PharmaPoint: Rheumatoid Arthritis - Global Drug Forecast and Market Analysis to 2025

  • ID: 4256785
  • Report
  • Region: Global
  • 403 pages
  • GlobalData
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  • Eli Lilly
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PharmaPoint: Rheumatoid Arthritis - Global Drug Forecast and Market Analysis to 2025

Summary

Rheumatoid arthritis (RA) is a chronic autoimmune disease which causes inflammation and deformity of the joints. It affects over six million individuals in the 8MM covered in this report (US, France, Germany, Italy, Spain, UK, Japan, and Australia) and this prevalence is expected to grow to just shy of 7 million individuals by 2025. The anti-TNFs have been effective in treating the signs and symptoms of RA and inhibiting progression to erosive bone disease.

The RA market in the 8MM is expected to grow at a Compound Annual Growth Rate (CAGR) of 3.9% during the forecast period, from 2015 sales of $19.5 billion to sales of $28.5 billion in 2025.

The major drivers of growth in the global RA market during the forecast period are:
- An increase in the prevalent cases of RA in all the markets, in part, due to an aging population.
- The launch and continued uptake of biosimilars for all established biologics on the RA market (infliximab, etanercept, adalimumab, golimumab, certolizumab pegol, tocilizumab, abatacept, and rituximab) in all the markets covered in the report, which is expected to lead to an increase in patient volume by making treatments more accessible.
- The early diagnosis and treatment of patients with RA to limit disease progression.

The RA market is dominated by Big Pharma, and most of the compounds in late-stage development are backed by a major pharmaceutical company. The major players in the RA market have extensive portfolios, and may enter into Phase I buyouts and partnerships at very early stages. It is especially common for these companies to form an early partnership for development in the Japanese market.

Biosimilars for all established biologics are expected to launch in all 8MM by 2025, with the exception of etanercept in the US and certolizumab in Japan. Overall, the market share of biosimilars will account for 23% of the 8MM RA market in 2025. It is this potential segment of the RA market that Big Pharma companies such as Pfizer and Amgen have realized, and as such are pursuing their own biosimilar development programs.

The report "PharmaPoint: Rheumatoid Arthritis - Global Drug Forecast and Market Analysis to 2025" provides an overview of rheumatoid arthritis (RA), including etiology, pathophysiology, and country-specific diagnosis and treatment recommendations.

In depth, this report provides the following analysis:
- Provides comprehensive data split across different phases and emerging trends, specifically JAK inhibitors (such as Eli Lilly/Incyte’s Olumiant (baricitinib), novel biologics (such as AstraZeneca-MedImmune’s mavrilimumab), and biosimilars (such as Celltrion/Hospira/Pfizer’s Inflectra/Remsima, Samsung Bioepis/Biogen/Merck’s Flixabi and Benepali, Sandoz’s Erelzi, and Amgen’s Amjevita).
- Provides annualized RA market revenue, annual cost of therapy and treatment usage pattern data from 2015 and forecast for ten years to 2025.
- Analysis of strategic competitor assessment, market characterization, unmet needs, clinical trial mapping, and implications for the RA biologics and biosimilars markets.
- Analysis of the current and future market competition in the global RA market. Insightful review of the key industry and governmental drivers, restraints and challenges.

Companies mentioned in this report: AbbVie, Pfizer, Amgen, Johnson & Johnson, Eli Lilly, Bristol-Myers Squibb, UCB, Roche, GlaxoSmithKline, Novartis, Sanofi, AstraZeneca-MedImmune, Astellas, Daiichi Sankyo, Samsung Bioepis, Sandoz.

Scope
- Overview of rheumatoid arthritis (RA), including etiology, pathophysiology, and country-specific diagnosis and treatment recommendations.
- Annualized RA market revenue, annual cost of therapy and treatment usage pattern data from 2015 and forecast for ten years to 2025.
- Key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping, and implications for the RA biologics and biosimilars markets.
- Pipeline analysis: comprehensive data split across different phases and emerging trends, specifically JAK inhibitors (such as Eli Lilly/Incyte’s Olumiant (baricitinib), novel biologics (such as AstraZeneca-MedImmune’s mavrilimumab), and biosimilars (such as Celltrion/Hospira/Pfizer’s Inflectra/Remsima, Samsung Bioepis/Biogen/Merck’s Flixabi and Benepali, Sandoz’s Erelzi, and Amgen’s Amjevita).
- Analysis of the current and future market competition in the global RA market. Insightful review of the key industry and governmental drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.

