Cerebrotendinous Xanthomatosis Forecast in 18 Major Markets 2017-2027 - Product Image

Cerebrotendinous Xanthomatosis Forecast in 18 Major Markets 2017-2027

  • ID: 4400041
  • Report
  • 54 pages
  • Black Swan Analysis
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Cerebrotendinous Xanthomatosis in 18 Major Markets

Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive lipid storage disease caused by mutations in the CYP27A1 gene encoding a cytochrome P450 oxidase, also known as sterol 27-hydroxylase. The lack of the functional enzyme results in a reduced production of chenodeoxycholic acid (CDCA) and cholic acid (CA), components of bile, as well as accumulation of cholestanol and cholesterol in different tissues, e.g., brain, tendons, lenses, bones and vessels. No genotype-phenotype correlations have been identified, and the phenotypic manifestation can vary even between identical twins.

This report provides the current prevalent population for CTX across 18 Major Markets (USA, Canada, France, Germany, Italy, Spain, UK, Japan, Russia, Brazil, Poland, Austria, The Netherlands, Turkey, India, China, Mexico, Argentina) split by gender and 5-year age cohort. Along with the current prevalence, the report also contains a disease overview of the risk factors, disease diagnosis and prognosis along with specific variations by geography and ethnicity.

Providing a value-added level of insight, several of the main symptoms and co-morbidities of CTX have been quantified and presented alongside the overall prevalence figures. These sub-populations within the main disease are also included at a country level across the 10-year forecast snapshot.

Main symptoms and co-morbidities for CTX include:
  • Chronic diarrhoea
  • Developmental cataracts
  • Tendon xanthomas
  • Seizures
  • Intellectual impairment
  • Osteoporosis
This report is built using data and information sourced from the proprietary patient segmentation database. To generate accurate patient population estimates, the database utilises a combination of several world class sources that deliver the most up to date information form patient registries, clinical trials and epidemiology studies. All of the sources used to generate the data and analysis have been identified in the report.

Reasons to Buy:
  • Able to quantify patient populations in global CTX market to target the development of future products, pricing strategies and launch plans
  • Gain further insight into the prevalence of the subdivided types of CTX and identify patient segments with high potential
  • Delivery of more accurate information for clinical trials in study sizing and realistic patient recruitment for various countries
  • Provide a level of understanding on the impact from specific co-morbid conditions on CTX prevalent population
  • Identify sub-populations within CTX which require treatment
  • Gain an understanding of the specific markets that have the largest number of CTX patients
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Introduction
Cause of the Disease
Risk Factors & Prevention
Diagnosis of the Disease
Variation by Geography/Ethnicity
Disease Prognosis & Clinical Course
Key Comorbid Conditions / Features Associated With the Disease
Methodology for Quantification of Patient Numbers
Top-Line Prevalence for Cerebrotendinous Xanthomatosis
Comorbid Conditions of Cerebrotendinous Xanthomatosis Patients
Abbreviations Used in the Report
Other Publications
Online Patient-Based Databases
Patient-Based Offering
Online Pricing Data & Platforms
References
Appendix

List of Tables and Figures
Table 1. the Varied Manifestations of Cerebrotendinous Xanthomatosis
Table 2. Prevalence of Cerebrotendinous Xanthomatosis, Total (000S)
Table 3. Prevalence of Cerebrotendinous Xanthomatosis, Males (000S)
Table 4. Prevalence of Cerebrotendinous Xanthomatosis, Females (000S)
Table 5. Ctx Patients With Cataracts, Total (000S)
Table 6. Ctx Patients With Intellectual Impairment, Total (000S)
Table 7. Ctx Patients With Seizures, Total (000S)
Table 8. Ctx Patients With Tendon Xanthomas, Total (000S)
Table 9. Ctx Patients With Osteoporosis, Total (000S)
Table 10. Ctx Patients With Diarrhoea, Total (000S)
Table 11. Abbreviations and Acronyms Used in the Report
Table 12. Usa Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 13. Usa Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 14. Canada Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 15. Canada Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 16. France Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 17. France Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 18. Germany Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 19. Germany Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 20. Italy Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 21. Italy Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 22. Spain Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 23. Spain Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 24. Uk Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 25. Uk Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 26. Japan Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 27. Japan Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 28. Russia Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 29. Russia Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 30. Brazil Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 31. Brazil Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 32. Poland Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 33. Poland Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 34. Austria Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 35. Austria Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 36. the Netherlands Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 37. the Netherlands Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 38. Turkey Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 39. Turkey Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 40. India Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 41. India Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 42. China Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 43. China Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 44. Mexico Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 45. Mexico Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
Table 46. Argentina Prevalence of Ctx by 5-Yr Age Cohort, Males (000S)
Table 47. Argentina Prevalence of Ctx by 5-Yr Age Cohort, Females (000S)
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