Chemical Glycobiology, Vol 597. Methods in Enzymology

  • ID: 4318050
  • Book
  • 430 Pages
  • Elsevier Science and Technology
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Chemical Glycobiology, Volume 597, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume, the first on chemical glycobiology, contains comprehensive chapters on the Discovery of New Glycosidases from Metagenomic Libraries, Structure-guided directed evolution of glycosidases: A case study in engineering a blood group antigen-cleaving enzyme, A Pipeline for Studying and Engineering Single-Subunit Oligosaccharyltransferases, Directed evolution of glycopeptides using mRNA display, Chemoenzymatic Synthesis and Applications of Prokaryote-Specific UDP-Sugars, and Biosynthesis of Legionaminic Acid and its Incorporation into Glycoconjugates.

Readers will find the latest information on this developing area of research, as reported by leaders in the field.

  • Presents an updated volume in this regular series
  • Covers research on chemical glycobiology
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  1. Discovery of New Glycosidases from Metagenomic Libraries
    Stephen George Withers, Zach Armstrong and Peter Rahfeld
  2. Structure-guided directed evolution of glycosidases: A case study in engineering a blood group antigen-cleaving enzyme
    David Kwan
  3. A Pipeline for Studying and Engineering Single-Subunit Oligosaccharyltransferases
    Matt DeLisa
  4. Directed evolution of glycopeptides using mRNA display
    Isaac Krauss
  5. Chemoenzymatic Synthesis and Applications of Prokaryote-Specific UDP-Sugars
    Barbara Imperiali and Cristina Zamora
  6. Biosynthesis of Legionaminic Acid and its Incorporation into Glycoconjugates
    Michel Gilbert, Ian Schoenhofen and Martin Young
  7. Syntheses of fluorescent gangliosides for the studies of raft domains
    Makoto Kiso
  8. Profiling of Sugar Nucleotides
    Rob Field
  9. Chemoenzymatic glycan remodeling of natural and recombinant glycoproteins
    Lai-Xi Wang
  10. Glycoengineered Outer Membrane Vesicles as a platform for vaccine development
    Mario Feldman
  11. Identification and Design of Synthetic B Cell Epitopes for Carbohydrate-based Vaccines
    Peter Seeberger and Felix Broecker
  12. Strategies in the Design and Use of Synthetic 'Internal Glycan' Vaccines
    Ben Davis
  13. Evaluation of Virus Like Particle Based Tumor-Associated Carbohydrate Immunogen in a Mouse Tumor Model
    Xuefei Huang, Xuanjun Wu and Suttipun Sungsuwan
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