Reasons to buy

The report will enable you to:
- Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
- Develop business strategies by understanding the trends shaping and driving the RA market.
- Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the global RA market in the future.
- Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
- Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
- Track drug sales in the eight major RA markets from 2015-2025.
- Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments and strategic partnerships.
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FEATURED COMPANIES

  • AbbVie
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1 Table of Contents
2 Introduction
2.1 Catalyst
2.2 Related Reports
2.3 Upcoming Related Reports
3 Disease Overview
3.1 Etiology and Pathophysiology
3.1.1 Etiology
3.1.2 Pathophysiology
3.2 Symptoms
3.3 Prognosis
3.4 Quality of Life
4 Epidemiology
4.1 Disease Background
4.2 Risk Factors and Comorbidities
4.3 Global Trends
4.3.1 Diagnosed Incidence
4.3.2 Prevalence
4.4 Forecast Methodology
4.4.1 Sources Used
4.4.2 Forecast Assumptions and Methods
4.4.3 Sources Not Used
4.5 Epidemiological Forecast for RA (2015-2025)
4.5.1 Diagnosed Incident Cases
4.5.2 Diagnosed Prevalent Cases
4.5.3 Total Prevalent Cases
4.6 Discussion
4.6.1 Epidemiological Forecast Insight
4.6.2 Limitations of the Analysis
4.6.3 Strengths of the Analysis
5 Disease Management
5.1 Diagnosis and Treatment Overview
5.1.1 Diagnosis
5.1.2 Treatment Guidelines
5.1.3 Leading Prescribed Drugs for the Treatment of RA
5.1.4 Clinical Practice
5.2 US
5.3 France
5.4 Germany
5.5 Italy
5.6 Spain
5.7 UK
5.8 Japan
5.9 Australia
6 Competitive Assessment
6.1 Overview
6.2 Product Profiles - Major Brands
6.2.1 Enbrel (etanercept)
6.2.2 Humira (adalimumab)
6.2.3 Remicade (infliximab)
6.2.4 Simponi (golimumab)
6.2.5 Cimzia (certolizumab pegol)
6.2.6 Orencia (abatacept)
6.2.7 Actemra/RoActemra (tocilizumab)
6.2.8 Rituxan/MabThera (rituximab)
6.2.9 Inflectra/Remsima (infliximab biosimilar)
6.2.10 Flixabi (infliximab biosimilar)
6.2.11 Benepali (etanercept biosimilar)
6.2.12 Erelzi (etanercept biosimilar)
6.2.13 Amjevita (adalimumab biosimilar)
6.2.14 Xeljanz (tofacitinib)
6.2.15 Iguratimod/T-614
6.2.16 Methotrexate (Numerous Brands)
6.3 Biosimilars Assessment
6.3.1 Introduction
6.3.2 Biosimilars in the Immunology Community
6.3.3 By the Numbers: Biosimilars in Development
6.3.4 The Impact of Biosimilars Is Being Felt Throughout the Pharmaceutical Industry
6.3.5 Uptake of Biosimilars for RA Is Expected to Vary by Market
6.4 Other Therapies
7 Unmet Needs and Opportunities
7.1 Overview
7.2 Development of Cost-Effective Therapies
7.2.1 Unmet Need
7.2.2 Gap Analysis
7.2.3 Opportunity
7.3 Biomarkers to Predict Responsiveness to Therapy
7.3.1 Unmet Need
7.3.2 Gap Analysis
7.3.3 Opportunity
7.4 Early Diagnosis of RA
7.4.1 Unmet Need
7.4.2 Gap Analysis
7.4.3 Opportunity
7.5 Personalized Treatment Approach
7.5.1 Unmet Need
7.5.2 Gap Analysis
7.5.3 Opportunity
8 Pipeline Assessment
8.1 Overview
8.2 Clinical Trial Mapping
8.2.1 Clinical Trials by Class
8.3 Promising Drugs in Clinical Development
8.3.1 Sarilumab
8.3.2 Sirukumab
8.3.3 Clazakizumab
8.3.4 Vobarilizumab (ALX-0016)
8.3.5 Mavrilimumab
8.3.6 Pralia (denosumab)
8.3.7 Olumiant (baricitinib)
8.3.8 Peficitinib
8.3.9 Filgotinib
8.3.10 Upadacitinib
8.3.11 Piclidenoson
8.4 Other Drugs in Development
9 Current and Future Players
9.1 Trends in Corporate Strategy
9.2 Company Profiles
9.2.1 AbbVie
9.2.2 Pfizer
9.2.3 Amgen
9.2.4 Johnson & Johnson
9.2.5 Eli Lilly
9.2.6 Bristol-Myers Squibb
9.2.7 UCB
9.2.8 Roche
9.2.9 GlaxoSmithKline
9.2.10 Sanofi
9.2.11 AstraZeneca- MedImmune
9.2.12 Astellas
9.2.13 Daiichi Sankyo
9.2.14 Samsung Bioepis
9.2.15 Sandoz
10 Market Outlook
10.1 Global Markets
10.1.1 Forecast
10.1.2 Drivers and Barriers - Global Issues
10.2 US
10.2.1 Forecast
10.2.2 Key Events
10.2.3 Drivers and Barriers
10.3 5EU
10.3.1 Forecast
10.3.2 Key Events
10.3.3 Drivers and Barriers
10.4 Japan
10.4.1 Forecast
10.4.2 Key Events
10.4.3 Drivers and Barriers
10.5 Australia
10.5.1 Forecast
10.5.2 Key Events
10.5.3 Drivers and Barriers
11 Appendix
11.1 Bibliography
11.2 Abbreviations
11.3 Methodology
11.4 Forecasting Methodology
11.4.1 Diagnosed RA Patients
11.4.2 Percentage of Drug-Treated Patients
11.4.3 Drugs Included in Each Therapeutic Class
11.4.4 Launch and Patent Expiry Dates
11.4.5 General Pricing Assumptions
11.4.6 Individual Drug Assumptions
11.4.7 Generic and Biosimilar Erosion
11.4.8 Pricing of Pipeline Agents
11.5 Primary Research - KOLs Interviewed for This Report
11.6 Primary Research - Prescriber Survey
11.7 About the Authors
11.7.1 Analyst
11.7.2 Therapy Area Director
11.7.3 Epidemiologist
11.7.4 Global Director of Therapy Analysis and Epidemiology

