Downstream Processing Market by Technique (Separation, Concentration, Purification), Product (Chromatography Column & Resin, Filter, Single use), Application (Mab Production), End User (Contract Manufacturing Organization) - Global Forecast to 2021

  • ID: 4189924
  • Report
  • Region: Global
  • 141 Pages
  • Markets and Markets
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Global Downstream Processing Market Projected to reach USD 22.03 Billion by 2021 from USD 10.32 Billion in 2016, at a CAGR of 16.4%

FEATURED COMPANIES

  • 3M Company
  • Boehringer Ingelheim
  • Danaher Corporation
  • Eppendorf AG
  • Finesse Solutions, Inc.
  • GE Healthcare
  • MORE

The global downstream processing market is projected to reach USD 22.03 billion by 2021 from USD 10.32 billion in 2016, at a CAGR of 16.4% from 2016 to 2021. Increasing demand for biopharmaceuticals and increasing R&D expenditure in the biopharmaceutical industry are the major factors driving the growth of the global downstream processing market.

Developing markets in Asia-Pacific such as Japan, China, India, South Korea, Taiwan, Australia, and Singapore are lucrative markets for downstream processing, rising geriatric population, growing per capita income, increasing investments in the healthcare industry by key market players, and increasing outsourcing services by various pharmaceutical companies from these countries are the major factors driving the growth of the downstream processing market in this region.

In this report, the downstream processing market is broadly segmented on the basis of technique, product, application, end user, and region. Based on application, the downstream processing market is classified into monoclonal antibody (mAbs) production, vaccine production, insulin production, immunoglobulin production, erythropoietin production, and other applications. The mAbs production segment is expected to grow at the fastest CAGR during the forecast period. This high growth is attributed to the increasing adoption of targeted immunotherapy and increasing number of U.S. FDA-cleared therapeutic monoclonal antibodies.

On the basis of technique, the market is segmented into purification, solid-liquid separation, and clarification/concentration. In 2016, the purification segment accounted for the largest share of the downstream processing market. The large share as well as the high growth of this segment is attributed to the growing need for highly pure biopharmaceutical products.

On the basis of product, the downstream processing market is segmented into chromatography columns and resins, filters, membrane adsorbers, single-use products, and other products. In 2016, the chromatography columns and resins segment accounted for the largest share of the downstream processing market. The constant need for newer and different types of columns and resins is likely to fuel market growth.

On the basis of end user, the downstream processing market is segmented into biopharmaceutical manufacturers and contract manufacturing organizations (CMOs). The contract manufacturing organizations (CMOs) segment is expected to grow at the highest CAGR during the forecast period.

New and innovative product launches was the dominant strategy adopted by key industry participants to increase their market share and cater to unmet needs. Thermo Fisher Scientific Inc. (U.S.), GE Healthcare (U.S.), Sartorius Stedim Biotech S.A. (France), Merck Millipore (Germany), and Danaher Corporation (U.S.) are some of the leading manufacturing companies that adopted this strategy.

Research Coverage:

From an insight perspective, this research report focuses on qualitative data, market size, and growth of various segments and subsegments, competitive landscape, and company profiles. The qualitative data covers various levels of industry analysis such as market dynamics (drivers, restraints, opportunities, and challenges). The report also offers market sizes and data on the growth of various segments of the industry. It focuses on emerging and high-growth segments, and high-growth regions. The competitive landscape covers growth strategies adopted by industry players in the last three years.

The company profiles comprise basic views on key players in the downstream processing market and the product portfolios, developments, and strategies adopted by market players to maintain and increase their market shares in the near future. The above-mentioned market research data, current market size, and forecast of future trends will help key players and new entrants to make the necessary decisions regarding product offerings, geographical focus, change in approach, R&D investments for innovations in products and technologies, and levels of output in order to remain successful.

Reasons to buy this report:

From an insight perspective, this research report focuses on various levels of analysis-industry analysis (industry trends) and company profiles, which together comprise and discuss the basic views on the competitive landscape; emerging and high-growth segments of the downstream processing market; high-growth regions; and market drivers, restraints, and opportunities.

