Organo Catalysis Using Bronsted Acids covers the recent development in asymmetric catalysis involving chiral Bronsted acids that generally prevent the use of toxic or expensive transition metals. The authors draw upon their synthesis, the availability of the catalyst, and the acidity scale. The synthetic scope of each catalyst is evaluated with recent examples of original chemical reactions.
As the field of asymmetric catalysis is evolving dramatically, and with the recent discovery of new and efficient chiral Bronsted acids, there has been rejuvenation in new asymmetric transformations in very mild conditions that are in agreement with the concept of green chemistry. This book is an essential reference with extensive coverage of this growing research area.
- Explores recent developments in asymmetric catalysis for more selective, milder, and environmentally-friendly processes based on the use of original chiral Bronsted acids
- Provides important updates from recent research in the field
- Focuses on using chiral Bronsted acids to eliminate need for toxic or expensive transition metals
2. Childhood: seminal contributions, activation of imines
3. Maturity: toward more general catalysts, stronger acids
4. Seniority: Recent developments
Cooperative catalysis (2014-2016)
5. Synthesis of the catalysts
Jerome Blanchet graduated from the Rouen University Institute of Technology in 1994 and Ecole Nationale Supérieure de Chimie de Clermont-Ferrand in 1997 resepctively. He received his PhD in organic chemistry in 2001. In 2014, he received the accreditation to supervise research at the University of Caen Basse-Normandie. Since 2004 he has worked as a Researcher at CNRS' Molecular Chemistry Laboratory Thioorganic. After being a lecturer at the University of Caen Basse-Normandie for eight years, Jacques Rouden is, since February 2005, organic chemistry professor at the École nationale supérieure d'ingénieurs de Caen (ENSICAEN). Within this school, he performed his research in molecular chemistry laboratory and Thio-organic (UMR CNRS 6507).
After being a lecturer at the University of Caen Basse-Normandie for eight years, Jacques Rouden is, since February 2005, organic chemistry professor at the École nationale supérieure d'ingénieurs de Caen (ENSICAEN). Within this school, he performed his research in molecular chemistry laboratory and Thio-organic (UMR CNRS 6507). His research focuses on the development of eco-compatible asymmetrical methods catalyzed by chiral organic molecules - or organocatalysis - for the production of molecular bricks used in synthesis of biologically active molecules or for medical imaging.