List of Tables
Table 1: Symptoms of RA
Table 2: Risk Factors and Comorbidities of RA
Table 3: 1987 ACR Diagnostic Criteria for RA
Table 4: 8MM, Sources Used to Forecast the Diagnosed Incident Cases of RA
Table 5: 8MM, Sources Used to Forecast the Total Prevalent Cases of RA
Table 6: 8MM, Sources Used to Forecast the Diagnosed Prevalent Cases of RA
Table 7: 8MM, Sources Used to Forecast Severity Segmentation of the Diagnosed Prevalent Cases of RA
Table 8: 8MM, Sources Not Used in the Epidemiological Analysis of RA
Table 9: 8MM, Diagnosed Incident Cases of RA, Ages =18 Years, Both Sexes, N, Selected Years 2015-2025
Table 10: 8MM, Age-Specific Diagnosed Incident Cases of RA, Both Sexes, N (Row %), 2015
Table 11: 8MM, Sex-Specific Diagnosed Incident Cases of RA, Ages =18 Years, N (Row %), 2015
Table 12: 8MM, Diagnosed Prevalent Cases of RA, Ages =18 Years, Both Sexes, N, Selected Years 2015-2025
Table 13: 8MM, Age-Specific Diagnosed Prevalent Cases of RA, Both Sexes, N (Row %), 2015
Table 14: 8MM, Sex-Specific Diagnosed Prevalent Cases of RA, Ages =18 Years, N (Row %), 2015
Table 15: 8MM, Total Prevalent Cases of RA, Ages =18 Years, Both Sexes, N, Selected Years 2015-2025
Table 16: 8MM, Age-Specific Total Prevalent Cases of RA, Both Sexes, N (Row %), 2015
Table 17: 8MM, Sex-Specific Total Prevalent Cases of RA, Ages =18 Years, N (Row %), 2015
Table 18: 1987 ACR Diagnostic Criteria for RA
Table 19: 2010 ACR/EULAR Diagnostic Criteria for RA
Table 20: Treatment Guidelines for RA Used by Each Country in the 8MM
Table 21: ACR 2015 Criteria for RA Remission and Low/Moderate/High Disease Activity
Table 22: EULAR 2013 Criteria for RA Remission
Table 23: Most-Prescribed Biologics for RA (After csDMARDs) in the Global Markets, 2015
Table 24: RA Treatment Country Profile - US
Table 25: RA Treatment Country Profile - France
Table 26: RA Treatment Country Profile - Germany
Table 27: RA Treatment Country Profile - Italy
Table 28: RA Treatment Country Profile - Spain
Table 29: RA Treatment Country Profile - UK
Table 30: RA Treatment Country Profile - Japan
Table 31: RA Treatment Country Profile - Australia
Table 32: Leading Branded Treatments for RA, 2016
Table 33: Product Profile - Enbrel
Table 34: 10-Year, Open-Label Safety and Efficacy Trial of Enbrel: Efficacy Results at 11 Years for Completers
Table 35: 10-Year, Open-Label Safety and Efficacy Trial of Enbrel: Overall Safety Results
Table 36: Enbrel SWOT Analysis, 2016
Table 37: Product Profile - Humira
Table 38: Humira SWOT Analysis, 2016
Table 39: Product Profile - Remicade
Table 40: Remicade SWOT Analysis, 2016
Table 41: Product Profile - Simponi
Table 42: Simponi SWOT Analysis, 2016
Table 43: Product Profile - Cimzia
Table 44: Cimzia SWOT Analysis, 2016
Table 45: Product Profile - Orencia
Table 46: Orencia SWOT Analysis, 2016
Table 47: Product Profile - Actemra
Table 48: Actemra SWOT Analysis, 2016
Table 49: Product Profile - Rituxan
Table 50: Rituxan SWOT Analysis, 2016
