5.5 Age-Standardized Diagnosed Prevalence of ACS

2.5.6 ACS Hospitalizations

2.5.7 Sex-Specific ACS Hospitalizations

2.5.8 ACS Hospitalizations Segmented by STEMI, NSTEMI, and UA

2.6 Discussion

2.6.1 Epidemiological Forecast Insight

2.6.2 Limitations of the Analysis

2.6.3 Strengths of the Analysis

3 Appendix

3.1 Bibliography

3.2 About the Authors

3.2.1 Epidemiologists

3.2.2 Reviewers

3.2.3 Global Director of Therapy Analysis and Epidemiology

3.2.4 Global Head of Healthcare

3.3 About us

3.4 About EpiCast

3.5 Disclaimer

1.1 List of Tables

Table 1: Risk Factors and Comorbidities for ACS

Table 2: Global, Crude Total Population Prevalence Percentages of Angina Pectoris and Mean Age of Study Participants

Table 3: 7MM, Sources of Diagnosed Prevalence Data for MI

Table 4: 7MM, Data Sources of STEMI and NSTEMI Proportions Among Diagnosed Prevalent Cases of MI

Table 5: 7MM, Data Sources of ACS Hospitalizations

Table 6: 7MM, Data Sources of STEMI and NSTEMI Proportions Among MI Hospitalizations

Table 7: 7MM, Diagnosed Prevalent Cases of ACS, Ages =25 Years, Both Sexes, N, Select Years, 2015-2025

Table 8: 7MM, Age-Specific Diagnosed Prevalent Cases of ACS, Men and Women, N (Row %), 2015

Table 9: 7MM, Sex-Specific Diagnosed Prevalent Cases of ACS, Ages =25 Years, N (Row %), 2015

Table 10: 7MM, Diagnosed Prevalent Cases of STEMI, NSTEMI, and UA, Ages =25 Years, N (Row %), 2015

Table 11: 7MM ACS Hospitalizations, Ages =25 Years, Both Sexes, N, Select Years, 2015-2025

Table 12: 7MM, Sex-Specific ACS Hospitalizations, Ages =25 Years, N (Row %), 2015

Table 13: 7MM, Diagnosed ACS Hospitalizations Segmented by STEMI, NSTEMI and UA, Ages =25 Years, Both Sexes, N, 2015

1.2 List of Figures

Figure 1: US, Germany, and UK, Crude Diagnosed MI Prevalence in Men and Women, 1990-2008

Figure 2: Global, Crude Total Population Prevalence Percentages of Angina Pectoris (%)

Figure 3: Case Segmentation Map

Figure 4: 7MM, Diagnosed Prevalent Cases of ACS, Ages =25 Years, Both Sexes, N, Select Years, 2015-2025

Figure 5; 7MM, Age-Specific Diagnosed Prevalent Cases of ACS, Men and Women, N, 2015

Figure 6: 7MM, Sex-Specific Diagnosed Prevalent Cases of ACS, Ages =25 Years, N, 2015

Figure 7: 7MM, Diagnosed Prevalent Cases of STEMI and NSTEMI, Ages =25 Years, N, 2015

Figure 8: 7MM, Age-Standardized Diagnosed Prevalence of ACS, Ages =25 Years, 2015

Figure 9: 7MM ACS Hospitalizations, Ages =25 Years, Both Sexes, N, Select Years, 2015-2025

Figure 10: 7MM, Sex-Specific ACS, Ages =25 Years, N, 2015

Figure 11: 7MM, Diagnosed ACS Hospitalizations Segmented by NSTEMI and STEMI, Ages =25 Years, Both Sexes, N, 2015
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