This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. J. Chris Gallagher and Daniel Bikle, is devoted to Vitamin D. Articles in this issue include: The Molecular and Cellular Mechanisms of Action of Vitamin D, Worldwide Review of Serum 25OHD Status; RDA Update (7 Years Post IOM); The Use of Vitamin D Metabolites and Analogs in the Treatment of Chronic Kidney Disease; Effect of Vitamin D on Falls and Physical Performance; Vitamin D Effect on BMD and Fractures; Bariatric Surgery and Vitamin D Metabolism, Role of Vitamin D in the Prevention and Treatment of Cancer; Role of Vitamin D in Cardiovascular Disease; Regulation of Immune Function by Vitamin D and its Use in Diseases of Immunity; Genetic Diseases of Vitamin D Metabolizing Enzymes; Measurement of Vitamin D Metabolites: Clinical Issues; The Free 25OHD Hypothesis, and Ethnic/Racial Differences in Vitamin D Levels: Physiologic or Pathologic.
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Foreword: Vitamin D Hormone: Where Do We Stand, Where Are We Heading?
Preface: Vitamin D: Mechanisms of Action and Clinical Applications
Biology and Mechanisms of Action of the Vitamin D Hormone
Global Overview of Vitamin D Status
Dietary Vitamin D Intake for the Elderly Population: Update on the Recommended Dietary Allowance for Vitamin D
Toward Clarity in Clinical Vitamin D Status Assessment: 25(OH)D Assay Standardization
Current Controversies: Are Free Vitamin Metabolite Levels a More Accurate Assessment of Vitamin D Status than Total Levels?
Effect of Vitamin D on Falls and Physical Performance
Vitamin D Effect on Bone Mineral Density and Fractures
Vitamin D Metabolism in Bariatric Surgery
The Use of Vitamin D Metabolites and Analogues in the Treatment of Chronic Kidney Disease
Vitamin D Receptor Signaling and Cancer
Role of Vitamin D in Cardiovascular Diseases
Regulation of Immune Function by Vitamin D and Its Use in Diseases of Immunity
Genetic Diseases of Vitamin D Metabolizing Enzymes
Genetic and Racial Differences in the Vitamin D Endocrine System