Table 51: Product Profile - Inflectra/Remsima
Table 52: Inflectra/Remsima SWOT Analysis, 2016
Table 53: Product Profile - Flixabi
Table 54: Flixabi SWOT Analysis, 2016
Table 55: Product Profile - Benepali
Table 56: Benepali SWOT Analysis, 2016
Table 57: Product Profile - Erelzi
Table 58: Erelzi SWOT Analysis, 2016
Table 59: Product Profile - Amjevita
Table 60: Amjevita SWOT Analysis, 2016
Table 61: Product Profile - Xeljanz
Table 62: ORAL Standard ACR20 Responses for Tofacitinib vs. Humira and Placebo at Month 6
Table 63: ORAL Step ACR20, 50, and 70 Responses for Xeljanz vs. Placebo at Month 6
Table 64: Xeljanz SWOT Analysis, 2016
Table 65: Product Profile - Iguratimod
Table 66: Iguratimod SWOT Analysis, 2016
Table 67: Product Profile - MTX
Table 68: MTX SWOT Analysis, 2016
Table 69: Marketed and Pipeline Biosimilars for RA, 2016
Table 70: Biosimilar Legislations Across the 8MM
Table 71: Physician Uptake of Biosimilar Products for RA Across the 8MM, 2016
Table 72: Summary of Minor Therapeutic Drug Classes Used to Treat RA, 2016
Table 73: Unmet Needs and Opportunities in RA, 2016
Table 74: Comparison of Therapeutic Drug Classes in Development for RA, 2016
Table 75: Product Profile - Sarilumab
Table 76: MOBILITY Study Part, A, Results for Sarilumab at Week 12
Table 77: MOBILITY Study Part B, Results for Sarilumab at Week 52
Table 78: Safety Results of the Sarilumab Phase III SARIL-RA-ASCERTAIN Trial
Table 79: Laboratory Results of Sarilumab Phase III SARIL-RA-ASCERTAIN Trial
Table 80: Sarilumab SWOT Analysis, 2016
Table 81: Product Profile - Sirukumab
Table 82: SIRROUND-D Study Results for Sirukumab
Table 83: Sirukumab SWOT Analysis, 2016
Table 84: Product Profile - Clazakizumab
Table 85: Phase IIb Study of Clazakizumab: ACR Responses After 12 Weeks
Table 86: Phase IIb Study of Clazakizumab: ACR Responses After 24 Weeks
Table 87: Clazakizumab SWOT Analysis, 2016
Table 88: Product Profile - Vobarilizumab
Table 89: Phase IIb Study of Vobarilizumab: Efficacy Results for ITT Population at Week 12
Table 90: Vobarilizumab SWOT Analysis, 2016
Table 91: Product Profile - Mavrilimumab
Table 92: EARTH-EXPLORER 2 Results for Mavrilimumab at 24 Weeks
Table 93: EARTH-EXPLORER 2 Results for Mavrilimumab at 24 Weeks
Table 94: Mavrilimumab SWOT Analysis, 2016
Table 95: Product Profile - Denosumab
Table 96: Denosumab SWOT Analysis, 2016
Table 97: Product Profile - Baricitinib
Table 98: Phase III RA-BEAM Study Results for Baricitinib at Week 12
Table 99: Phase III RA-BEAM Study Results for Baricitinib at Week 24
Table 100: Phase III RA-BEACON Study Results for Baricitinib at Week 12 and Week 24
Table 101: Phase III RA-BUILD Study Results for Baricitnib at Week 12 and Week 24
Table 102: Baricitinib SWOT Analysis, 2016
Table 103: Product Profile - Peficitinib
Table 104: Peficitinib SWOT Analysis, 2016
Table 105: Product Profile - Filgotinib
Table 106: DARWIN I Study Results for Filgotinib at Week 12
