Calcitonin Gene Related Peptide (CGRP) - Pipeline Review, H1 2018

  • ID: 4479938
  • Drug Pipelines
  • 62 pages
  • Global Markets Direct
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FEATURED COMPANIES

  • Eli Lilly and Co
  • Serometrix LLC
  • MORE
Calcitonin Gene Related Peptide (CGRP) - Pipeline Review, H1 2018

Summary:

According to the recently published report 'Calcitonin Gene Related Peptide (CGRP) - Pipeline Review, H1 2018'; Calcitonin Gene Related Peptide (CGRP) pipeline Target constitutes close to 7 molecules. Out of which approximately 7 molecules are developed by Companies.

Calcitonin Gene Related Peptide (CGRP) - Calcitonin gene related peptide (CGRP) is a member of the calcitonin family of peptides. It exists in two forms alpha-CGRP and beta-CGRP. CGRP is produced in both peripheral and central neurons. CGRP is derived mainly from the cell bodies of motor neurons when synthesized in the ventral horn of the spinal cord and contribute to the regeneration of nervous tissue after injury.

CGRP is derived from dorsal root ganglion when synthesized in the dorsal horn of the spinal cord and linked to the transmission of pain. CGRP also plays an important role in cardiovascular homeostasis and nociception.

The report 'Calcitonin Gene Related Peptide (CGRP) - Pipeline Review, H1 2018' outlays comprehensive information on the Calcitonin Gene Related Peptide (CGRP) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.

It also reviews key players involved in Calcitonin Gene Related Peptide (CGRP) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Pre-Registration, Phase III, Preclinical and Discovery stages are 2, 1, 2 and 2 respectively. Report covers products from therapy areas Central Nervous System which include indications Migraine, Cluster Headache Syndrome, Dental Pain, Inflammatory Pain, Osteoarthritis Pain and Pain.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope:
  • The report provides a snapshot of the global therapeutic landscape for Calcitonin Gene Related Peptide (CGRP)
  • The report reviews Calcitonin Gene Related Peptide (CGRP) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in Calcitonin Gene Related Peptide (CGRP) targeted therapeutics and enlists all their major and minor projects
  • The report assesses Calcitonin Gene Related Peptide (CGRP) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews latest news and deals related to Calcitonin Gene Related Peptide (CGRP) targeted therapeutics
Reasons for Purchase:
  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for Calcitonin Gene Related Peptide (CGRP)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding Calcitonin Gene Related Peptide (CGRP) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
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Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • Eli Lilly and Co
  • Serometrix LLC
  • MORE
Introduction

Report Coverage

Calcitonin Gene Related Peptide (CGRP) - Overview

Calcitonin Gene Related Peptide (CGRP) - Therapeutics Development

Products under Development by Stage of Development

Products under Development by Therapy Area

Products under Development by Indication

Products under Development by Companies

Calcitonin Gene Related Peptide (CGRP) - Therapeutics Assessment

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Calcitonin Gene Related Peptide (CGRP) - Companies Involved in Therapeutics Development

Alder Biopharmaceuticals Inc

Eli Lilly and Co

Serometrix LLC

Teva Pharmaceutical Industries Ltd

Calcitonin Gene Related Peptide (CGRP) - Drug Profiles

AFAP-3 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

eptinezumab - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

fremanezumab - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

galcanezumab - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

NOXL-41 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecules to Inhibit CGRP for Migraine and Osteoarthritis Pain - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecules to Inhibit CGRP for Pain - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Calcitonin Gene Related Peptide (CGRP) - Dormant Products

Calcitonin Gene Related Peptide (CGRP) - Discontinued Products

Calcitonin Gene Related Peptide (CGRP) - Product Development Milestones

Featured News & Press Releases

Feb 02, 2018 : European Medicines Agency (EMA) Accepts Fremanezumab Marketing Authorization Application

Jan 08, 2018 : Alder Announces Eptinezumab Significantly Reduces Migraine Risk Meets Primary and All Key Secondary Endpoints in Pivotal PROMISE 2 Phase 3 Trial for Chronic Migraine Prevention

Dec 18, 2017: FDA Accepts Biologics License Application for Fremanezumab with Priority Review for Prevention of Migraine and Grants Fast Track Designation for Cluster Headache Development Program

Dec 11, 2017: FDA Accepts Biologics License Application to Review Galcanezumab for the Prevention of Migraine in Adults

Nov 29, 2017: The New England Journal of Medicine Publishes Data from Pivotal Phase III Trial of Fremanezumab for the Preventive Treatment of Chronic Migraine

Oct 17, 2017: Teva Announces Submission of Biologics License Application for Fremanezumab to the U.S. FDA

Sep 09, 2017: Teva Showcases Data Demonstrating Potential of Fremanezumab to Address Significant Unmet Need in Patients with Chronic and Episodic Migraine

Sep 08, 2017: IHC 2017: Lilly's Galcanezumab Demonstrates Positive Long-Term Safety Results For Up To 12 Months In Patients With Migraine

Sep 07, 2017: Alder BioPharmaceuticals to Present Data from Eptinezumab Development Program at 18th Congress of the International Headache Society

Sep 06, 2017: Lilly To Present New Data For Galcanezumab At The 18th Congress Of The International Headache Society

Sep 05, 2017: Teva to Present Fremanezumab Data on Migraine Prevention at the 18th Congress of the International Headache Society

Jun 27, 2017: Alder BioPharmaceuticals Announces Positive Eptinezumab Phase 3 Results for Prevention of Frequent Episodic Migraine

Jun 10, 2017: Lilly's Galcanezumab Significantly Reduces Number Of Migraine Headache Days For Patients With Migraine: New Results Presented At AHS

Jun 08, 2017: Lilly To Present Late-Breaking Data For Galcanezumab At The American Headache Society Annual Scientific Meeting

Jun 07, 2017: Alder to Present Migraine Prevention Data for Eptinezumab at 59th Annual Scientific Meeting of the American Headache Society

Appendix

Methodology

Coverage

Secondary Research

Secondary Research

Expert Panel Validation

Contact Us

Disclaimer

List of Tables

Number of Products under Development by Stage of Development, H1 2018

Number of Products under Development by Therapy Areas, H1 2018

Number of Products under Development by Indication, H1 2018

Number of Products under Development by Companies, H1 2018

Products under Development by Companies, H1 2018

Number of Products by Stage and Mechanism of Actions, H1 2018

Number of Products by Stage and Route of Administration, H1 2018

Number of Products by Stage and Molecule Type, H1 2018

Pipeline by Alder Biopharmaceuticals Inc, H1 2018

Pipeline by Eli Lilly and Co, H1 2018

Pipeline by Serometrix LLC, H1 2018

Pipeline by Teva Pharmaceutical Industries Ltd, H1 2018

Dormant Projects, H1 2018

Discontinued Products, H1 2018

List of Figures

Number of Products under Development by Stage of Development, H1 2018

Number of Products under Development by Indications, H1 2018

Number of Products by Stage and Mechanism of Actions, H1 2018

Number of Products by Routes of Administration, H1 2018

Number of Products by Stage and Routes of Administration, H1 2018

Number of Products by Molecule Types, H1 2018

Number of Products by Stage and Molecule Types, H1 2018
Note: Product cover images may vary from those shown
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  • Alder Biopharmaceuticals Inc
  • Eli Lilly and Co
  • Serometrix LLC
  • Teva Pharmaceutical Industries Ltd
Note: Product cover images may vary from those shown
5 of 5
Note: Product cover images may vary from those shown
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