The Digestive System in Systemic Autoimmune Diseases, Second Edition, represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases. This volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations. International in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico, and South Africa share their knowledge in this detailed volume. The book provides an overview of our current understanding of digestive disorders in the most common systemic autoimmune diseases.
- Completely updated, including five new chapters
- Presents up-to-date information, giving the reader easy access to individual topics in one place
- Written by leading international clinical and scientific experts on autoimmune and digestive diseases
- Provides a practical guide to the identification, diagnosis, and treatment of digestive involvement in patients with autoimmune diseases that will be useful for all medical specialties
- Includes several diseases and conditions not included in other texts, some of which have only recently emerged
- Designed to serve as a guide to clinical practice
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Section I Introduction 1. Digestive System and Autoimmunity 2. Immunopathogenesis of Autoimmune Liver Damage 3. Autoantibodies in Gastrointestinal Autoimmune Diseases 4. Imaging Techniques in Digestive Diseases
Section II Autoimmune Liver Diseases 5. Primary Biliary Cholangitis 6. Autoimmune Hepatitis 7. Primary Sclerosing Cholangitis
Section III Autoimmune Manifestations of Viral Hepatitis 8. Systemic and Autoimmune Manifestations of Hepatitis B Virus Infection 9. Extrahepatic Manifestations in Patients With Chronic Hepatitis C Virus Infection 10. New Antivirals for Extrahepatic Manifestations of Hepatitis C Virus: The Model of Mixed Cryoglobulinemia Vasculitis
Section IV Gastrointestinal Involvement of Systemic Diseases 11. Systemic Lupus Erythematosus 12. Digestive Involvement in the Antiphospholipid Syndrome 13. Gastrointestinal Involvement in Systemic Sclerosis 14. Gastrointestinal Involvement in Inflammatory Myositis 15. Digestive Involvement in Primary Sjögren's Syndrome 16. Gastrointestinal Involvement in Systemic Vasculitis 17. Mixed Connective Tissue Disease 18. Gastrointestinal Manifestations of Rheumatoid Arthritis 19. Spondyloarthritis and Gastrointestinal Involvement 20. Intestinal Behçet's Disease 21. Gastrointestinal Involvement of Sarcoidosis 22. IgG4-Related Disease: Gastrointestinal Involvement 23. Gastrointestinal Complications of Antirheumatic Drugs
Dr. Manuel Ramos-Casals (MD, PhD) is Specialist Physician in the Systemic Autoimmune Diseases Unit (Hospital Clinic, Barcelona, Spain). Dr Ramos-Casals is a clinically trained internist and researcher, with a special interest in Sjögren's syndrome, cryoglobulinemia and HCV-related autoimmunity. He has developed several clinical and basic research projects on primary SS and is trained in research methodology and experimental models of autoimmunity. He has published in the last 3 years various publications in the best journals in Rheumatology and Internal Medicine (see above). Dr. Ramos-Casals is Assistant Professor in Immunology Diseases, in the Department of Medicine of the University of Barcelona.
Munther Khamashta is Professor/Consultant Physician and Director of The Graham Hughes Lupus Research Laboratory at St Thomas' Hospital, London, and runs a large lupus pregnancy clinic. He studied medicine in Barcelona and internal medicine in Madrid, Spain, where he developed an interest in connective tissue diseases and received his PhD. He was awarded the MRCP in 1999 and FRCP in 2002. He joined the Lupus Unit in London 25 years ago and has been instrumental in developing it into an internationally recognised tertiary centre receiving referrals from all over the UK, see https://kclpure.kcl.ac.uk/portal/en/persons/munther-khamashta(e30b3284-8df1-4cc2-9856-9bca61db843e)/biography.html
Fabiola Atzeni received her degree in Medicine in 1995 from University of Cagliari and accreditation in Rheumatology in 2000. She received her Philosophy Doctorate in Experimental Immunology from University of Barcelona (2005). She is currently an Associate Professor and Senior Consultant at University of Messina. Before her current role, she was a Physician and Clinical Researcher at the Department of Rheumatology, Hospital L. Sacco, Milan.
Her clinical and research interest lies in immunotherapies in autoimmune diseases with particular focus on the investigation and management of differential response to biological therapies in rheumatoid arthritis (RA) and Spondyloarthritis (SpA), cardiovascular aspects of the different rheumatic diseases with particular emphasis on arteriosclerosis and infectious aspects