Biomaterials for Oral and Dental Tissue Engineering examines the combined impact of materials, advanced techniques and applications of engineered oral tissues. With a strong focus on hard and soft intraoral tissues, the book looks at how biomaterials can be manipulated and engineered to create functional oral tissue for use in restorative dentistry, periodontics, endodontics and prosthodontics. Covering the current knowledge of material production, evaluation, challenges, applications and future trends, this book is a valuable resource for materials scientists and researchers in academia and industry.
The first set of chapters reviews a wide range of biomaterial classes for oral tissue engineering. Further topics include material characterization, modification, biocompatibility and biotoxicity. Part Two reviews strategies for biomaterial scaffold design, while chapters in parts three and four review soft and hard tissues.
- Connects materials science with restorative dentistry
- Focuses on the unique field of intraoral tissues
- Highlights long-term biocompatibility and toxicity of biomaterials for engineered oral tissues
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Part I: Biomaterials for Oral and Dental Tissue Engineering 1. Introduction to Oral and Dental Tissue Engineering 2. Bioactive Glasses and Calcium Phosphates 3. Polymers for Oral and Dental Tissue Engineering 4. Hydrogels in Craniofacial Tissue Engineering 5. Dental Biocomposites 6. Surface Modification of Dental Implants 7. Characterization of Biomaterials 8. Biocompatibility of Dental Biomaterials 9. Processing and Preservation of Biomaterials and Regulatory Issues
Part II: Tissue Engineering Strategies 10. Specific Considerations in Scaffold Design for Oral Tissue Engineering 11. Stem Cells from Oral and Maxillofacial Tissues 12. Bioreactor Design for Oral and Dental Tissue Engineering 13. Growth Factors for Oral and Maxillofacial Regeneration Applications
Part III: Oral and Dental Soft Tissue Engineering 14. Oral Mucosa Tissue Engineering 15. Tissue Engineered Models of Oral Soft Tissue Diseases 16. Periodontal Soft Tissue Reconstruction 17. Layered Scaffolds for Periodontal Regeneration 18. Dental Pulp Tissue Engineering and Regenerative Endodontic Therapy 19. Oral Nerve Tissue Repair and Regeneration 20. Tissue Engineering of Salivary Glands 21. Facial Muscle Tissue Engineering 22. Vascularization
Part IV: Oral and Dental Hard Tissue Engineering 23. Bone Tissue Engineering in Maxillofacial Region 24. Periodontal and Peri-implant Hard Tissue Regeneration 25. Regeneration Concerns in Cartilage and Craniofacial Defects 26. Craniofacial Surgery, Orthodontics and Tissue Engineering 27. Tooth Tissue Engineering 28. Pharmacological Agents for Bone Remodelling: An Experimental Approach
Lobat Tayebi is an Associate Professor and Director of Research at Marquette University School of Dentistry. She received her PhD from University of California-Davis in 2011. She is a researcher in materials and regenerative medicine with multiple patents in the field. Her publication list comprises of more than 115 peer-reviewed articles including papers in Nature Materials and Advanced Materials. Her current research activities cover projects in smart materials, interfacial hard/soft tissue expansion, growth factor delivery, vascularization and stem cell seeding in patient specific 3D-bioprinted scaffolds, treatment of complex multi-tissue oral and craniomaxillofacial defects, and preservation of oral tissues. She enjoys interdisciplinary projects and has genuine believe in the effectiveness of multidisciplinary research.
Keyvan Moharamzadeh is a Senior Clinical Lecturer and Honorary Consultant in Restorative Dentistry at the University of Sheffield, United Kingdom. He is a registered specialist in Prosthodontics, Periodontics, Endodontics and Restorative Dentistry and has been closely involved with undergraduate and postgraduate teaching and research at the School of Clinical Dentistry. He is leading multidisciplinary internationally recognised research in the field of Dental Biomaterials and Tissue Engineering and has extensively published in the literature and given numerous presentations in the national and international conferences. His research activities comprise tissue engineering; biocompatibility of dental biomaterials; synthesis and analysis of polymers and composites in dentistry; and physical and optical properties of dental materials.