The report provides insights on the following pointers:

  • Market Penetration: Comprehensive information on products offered by the top players in the downstream processing market
  • Product Development/Innovation: Detailed insights on the upcoming technologies, research & development activities, and new product launches in the downstream processing market
  • Market Development: Comprehensive information about lucrative emerging markets-the report analyzes the markets for downstream processing products across various regions
  • Market Diversification: Exhaustive information about new products, untapped geographies, and recent developments in the downstream processing market
  • Competitive Assessment: In-depth assessment of market ranking, strategies, products, and manufacturing capabilities of the leading players in the downstream processing market.
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FEATURED COMPANIES

  • 3M Company
  • Boehringer Ingelheim
  • Danaher Corporation
  • Eppendorf AG
  • Finesse Solutions, Inc.
  • GE Healthcare
  • MORE
1 Introduction

    1.1 Objectives of the Study

    1.2 Market Definition

           1.2.1 Markets Covered

           1.2.2 Years Considered for the Study

    1.3 Currency

    1.4 Limitations

    1.5 Stakeholders

2 Research Methodology

    2.1 Market Size Estimation

    2.2 Market Breakdown and Data Triangulation

           2.2.1 Key Data From Secondary Sources

           2.2.2 Key Data From Primary Sources

                    2.2.2.1 Key Industry Insights

    2.3 Assumptions for the Study

3 Executive Summary

4 Premium Insights

    4.1 Downstream Processing Market Snapshot, 2016 vs 2021

    4.2 Downstream Processing Market, By Product and Region

    4.3 Downstream Processing Market, By Technique, 2016 vs 2021 (USD Billion)

    4.4 Downstream Processing Market, By Application, 2016 vs 2021 (USD Billion)

    4.5 Downstream Processing Market, By End User, 2016 vs 2021 (USD Billion)

    4.6 Downstream Processing Market, By Region

5 Market Overview

    5.1 Introduction

           5.1.1 Drivers

                    5.1.1.1 Increasing Demand for Biopharmaceuticals

                    5.1.1.2 Increasing R&D Expenditure in Biopharmaceutical Companies

           5.1.2 Restraints

                    5.1.2.1 High Cost of Instruments

           5.1.3 Opportunities

                    5.1.3.1 Patent Expiry

           5.1.4 Challenges

                    5.1.4.1 Purification Bottleneck

                    5.1.4.2 Lack of Single-Use Options

                    5.1.4.3 Dearth of Skilled Professionals

6 Downstream Processing Market, By Technique

    6.1 Introduction

    6.2 Purification Techniques

           6.2.1 Gel Chromatography

           6.2.2 Ion Exchange Chromatography

           6.2.3 Affinity Chromatography

           6.2.4 Hydrophobic Interaction Chromatography

    6.3 Solid-Liquid Separation

           6.3.1 Filtration

                    6.3.1.1 Tangential Flow Filtration

                    6.3.1.2 Normal Flow Filtration

           6.3.2 Centrifugation

    6.4 Clarification/Concentration

7 Downstream Processing Market, By Product

    7.1 Introduction

    7.2 Chromatography Columns and Resins

    7.3 Filters

    7.4 Membrane Adsorbers

    7.5 Single-Use Products

    7.6 Other Products

8 Downstream Processing Market, By Application

    8.1 Introduction

    8.2 Monoclonal Antibody Production

    8.3 Vaccines Production

    8.4 Insulin Production

    8.5 Immunoglobulin Production

    8.6 Erythropoietin Production

    8.7 Other Applications

9 Downstream Processing Market, By End User

    9.1 Introduction

    9.2 Biopharmaceutical Manufacturers

    9.3 Contract Manufacturing Organizations

10 Downstream Processing Market, By Region

     10.1 Introduction

     10.2 North America

             10.2.1 U.S.

             10.2.2 Canada

     10.3 Europe

     10.4 Asia-Pacific

     10.5 Rest of the World

11 Competitive Landscape

     11.1 Overview

     11.2 Comparative Assessment of Key Market Players

     11.3 Competitive Situations and Trends

             11.3.1 Product Launches

             11.3.2 Acquisitions

             11.3.3 Expansions

             11.3.4 Collaborations

             11.3.5 Other Strategies

12 Company Profiles
(Overview, Products and Services, Financials, Strategy & Development) -

     12.1 Introduction

     12.2 Thermo Fisher Scientific Inc.

     12.3 GE Healthcare

     12.4 Sartorius Stedim Biotech S.A.

     12.5 Merck Millipore

     12.6 Danaher Corporation

     12.7 3M Company

     12.8 Boehringer Ingelheim

     12.9 Lonza Group AG

     12.10 Eppendorf AG

     12.11 Finesse Solutions, Inc.
  • Details on Overview, Products and Services, Financials, Strategy & Development Might Not Be Captured in Case of Unlisted Companies.
List of Tables

