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Drug Overdose - Pipeline Review, H2 2020

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    Drug Pipelines

  • 79 Pages
  • September 2020
  • Region: Global
  • Global Markets Direct
  • ID: 5174810
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Summary

The publisher's latest Pharmaceutical and Healthcare disease pipeline guide Drug Overdose - Pipeline Review, H2 2020, provides an overview of the Drug Overdose (Toxicology) pipeline landscape.

Drug overdoses occur when a person takes more than the medically recommended dose of a prescription or over-the-counter drug. It can be either accidental or intentional. Symptoms include sleepiness, confusion, chest pain, seizures, abdominal pain, nausea, vomiting, and diarrhea. Risk factors include age, gender, mental illness and history of overdose. Treatment includes antidote and activated charcoal.

Report Highlights

The publisher's Pharmaceutical and Healthcare latest pipeline guide Drug Overdose - Pipeline Review, H2 2020, provides comprehensive information on the therapeutics under development for Drug Overdose (Toxicology), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Drug Overdose (Toxicology) pipeline guide also reviews of key players involved in therapeutic development for Drug Overdose and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Pre-Registration, Filing rejected/Withdrawn, Phase II, Phase I, Preclinical, Discovery and Unknown stages are 3, 1, 2, 3, 5, 3 and 4 respectively. Similarly, the Universities portfolio in Preclinical stages comprises 2 molecules, respectively.

Drug Overdose (Toxicology) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from the publisher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content/sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Drug Overdose (Toxicology).
  • The pipeline guide reviews pipeline therapeutics for Drug Overdose (Toxicology) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Drug Overdose (Toxicology) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Drug Overdose (Toxicology) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Drug Overdose (Toxicology)

Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Drug Overdose (Toxicology).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Drug Overdose (Toxicology) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

Introduction
  • Report Coverage

Drug Overdose - Overview
Drug Overdose - Therapeutics Development
  • Pipeline Overview
  • Pipeline by Companies
  • Pipeline by Universities/Institutes
  • Products under Development by Companies
  • Products under Development by Universities/Institutes

Drug Overdose - Therapeutics Assessment
  • Assessment by Target
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type

Drug Overdose - Companies Involved in Therapeutics Development
  • Adamis Pharmaceuticals Corp
  • Amphastar Pharmaceuticals Inc
  • Crossject SA
  • Emergent BioSolutions Inc
  • Fab’entech SA
  • Icure Pharmaceutical Inc
  • Insys Therapeutics Inc
  • InterveXion Therapeutics LLC
  • Klaria Pharma Holding AB
  • Mucodel Pharma LLC
  • Opiant Pharmaceuticals Inc
  • Orexo AB
  • PledPharma AB
  • ResQ Pharma Inc
  • Vallon Pharmaceuticals Inc
  • Worphmed Srl

Drug Overdose - Drug Profiles
Antibody for Drug Overdose, Opioid Addiction and Poisoning - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

drinabant - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

IXTf-250 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

melatonin - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

nalmefene - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

nalmefene - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone hydrochloride - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone hydrochloride 1 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

naloxone. - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

OPNT-006 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

physostigmine - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

PP-100 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Small Molecule for Drug Overdose and Drug Toxicity - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Small Molecules for Alzheimer's Disease and Drug Overdose - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Small Molecules for Substance Abuse and Drug Overdose - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Vaccine for Drug Overdose - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Drug Overdose - Dormant ProjectsDrug Overdose - Discontinued Products
Drug Overdose - Product Development Milestones
  • Featured News & Press Releases
  • Aug 17, 2020: Emergent BioSolutions announces FDA approval of NARCAN (naloxone HCl) nasal spray shelf life extension to 36 months
  • Jul 01, 2020: Klaria Pharma initiates clinical program for Naloxone Alginate Film to prevent opioid overdose
  • Jun 30, 2020: Positive results from human PK study assessing Orexo’s intranasal nalmefene formulations for opioid overdose reversal
  • Jun 18, 2020: Adamis Pharmaceuticals announces publication of pharmacokinetic model suggesting that higher doses of naloxone are needed for successful resuscitation due to fentanyl overdose
  • Jun 05, 2020: Opiant Pharmaceuticals statement on U.S. District Court decision
  • May 27, 2020: Adamis Pharmaceuticals announces publication of pharmacokinetic study comparing ZIMHI to current 2 mg intramuscular dose of naloxone
  • May 18, 2020: Adamis Pharmaceuticals resubmits ZIMHI New Drug Application to FDA
  • Apr 23, 2020: Adamis Pharmaceuticals announces Publication demonstrating PET Scan results of higher dose Naloxone in Monkeys
  • Dec 19, 2019: Adamis Pharmaceuticals provides an update on ZIMHI
  • Dec 12, 2019: Opiant Pharmaceuticals announces contract extension of second tranche of approximately $2.4 million from Biomedical Advanced Research and Development Authority for development of OPNT003, Nasal Nalmefene, for the treatment of Opioid Overdose
  • Nov 26, 2019: FDA rejects Adamis’ NDA for high-dose naloxone against opioid overdose
  • Nov 18, 2019: Adamis Pharmaceuticals announces publication of comparative pharmacokinetics of community use naloxone formulations
  • Nov 04, 2019: Adamis Pharmaceuticals provides regulatory update for its higher dose Naloxone Pre-Filled Syringe
  • Oct 08, 2019: Adamis Pharmaceuticals announces presentation of ZIMHI data at IHV Scientific Meeting
  • Sep 26, 2019: Adamis Pharmaceuticals announces presentation pertaining to its high dose naloxone product candidate at IHV Scientific Meeting

Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact
  • Disclaimer

List of Tables
  • Number of Products under Development for Drug Overdose, H2 2020
  • Number of Products under Development by Companies, H2 2020
  • Number of Products under Development by Universities/Institutes, H2 2020
  • Products under Development by Companies, H2 2020
  • Products under Development by Companies, H2 2020 (Contd..1), H2 2020
  • Products under Development by Universities/Institutes, H2 2020
  • Number of Products by Stage and Target, H2 2020
  • Number of Products by Stage and Mechanism of Action, H2 2020
  • Number of Products by Stage and Route of Administration, H2 2020
  • Number of Products by Stage and Molecule Type, H2 2020
  • Drug Overdose - Pipeline by Adamis Pharmaceuticals Corp, H2 2020
  • Drug Overdose - Pipeline by Amphastar Pharmaceuticals Inc, H2 2020
  • Drug Overdose - Pipeline by Crossject SA, H2 2020
  • Drug Overdose - Pipeline by Emergent BioSolutions Inc, H2 2020
  • Drug Overdose - Pipeline by Fab’entech SA, H2 2020
  • Drug Overdose - Pipeline by Icure Pharmaceutical Inc, H2 2020
  • Drug Overdose - Pipeline by Insys Therapeutics Inc, H2 2020
  • Drug Overdose - Pipeline by InterveXion Therapeutics LLC, H2 2020
  • Drug Overdose - Pipeline by Klaria Pharma Holding AB, H2 2020
  • Drug Overdose - Pipeline by Mucodel Pharma LLC, H2 2020
  • Drug Overdose - Pipeline by Opiant Pharmaceuticals Inc, H2 2020
  • Drug Overdose - Pipeline by Orexo AB, H2 2020
  • Drug Overdose - Pipeline by PledPharma AB, H2 2020
  • Drug Overdose - Pipeline by ResQ Pharma Inc, H2 2020
  • Drug Overdose - Pipeline by Vallon Pharmaceuticals Inc, H2 2020
  • Drug Overdose - Pipeline by Worphmed Srl, H2 2020
  • Drug Overdose - Dormant Projects, H2 2020
  • Drug Overdose - Discontinued Products, H2 2020

List of Figures
  • Number of Products under Development for Drug Overdose, H2 2020
  • Number of Products under Development by Companies, H2 2020
  • Number of Products by Top 10 Targets, H2 2020
  • Number of Products by Stage and Top 10 Targets, H2 2020
  • Number of Products by Top 10 Mechanism of Actions, H2 2020
  • Number of Products by Stage and Top 10 Mechanism of Actions, H2 2020
  • Number of Products by Routes of Administration, H2 2020
  • Number of Products by Stage and Routes of Administration, H2 2020
  • Number of Products by Molecule Types, H2 2020
  • Number of Products by Stage and Molecule Types, H2 2020

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Adamis Pharmaceuticals Corp
  • Amphastar Pharmaceuticals Inc
  • Crossject SA
  • Emergent BioSolutions Inc
  • Fab’entech SA
  • Icure Pharmaceutical Inc
  • Insys Therapeutics Inc
  • InterveXion Therapeutics LLC
  • Klaria Pharma Holding AB
  • Mucodel Pharma LLC
  • Opiant Pharmaceuticals Inc
  • Orexo AB
  • PledPharma AB
  • ResQ Pharma Inc
  • Vallon Pharmaceuticals Inc
  • Worphmed Srl