Global GABA Receptor Agonist Drug Market, Dosage, Price & Clinical Pipeline Outlook 2024

  • ID: 4481440
  • Report
  • Region: Global
  • 220 Pages
  • Kuick Research
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FEATURED COMPANIES

  • Advicenne
  • Biocodex
  • Eli Lilly & Company
  • H.LundBeck
  • Novartis
  • OVATION Pharmaceuticals
  • MORE

“Global GABA Receptor Agonist Drug Market, Dosage, Price & Clinical Pipeline Outlook 2024” Report Highlights:

  • Global GABA Drugs Market Analysis by Dosage & Price
  • Promising GABA Receptor Agonist Therapeutics
  • Trends and Market Dynamics of GABA Receptor Agonist
  • Global GABA Receptor Agonists Clinical Pipeline =  49 Drugs
  • Marketed Global GABA Receptor Agonists Clinical Insight = 28 Drugs
  • GABA Receptor Agonist Market Analysis by Indication

The brain is indeed the vital organ of the body designated as the coordinating center of sensations, intellectual and nervous activities through various chemicals and receptors. Thus any dysregulation in the levels of chemicals or receptors can result in development of Central Nervous System Disorders. One of such component is Gamma-Aminobutyric Acid (GABA) which is an inhibitory neurotransmitter present in the brain has been found to be dominantly involved in developing central nervous system disorders.

Dysregulation of GABA can result in neurodegenerative disorders like Alzheimer's disease and Parkinson’s Disease; Psychiatric Disorders like Epilepsy, Depression, Anxiety, Sleep Disorders, ADHD, Alcoholism etc. All these diseases have been found to be developed by inappropriate levels and functioning of GABA. Lack of studies related to these conditions has resulted in highly unmet medical needs of this group of population.

Recent innovations in science and technology have aided better management of complicated diseases with better understanding of affected target of the brain and thus developing highly effective therapies which specifically treat the neurological and psychological diseases from their root cause rather than decreasing the symptoms of the disease. Increasing demand of therapies for these conditions and research findings about GABA has led to the development of a new class of therapeutics called GABA receptors which have been found to be highly effective for a wide range of neurological and psychological disorders.

Continuous increase in all of the above mentioned indications also leads to a significant decrease in the productivity affecting the global economy. This scenario alarmed the academia, healthcare and pharmaceutical industry to shift their focus towards this group of disorders. Cumulative efforts of these industries have led to the development and commercialization of more than 20 therapeutics in the market; collecting high revenues owing to increasing awareness and concern regarding neurological disorders.

Increasing ageing population and growing incidences of neurodegenerative disorders like Alzheimer’s disease and Parkinson’s disease in older population will drive the market for GABA receptors in the coming future. Moreover, increase in the prevalence of risk factors (such as diabetes), and lifestyle changes (such as alcohol consumption) also increase the chances of developing a mental disorder in adult and older group of population. Moreover psychological disorders like ADHD, anxiety and depression are occurring at an increasing rate in younger population which will again drive the global market for GABA receptors due to increasing needs to manage these disorders. Additionally, lack of effective treatment options in the market indicates a progressive growth and consumer acceptance for global GABA receptor Market.

However, low awareness regarding treatment of mental disorders, in developing nations like India; Russia; Brazil etc. is still a major challenge for the market growth. However, increased surveys, studies and awareness programs will surely aid in coping up with current challenges of GABA receptor market growth in these regions. Therefore, developing regions show highly opportunistic market for GABA receptors due to high prevalence of the disorders in these regions.

Increased funding by government and private organizations across emerging economies for treatment of neurological disorders is expected to provide growth opportunities for the market growth. Global GABA receptor market is growing at an impressive 6 CAGR with growing sales of major drugs in the market such as Baclofen and Propofol. Sales of Propofol is expected to reach US$ 6 Billion and Baclofen will collect more than US$ 400 Million for the developer pharmaceutical company in 2024. Additionally, exponential increase in the incidences of neurodegenerative, psychiatric and psychological disorders is going to fuel Global GABA receptor market in the coming future.

The Global Market for GABA receptors was analysed by studying the target patient base in major regions of the world, increasing awareness about the indications and current and future sales of various GABA receptors. Additionally, the report includes price and dosage analysis, treatment costs of the GABA receptors market products. Our research suggests that GABA Receptors have a highly progressive market with several promising products in the pipeline and increasing acceptance by consumers and end users.