Table 1 Downstream Processing Market Size, By Technique, 2014-2021 (USD Million)
Table 2 Global Market Size for Purification Techniques, By Region, 2014-2021 (USD Million)
Table 3 North America: Market Size for Purification Techniques, By Country, 2014-2021 (USD Million)
Table 4 Global Market Size for Solid-Liquid Separation Techniques, By Region, 2014-2021 (USD Million)
Table 5 North America: Market Size for Solid-Liquid Separation Techniques, By Country, 2014-2021 (USD Million)
Table 6 Global Market Size for Clarification/Concentration Techniques, By Region, 2014-2021 (USD Million)
Table 7 North America: Market Size for Clarification/Concentration Techniques, By Country, 2014-2021 (USD Million)
Table 8 Global Market Size, By Product, 2014-2021 (USD Million)
Table 9 Global Market Size for Chromatography Columns and Resins, By Region, 2014-2021 (USD Million)
Table 10 North America: Market Size for Chromatography Columns and Resins, By Country, 2014-2021 (USD Million)
Table 11 Global Market Size for Filters, By Region, 2014-2021 (USD Million)
Table 12 North America: Market Size for Filters, By Country, 2014-2021 (USD Million)
Table 13 Global Market Size for Membrane Adsorbers, By Region, 2014-2021 (USD Million)
Table 14 North America: Market Size for Membrane Adsorbers, By Country, 2014-2021 (USD Million)
Table 15 Global Market Size for Single-Use Products, By Region, 2014-2021 (USD Million)
Table 16 North America: Market Size for Single-Use Products, By Country, 2014-2021 (USD Million)
Table 17 Global Market Size for Other Products, By Region, 2014-2021 (USD Million)
Table 18 North America: Market Size for Other Products, By Country, 2014-2021 (USD Million)
Table 19 Market Size, By Application, 2014-2021 (USD Million)
Table 20 an Indicative List of Blockbuster Mabs and Their Expiry Dates
Table 21 Global Market Size for Mab Production, By Region, 2014-2021 (USD Million)
Table 22 North America: Market Size for Monoclonal Antibody Production, By Country, 2014-2021 (USD Million)
Table 23 Global Market Size for Vaccine Production, By Region, 2014-2021 (USD Million)
Table 24 North America: Market Size for Vaccine Production, By Country, 2014-2021 (USD Million)
Table 25 Global Market Size for Insulin Production, By Region, 2014-2021 (USD Million)
Table 26 North America: Market Size for Insulin Production, By Country, 2014-2021 (USD Million)
Table 27 Global Market Size for Immunoglobulin Production, By Region, 2014-2021 (USD Million)
Table 28 North America: Market Size for Immunoglobulin Production, By Country, 2014-2021 (USD Million)
Table 29 Global Market Size for Erythropoietin Production, By Region, 2014-2021 (USD Million)
Table 30 North America: Market Size for Erythropoietin Production, By Country, 2014-2021 (USD Million)
Table 31 Global Market Size for Other Applications, By Region, 2014-2021 (USD Million)
Table 32 North America: Market Size for Other Applications, By Country, 2014-2021 (USD Million)
Table 33 Market Size, By End User, 2014-2021 (USD Million)
Table 34 Market Size for Biopharmaceutical Manufacturers, By Region, 2014-2021 (USD Million)
Table 35 North America: Market Size for Biopharmaceutical Manufacturers, By Country, 2014-2021 (USD Million)
Table 36 Market Size for Contract Manufacturing Organizations, By Region, 2014-2021 (USD Million)
Table 37 North America: Market Size for Contract Manufacturing Organizations, By Country, 2014-2021 (USD Million)
Table 38 Market Size, By Region, 2014-2021 (USD Million)
Table 39 North America: Market Size, By Country, 2014-2021 (USD Million)
Table 40 North America: Market Size, By Technique, 2014-2021 (USD Million)
Table 41 North America: Market Size, By Product, 2014-2021 (USD Million)
Table 42 North America: Market Size, By Application, 2014-2021 (USD Million)
Table 43 North America: Market Size, By End User, 2014-2021 (USD Million)
Table 44 U.S.: Market Size, By Technique, 2014-2021 (USD Million)
Table 45 U.S.: Market Size, By Product, 2014-2021 (USD Million)
Table 46 U.S.: Market Size, By Application, 2014-2021 (USD Million)
Table 47 U.S.: Market Size, By End User, 2014-2021 (USD Million)
Table 48 Canada: Market Size, By Technique, 2014-2021 (USD Million)
Table 49 Canada: Market Size, By Product, 2014-2021 (USD Million)
Table 50 Canada: Market Size, By Application, 2014-2021 (USD Million)
Table 51 Canada : Market Size, By End User, 2014-2021 (USD Million)
Table 52 Europe: Downstream Processing Market Size, By Technique, 2014-2021 (USD Million)
Table 53 Europe: Downstream Processing Market Size, By Product, 2014-2021 (USD Million)
Table 54 Europe: Downstream Processing Market Size, By Application, 2014-2021 (USD Million)
Table 55 Europe : Downstream Processing Market Size, By End User, 2014-2021 (USD Million)
Table 56 Asia-Pacific: Downstream Processing Market Size, By Technique, 2014-2021 (USD Million)
Table 57 Asia-Pacific: Downstream Processing Market Size, By Product, 2014-2021 (USD Million)
Table 58 Asia-Pacific: Downstream Processing Market Size, By Application, 2014-2021 (USD Million)
Table 59 Asia-Pacific: Downstream Processing Market Size, By End User, 2014-2021 (USD Million)
Table 60 RoW: Downstream Processing Market Size, By Technique, 2014-2021 (USD Million)
Table 61 RoW: Downstream Processing Market Size, By Product, 2014-2021 (USD Million)
Table 62 RoW: Downstream Processing Market Size, By Application, 2014-2021 (USD Million)
Table 63 RoW : Downstream Processing Market Size, By End User, 2014-2021 (USD Million)
Table 64 Product Launches, 2014-2016
Table 65 Acquisitions, 2014-2016
Table 66 Expansions, 2014-2016
Table 67 Collaborations, 2014-2016
Table 68 Other Strategies, 2014-2016

List of Figures

Figure 1 Downstream Processing Market Segmentation
Figure 2 Research Design
Figure 3 Market Size Estimation Methodology: Bottom-Up Approach
Figure 4 Market Size Estimation Methodology: Top-Down Approach
Figure 5 Breakdown of Primary Interviews: By Company Type, Designation, and Region
Figure 6 Market Data Triangulation Methodology
Figure 7 Downstream Processing Market, By Technique, 2016 vs 2021 (USD Billion)
Figure 8 Downstream Processing Market, By Product, 2016 vs 2021 (USD Billion)
Figure 9 Downstream Processing Market Size, By Application, 2016 vs 2021 (USD Billion)
Figure 10 Downstream Processing Market Size, By End User, 2016 vs 2021 (USD Billion)
Figure 11 Geographical Snapshot of the Downstream Processing Market
Figure 12 Increasing Demand for Biopharmaceuticals
Figure 13 Chromatography Columns and Resins Accounted for the Largest Market Share in 2016
Figure 14 The Purification Segment Dominated the Downstream Processing Techniques Market in 2016
Figure 15 Vaccine Production to Command Highest Share in the Downstream Processing Market in 2016
Figure 16 Biopharmaceutical Manufacturers Dominated the Downstream Manufacturing End Users Market in 2016
Figure 17 Asia-Pacific to Grow at the Highest Rate During the Forecast Period
Figure 18 Downstream Processing Market: Drivers, Restraints, Opportunities, & Challenges
Figure 19 Growth in Aging Population, By Country (2011-2030)
Figure 20 U.S.: Biologics Going Off-Patent in the Coming Years
Figure 21 Processes Followed in Downstream Processing
Figure 22 Purification Techniques Segment to Dominate the Downstream Processing Market During the Forecast Period
Figure 23 Chromatography Column and Resins Dominated the Downstream Processing Products Market in 2016
Figure 24 Vaccine Production Segment to Dominate the Market During the Forecast Period
Figure 25 Biopharmaceutical Manufacturers to Dominate the Downstream Processing End-User Market in 2016
Figure 26 Geographic Snapshot: APAC Will Be the Fastest-Growing Market for Downstream Processing During the Forecast Period
Figure 27 North American Downstream Processing Market Snapshot
Figure 28 Asia-Pacific Downstream Processing Market Snapshot
Figure 29 Companies Majorly Pursued the Strategy of Product Launches to Enhance Their Market Presence
Figure 30 Battle for Market Share: Product Launches-Key Growth Strategy Adopted By Market Players
Figure 31 Geographic Revenue Mix of Top Five Market Players
Figure 32 Thermo Fisher Scientific Inc.: Company Snapshot
Figure 33 GE Healthcare: Company Snapshot (2015)
Figure 34 Sartorius Stedim Biotech S.A.: Company Snapshot (2015)
Figure 35 Merck Millipore: Company Snapshot (2015)
Figure 36 Danaher Corporation: Company Snapshot (2015)
Figure 37 3M Company: Company Snapshot (2015)
Figure 38 Boehringer Ingelheim: Company Snapshot (2015)
Figure 39 Lonza Group AG: Company Snapshot (2015)
Figure 40 Eppendorf AG: Company Snapshot (2015)
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  • 3M Company
  • Boehringer Ingelheim
  • Danaher Corporation
  • Eppendorf AG
  • Finesse Solutions, Inc.
  • GE Healthcare
  • Lonza Group AG
  • Merck Millipore
  • Sartorius Stedim Biotech S.A.
  • Thermo Fisher Scientific Inc.
Note: Product cover images may vary from those shown
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Note: Product cover images may vary from those shown
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