To fill the need pharmaceutical scientists have when developing these drugs,Fixed Dose Combinations for Solid Oral Drug Delivery presents a systematic guide to this class of therapeutics. Chapters address various topics related to the clinical considerations, suitability of drug types and therapeutic categories, as well as successful formulation development and manufacturing of FDC products. The contributing authors who work on the frontlines of the global drug and regulatory industries include case studies to illustrate the best practices as well as challenges involved during development, manufacturing, and quality management.
Outlining the steps for developing FDC drugs, this book:
Deals with a growing part of the pharmaceutical industry, as FDCs are ideal for targeting many chronic illnesses and for reducing the number of medications an increasingly–aging population needs to take
Ensures consistency in the delivery of FDC medication, which can be pivotal in increasing patient compliance and quality of life
Collects dispersed knowledge from patents in addition to scientific and clinical literature so researchers can access a single source reference
Covers regulatory guidelines from around the world and looks ahead at developing areas of personalized medicine for FDCs
Amitava Mitra, PhD, works in the Biopharmaceutics group at Merck Research Labs. His main research interests include pharmacokinetics, biopharmaceutics, and modeling and simulation of oral and alternate drug delivery systems. He has published more than 20 research and review articles in peer–reviewed journals and book chapters.