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FEATURED COMPANIES

  • Advicenne
  • Biocodex
  • Eli Lilly & Company
  • H.LundBeck
  • Novartis
  • OVATION Pharmaceuticals
  • MORE

1. Prologue to (Gamma Amino Butyric Acid) GABA
1.1 Gamma - Amino Butyric Acid (GABA) – Chief Inhibitory Neurotransmitter of the Central Nervous System
1.2 GABA Receptors & Their Importance
1.3 GABA Receptor - Role & it’s Working Mechanism

2. Major Classes of GABA Receptor Therapeutics
2.1 GABA Receptor Agonist (Activators)
2.2 GABA Receptor Antagonist (Inhibitors)

3. GABA Receptor Market Segmentation by Type
3.1 GABAA
3.2 GABAB

4. Global GABA Drugs Market Analysis by Dosage & Price
4.1 Gabapentin (Gralise, Neurontin, Gabarone, Fanatrex)
4.1.1 Horizant (Gabapentin Enacarbil)
4.1.2 Regnite (Gabapentin Enacarbil,Japan)
4.1.3 Solzira (Gabapentin Enacbril)
4.1.4 Gralise (Gabapentin Enacbril)
4.2 Zolpidem
4.2.1 Ambien & Ambien CR ( Zolpidem Tartrate)
4.2.2 Edluar
4.2.3 Intermezzo
4.2.1 Zolpimist
4.3 Other Marketed GABA Receptor Therapeutics – Dosage & Price Analysis
4.3.1 Diastat AcuDial (Diazepam)
4.3.2 Campral EC (Acamprosate)
4.3.3 Stiripentol (Diacomit)
4.3.4 Gamibetal (GABOB)
4.3.5 Loreclezole
4.3.6 Lunesta(Eszopiclone)
4.3.7 Piacmilon
4.3.8 Onfi(Clobazam)
4.3.9 Gabrene (Progabide)
4.3.10 Diprivan (Propofol)
4.3.11 Regtect
4.3.12 Sonata Oral (Zaleplon, Starnoc, Andate)
4.3.13 Topamax Migraine

5. Promising GABA Receptor Agonist Therapeutics
5.1 Bamaluzole
5.2 Phenibut
5.3 Baclofen
5.4 Gaboxadol
5.5 Klonopin (clonazepam)
5.6 Tiagbine
5.7 GABA as Food Supplement

6. Global - Trends and Market Dynamics of GABA Receptor Agonist
6.1 Entry of Promising Therapeutics into the GABA Market Segment
6.2 Increasing Opportunities in Psychological Disorders Market

7. GABA Receptor Agonist Market Analysis by Indication
7.1 Attention Deficit Hyperactivity Disorder (ADHD)
7.2 Psychiatric Disorders & Depression
7.3 Alzheimer
7.4 Epilepsy & Seizure
7.5 Anxiety & Sleep Disorders
7.6 Obesity & Alcoholism

8. GABA Receptor Market Analysis by Region
8.1 US
8.2 Europe
8.3 Asia Pacific
8.4 Rest of the World

9. GABA Receptor Agonist Market Driving Parameters
9.1 Increasing Prevalence of GABA Related Disorders
9.2 Increase in Research & Development
9.3 Presence of Robust Clinical Pipeline

10. GABA Receptor Agonist Market Challenges
10.1 Scientific & Technical Limitations
10.2 Limited Research in GABA Therapeutics Segment & Cost Factor
10.3 Lack of Awareness & Low Market Penetration of GABA Receptor Agonist
10.4 Unregulated Market & Stringent FDA Regulations

11. Global GABA Receptor Agonist Market Future Forecast

12. Global GABA Receptor Agonists Clinical Pipeline by Company, Indication & Phase
12.1 Global GABA Receptor Agonists Pipeline Overview
12.2 Unknown
12.3 Research
12.4 Preclinical
12.5 Clinical
12.6 Phase-I
12.7 Phase-II
12.8 Phase-III
12.9 Preregistration

13. Marketed GABA Receptor Agonists Clinical Insight by Company & Indication

14. Competitive Analysis
14.1 Advicenne
14.2 AstraZeneca
14.3 Athena Drug Delivery Solutions
14.4 Biocodex
14.5 Elan Corporation
14.6 Eli Lilly & Company
14.7 H.LundBeck
14.8 GlaxoSmithKline
14.9 NovaDel Pharma
14.10 Novartis
14.11 OVATION Pharmaceuticals
14.12 Osmotica Pharmaceutical
14.13 Pfizer
14.14 sanofi-aventis
14.15 VIVUS
14.16 XenoPort

List of Figures:
Figure 1-1: GABA - Most Abundant Neurotransmitter
Figure 1-2: Features of GABA Receptors
Figure 1-3: GABA Receptor Activation & