This issue of Hematology/Oncology Clinics, edited by Dr. Ali Taher, focuses on Thalassemia. Topics include, but are not limited to, Molecular basis and genetic modifiers; Evolving spectrum of epidemiology; Clinical classification; Ineffective erythropoiesis, anemia and iron overload; Hypercoagulability and vascular disease; Clinical complications and their management; Transfusion and iron chelation therapy; Hematopoietic Stem Cell Transplantation in Thalassemia; Gene therapy and genome editing; Emerging therapies; Quality of life; Advances in understanding pathophysiology and treatment of fertility, pregnancy, and prenatal diagnosis in Thalassemia; and MRI for iron overload.
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Thalassemia - Table of Contents
The Evolving Spectrum of the Epidemiology of Thalassemia
Molecular Basis and Genetic Modifiers of Thalassemia
Clinical Classification, Screening, and Diagnosis for Thalassemia
Ineffective Erythropoiesis: Anemia and Iron Overload
Clinical Complications and Their Management
Hypercoagulability and Vascular Disease
Interaction of Transfusion and Iron Chelation in Thalassemias
Iron Chelation Therapy as a Modality of Management
MRI for Iron Overload in Thalassemia
Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia
Hematopoietic Stem Cell Transplantation in Thalassemia
Gene Therapy and Genome Editing
Director - Fellowship and Residents Research Program, Faculty of Medicine
Associate Chair - Research, Department of Internal Medicine
Deputy Director - Naef K. Basile Cancer Institute
American University of Beirut Medical Center
Beirut - Lebanon
Professor of Hematology & Medical Oncology (Adj.)
Emory School of Medicine
Atlanta - USA.