Methods in Tau Cell Biology, Vol 141. Methods in Cell Biology

  • ID: 4288432
  • Book
  • 342 Pages
  • Elsevier Science and Technology
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Methods in Tau Cell Biology, Volume 141, the latest release in the Methods in Cell Biology series, looks at methods involved in tau cell biology. Edited by leaders in the field, this volume provides proven, state-of-art techniques and relevant historical background and theory that aids researchers with tactics for efficient design and effective implementation of experimental methodologies. Topics of note in this updated volume include sections on Recombinant tau expression and purification, In vitro MT dynamics and MT ends, Methods related to investigating tau structure and MT bundling, Neurite outgrowth and retraction, and Methods related to studying tau fragmentation.

  • Covers sections on Tau Cell Biology
  • Written by experts in the field of cell biology
  • Includes cutting-edge materials

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1. Recombinant tau expression and purification

Stuart Feinstein

2. In vitro MT dynamics and MT ends

Nichole LaPointe

3. Methods related to investigating tau structure and MT bundling

Cyrus R. Safinya

4. Neurite outgrowth and retraction

Brett Cook

5. Methods related to studying tau fragmentation

Adrianna Ferrerira

6. Isoform-specific differences in tau in vitro aggregation

Truman C. Gamblin

7. Cosedimentation assays of microtubule binding

Holly Goodson

8. Methods to study tau aggregation

Songi Han

9. Methods to study tau phosphorylation

Diane Hanger

10. Structure of tau oligomers

Nicholas M. Kanaan

11. Use of mouse models for studies of pathological tau action

Virginia Lee and Sneha Narasimhan

12. Application of FRET and FCS to study tau structure-function

Elizabeth Rhoades

13. Use of the fly system to study tau action

Michelle Steinhilb

14. Single molecule assays with motor proteins

Christopher Berger

15. Tau clearance mechanisms in primary neurons with a focus on autophagy

Gail Johnson

16. Structural studies of tau

Eckhard Mandelkow

17. TIRF assays of tau effects on MT and actin cytoskeletons in vitro

Isabelle Arnal

18. TIRF assays of tau interactions with EB1

Isabelle Arnal

19. A novel approach to address tau biology, pathology, and propagation in vivo in mice using Adeno associated viruses

Susanne Wegmann
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