Table 107: DARWIN I Study Results for Filgotinib at Week 24
Table 108: DARWIN II Study Results for Filgotinib at Week 12
Table 109: DARWIN II Study Results for Filgotinib at Week 24
Table 110: Filgotinib SWOT Analysis, 2016
Table 111: Product Profile - Upadacitinib
Table 112: Upadacitinib Phase IIb BALANCE-I Trial, ACR Responses at Week 12
Table 113: Upadacitinib Phase IIb BALANCE-II Trial, ACR Responses at Week 12
Table 114: Upadacitinib SWOT Analysis, 2016
Table 115: Product Profile - Piclidenoson
Table 116: Piclidenoson SWOT Analysis, 2016
Table 117: Drugs in Phase II of Development for RA, 2016
Table 118: Key Companies in the RA Market, 2016
Table 119: AbbVie’s RA Portfolio Assessment, 2016
Table 120: AbbVie SWOT Analysis in RA, 2015-2025
Table 121: Pfizer’s RA Portfolio Assessment, 2016
Table 122: Pfizer SWOT Analysis in RA, 2015-2025
Table 123: Amgen’s RA Portfolio Assessment, 2016
Table 124: Amgen SWOT Analysis in RA, 2015-2025
Table 125: J&J’s RA Portfolio Assessment, 2016
Table 126: J&J SWOT Analysis in RA, 2015-2025
Table 127: Eli Lilly’s RA Portfolio Assessment, 2016
Table 128: Eli Lilly SWOT Analysis in RA, 2015-2025
Table 129: BMS’ RA Portfolio Assessment, 2016
Table 130: BMS SWOT Analysis in RA, 2015-2025
Table 131: UCB’s RA Portfolio Assessment, 2016
Table 132: UCB SWOT Analysis in RA, 2015-2025
Table 133: Roche’s RA Portfolio Assessment, 2016
Table 134: Roche SWOT Analysis in RA, 2015-2025
Table 135: GSK’s RA Portfolio Assessment, 2016
Table 136: GSK SWOT Analysis in RA, 2015-2025
Table 137: Sanofi’s RA Portfolio Assessment, 2016
Table 138: Sanofi SWOT Analysis in RA, 2015-2025
Table 139: AstraZeneca/MedImmune’s RA Portfolio Assessment, 2016
Table 140: AstraZeneca/MedImmune SWOT Analysis in RA, 2015-2025
Table 141: Astellas’ RA Portfolio Assessment, 2016
Table 142: Astellas SWOT Analysis in RA, 2015-2025
Table 143: Daiichi Sankyo’s RA Portfolio Assessment, 2016
Table 144: Daiichi Sankyo SWOT Analysis in RA, 2015-2025
Table 145: Samsung Bioepis’ RA Portfolio Assessment, 2016
Table 146: Samsung Bioepis’ SWOT Analysis in RA, 2015-2025
Table 147: Sandoz’s RA Portfolio Assessment, 2016
Table 148: Sandoz’s SWOT Analysis in RA, 2015-2025
Table 149: Global RA Market - Drivers and Barriers, 2015-2025
Table 150: Key Events Impacting Sales for RA in the US, 2015-2025
Table 151: RA Market in the US - Drivers and Barriers, 2015-2025
Table 152: Key Events Impacting Sales for RA in the 5EU, 2015-2025
Table 153: RA Market in 5EU - Drivers and Barriers, 2015-2025
Table 154: Key Events Impacting Sales for RA in Japan, 2015-2025
Table 155: RA Market in Japan - Drivers and Barriers, 2013-2023
Table 156: Key Events Impacting Sales for RA in Australia, 2015-2025
Table 157: RA Market in Australia - Drivers and Barriers, 2013-2023
Table 158: 8MM, Key Launch Dates of RA Products
Table 159: 8MM, Key Patent Expiries of RA Products
Table 160: High-Prescribing Physicians (non-KOLs) Surveyed, By Country

