Environmental Causes and Prevention Measures for Alzheimer's Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures. This book will generate excitement and interest among neuroscientists, medical practitioners and other biomedical researchers.
- Emphasizes the history and epidemiology of Alzheimer's disease, highlighting its epidemic proportions in developed countries
- Discusses data on new environmental factors in developed countries
- Provides prevention measures to potentially reduce Alzheimer's rates through diet
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1. Introduction 2. A Little Background on Dementia and Alzheimer's Disease 3. Interesting and Important Historical and Demographic Facts About the Epidemic of Alzheimer's Disease Pointing to Environmental Intoxicants Causing the Epidemic 4. Candidate Environmental Factors for the Alzheimer's Epidemic Part 1: The Metals
Aluminum, Lead, Mercury, Zinc, Iron, and Copper 5. Candidate Environmental Factors for the Alzheimer's Epidemic Part 2: Diet and Other Life Style Factors 6. Identification of Copper-2, and Copper in General as Major Environmental Intoxicants in the Alzheimer's Epidemic: The Copper Hypothesis 7. Background on Copper, Including Why Copper-2 is so Specifically Neurotoxic 8. Inorganic Copper, or Copper-2, Ingestion as a Major Causal Factor for Alzheimer's Disease
The Web of Evidence 9. Increased Copper Absorption Resulting from Dietary Changes in Developed Countries as Another Causal Factor in the Alzheimer's Disease Epidemic 10. The Copper Hypothesis Fits Nicely with Known Risk Factors and Theories of Alzheimer's Disease Causation 11. Prevention Measures Action Items: Two Simple Steps to Eliminate Ingestion of Copper-2, and Dietary Changes to Reduce Copper Absorption 12. Failures: What the Government Hasn't Done to Ensure Healthy Drinking Water and Nontoxic Multimineral/Multivitamin Pills 13. Treatment of Alzheimer's Disease 14. Summary and Conclusions
Dr. George Brewer is a recognized world expert on all aspects of copper, but also has expertise in zinc and other micronutrients. He worked for over 30 years on the inherited disease of copper toxicity, Wilson's disease. He has published over 100 peer-reviewed papers on the topic and developed two new therapies for the disease: zinc and tetrathiomolybdate. Due to his research, zinc was approved for Wilson's disease by the FDA in 1997 and is now the treatment of choice for maintenance therapy. Over the last decade he has been working on Alzheimer's disease; his research has demonstrated that Alzheimer's patients are zinc-deficient and benefit from zinc therapy. Dr. Brewer has developed a new zinc formulation that is non-irritating and can be taken once daily. Over his career he has published over 430 papers and has written and edited numerous books.