Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Pipeline Review, H1 2017 - Product Image

Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Pipeline Review, H1 2017

  • ID: 4311874
  • Report
  • 39 pages
  • Global Markets Direct
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FEATURED COMPANIES

  • CJ HealthCare Corp
  • Gilead Sciences Inc
  • Kyowa Hakko Kirin Co Ltd
  • MORE
Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Pipeline Review, H1 2017

Summary:

According to the recently published report 'Mitogen Activated Protein Kinase Kinase Kinase 5 - Pipeline Review, H1 2017'; Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) pipeline Target constitutes close to 10 molecules. Out of which approximately 8 molecules are developed by companies and remaining by the universities/institutes.

Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is a member of MAP kinase kinase kinase family encoded by MAP3K5 gene. It plays an important role in the cascades of cellular responses evoked by changes in the environment. It mediates signaling for determination of cell fate such as differentiation and survival. It plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. It is essential for host defense against a wide range of pathogens. It mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals.

The report 'Mitogen Activated Protein Kinase Kinase Kinase 5 - Pipeline Review, H1 2017' outlays comprehensive information on the Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.

It also reviews key players involved in Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Phase III, Preclinical and Discovery stages are 1, 5 and 2 respectively. Similarly, the universities portfolio in Preclinical and Discovery stages comprises 1 and 1 molecules, respectively. Report covers products from therapy areas Cardiovascular, Central Nervous System, Gastrointestinal, Immunology, Metabolic Disorders, Oncology and Undisclosed which include indications Neurodegenerative Diseases, Non-Alcoholic Steatohepatitis (NASH), Alcoholic Hepatitis, Amyotrophic Lateral Sclerosis, Cardiovascular Disease, Chronic Pain, Cirrhosis, Diabetic Nephropathy, Gastric Cancer, Hepatic Injury, Liver Diseases, Myocardial Infarction, Non Alcoholic Fatty Liver Disease (NAFLD), Pulmonary Hypertension, Rheumatoid Arthritis, Thrombosis and Unspecified.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope:
  • The report provides a snapshot of the global therapeutic landscape for Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25)
  • The report reviews Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) targeted therapeutics and enlists all their major and minor projects
  • The report assesses Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews latest news and deals related to Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) targeted therapeutics
Reasons to Buy:
  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
READ MORE
Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • CJ HealthCare Corp
  • Gilead Sciences Inc
  • Kyowa Hakko Kirin Co Ltd
  • MORE
  1. Introduction
  2. Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Overview
  3. Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Therapeutics Development
  4. Products under Development by Stage of Development
  5. Products under Development by Therapy Area
  6. Products under Development by Indication
  7. Products under Development by Companies
  8. Products under Development by Universities/Institutes
  9. Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Therapeutics Assessment
  10. Assessment by Mechanism of Action
  11. Assessment by Route of Administration
  12. Assessment by Molecule Type
  13. Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Companies Involved in Therapeutics Development
  14. Chipscreen Biosciences Ltd
  15. CJ HealthCare Corp
  16. Gilead Sciences Inc
  17. Kyowa Hakko Kirin Co Ltd
  18. Takeda Pharmaceutical Company Ltd
  19. Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Drug Profiles
  20. CS-410 - Drug Profile
  21. Product Description
  22. Mechanism Of Action
  23. R&D Progress
  24. GS-444217 - Drug Profile
  25. Product Description
  26. Mechanism Of Action
  27. R&D Progress
  28. GS-459679 - Drug Profile
  29. Product Description
  30. Mechanism Of Action
  31. R&D Progress
  32. selonsertib - Drug Profile
  33. Product Description
  34. Mechanism Of Action
  35. R&D Progress
  36. Small Molecule to Inhibit ASK-1 for Chronic Pain - Drug Profile
  37. Product Description
  38. Mechanism Of Action
  39. R&D Progress
  40. Small Molecule to Inhibit ASK1 for Liver Disease - Drug Profile
  41. Product Description
  42. Mechanism Of Action
  43. R&D Progress
  44. Small Molecule to Inhibit ASK1 for Thrombosis - Drug Profile
  45. Product Description
  46. Mechanism Of Action
  47. R&D Progress
  48. Small Molecules to Inhibit Apoptosis Signal-Regulating Kinase 1 - Drug Profile
  49. Product Description
  50. Mechanism Of Action
  51. R&D Progress
  52. Small Molecules to Inhibit ASK1 for Amyotropic Lateral Sclerosis - Drug Profile
  53. Product Description
  54. Mechanism Of Action
  55. R&D Progress
  56. Small Molecules to Inhibit ASK1 for Rheumatoid Arthritis, Myocardial Infarctions and Neurodegenerative Diseases - Drug Profile
  57. Product Description
  58. Mechanism Of Action
  59. R&D Progress
  60. Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Dormant Products
  61. Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Discontinued Products
  62. Mitogen Activated Protein Kinase Kinase Kinase 5 (Apoptosis Signal Regulating Kinase 1 or MAPK/ERK Kinase Kinase 5 or MAP3K5 or EC 2.7.11.25) - Product Development Milestones
  63. Featured News & Press Releases
  64. Apr 20, 2017: Gilead to Present Additional Clinical Data on Selonsertib at The International Liver Congress
  65. Nov 14, 2016: Phase 2 Data for Selonsertib in Nonalcoholic Steatohepatitis Presented at The Liver Meeting
  66. Oct 20, 2016: Gilead Announces Top-Line Phase 2 Results for GS-4997 (Selonsertib) in Nonalcoholic Steatohepatitis, Pulmonary Arterial Hypertension and Diabetic Kidney Disease
  67. Apr 16, 2016: Gilead Presents New Data on GS-4997 at The International Liver Congress
  68. Appendix
  69. Methodology
  70. Coverage
  71. Secondary Research
  72. Primary Research
  73. Expert Panel Validation
  74. Contact Us
  75. Disclaimer
List of Tables:
  1. Number of Products under Development by Stage of Development, H1
  2. Number of Products under Development by Therapy Areas, H1
  3. Number of Products under Development by Indication, H1
  4. Number of Products under Development by Companies, H1
  5. Products under Development by Companies, H1
  6. Number of Products under Investigation by Universities/Institutes, H1
  7. Products under Investigation by Universities/Institutes, H1
  8. Number of Products by Stage and Mechanism of Actions, H1
  9. Number of Products by Stage and Route of Administration, H1
  10. Number of Products by Stage and Molecule Type, H1
  11. Pipeline by Chipscreen Biosciences Ltd, H1
  12. Pipeline by CJ HealthCare Corp, H1
  13. Pipeline by Gilead Sciences Inc, H1
  14. Pipeline by Kyowa Hakko Kirin Co Ltd, H1
  15. Pipeline by Takeda Pharmaceutical Company Ltd, H1
  16. Dormant Projects, H1
  17. Discontinued Products, H1
List of Figures:
  1. Number of Products under Development by Stage of Development, H1
  2. Number of Products under Development by Therapy Areas, H1
  3. Number of Products under Development by Top 10 Indications, H1
  4. Number of Products by Stage and Mechanism of Actions, H1
  5. Number of Products by Stage and Route of Administration, H1
  6. Number of Products by Stage and Molecule Type, H1
Note: Product cover images may vary from those shown
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  • Chipscreen Biosciences Ltd
  • CJ HealthCare Corp
  • Gilead Sciences Inc
  • Kyowa Hakko Kirin Co Ltd
  • Takeda Pharmaceutical Company Ltd
Note: Product cover images may vary from those shown
5 of 5
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