List of Figures
Figure 1: Normal Synovial Joint and Synovial Joint with RA
Figure 2: Cellular and Cytokine Targets for the Current RA Drugs
Figure 3: 8MM, Diagnosed Incident Cases of RA, Ages =18 Years, Both Sexes, N, 2015-2025
Figure 4: 8MM, Age-Specific Diagnosed Incident Cases of RA, Both Sexes, N, 2015
Figure 5: 8MM, Sex-Specific Diagnosed Incident Cases of RA, Ages =18 Years, N, 2015
Figure 6: 8MM, Age-Standardized Diagnosed Incidence of RA, Ages =18 Years, Cases per 100,000 Population, 2015
Figure 7: 8MM, Diagnosed Prevalent Cases of RA, Ages =18 Years, Both Sexes, N, Selected Years 2015-2025
Figure 8: 8MM, Age-Specific Diagnosed Prevalent Cases of RA, Both Sexes, N, 2015
Figure 9: 8MM, Sex-Specific Diagnosed Prevalent Cases of RA, Ages =18 Years, N, 2015
Figure 10: 8MM, Age-Standardized Diagnosed Prevalence of RA, Ages =18 Years, %, 2015
Figure 11: 8MM, Diagnosed Prevalent Cases of RA by Severity, Both Sexes, Ages =18 Years, N, 2015
Figure 12: 8MM, Total Prevalent Cases of RA, Ages =18 Years, Both Sexes, N, Selected Years 2015-2025
Figure 13: 8MM, Age-Specific Total Prevalent Cases of RA, Both Sexes, N, 2015
Figure 14: 8MM, Sex-Specific Total Prevalent Cases of RA, Ages =18 Years, N, 2015
Figure 15: 8MM, Age-Standardized Total Prevalence of RA, Ages =18 Years, N, 2015
Figure 16: Disease Management Flowchart for Early RA - ACR 2015
Figure 17: Disease Management Flowchart for Established RA - ACR 2015
Figure 18: Flowchart for the Management of RA - EULAR 2013
Figure 19: Biosimilar Prescribing Habits in RA Across the 8MM, 2016
Figure 20: RA Clinical Trials by Drug Class, 2016
Figure 21: RA Phase II-III Pipeline, 2016
Figure 22: Competitive Assessment of Late-Stage Pipeline Agents in RA, 2015-2025
Figure 23: Clinical and Commercial Positioning of Sarilumab
Figure 24: Clinical and Commercial Positioning of Sirukumab
Figure 25: Clinical and Commercial Positioning of Clazakizumab
Figure 26: Clinical and Commercial Positioning of Vobarilizumab
Figure 27: Clinical and Commercial Positioning of Mavrilimumab
Figure 28: Clinical and Commercial Positioning of Denosumab in RA
Figure 29: Clinical and Commercial Positioning of Baricitinib
Figure 30: Clinical and Commercial Positioning of Peficitinib
Figure 31: Clinical and Commercial Positioning of Filgotinib
Figure 32: Clinical and Commercial Positioning of Upadacitinib
Figure 33: Clinical and Commercial Positioning of Piclidenoson
Figure 34: Company Portfolio Gap Analysis in RA, 2015-2025
Figure 35: Global Sales for RA by Region, 2015-2025
Figure 36: Sales for RA in the US by Drug Class, 2015-2025
Figure 37: Sales for RA in the 5EU by Drug Class, 2015-2025
Figure 38: Sales for RA in Japan by Drug Class, 2015-2025
Figure 39: Sales for RA in Australia by Drug Class, 2015-2025
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  • AbbVie
  • Pfizer
  • Amgen
  • Johnson & Johnson
  • Eli Lilly
  • Bristol-Myers Squibb
  • UCB
  • Roche
  • GlaxoSmithKline
  • Sanofi
  • AstraZeneca- MedImmune
  • Astellas
  • Daiichi Sankyo
  • Samsung Bioepis
  • Sandoz
Note: Product cover images may vary from those shown
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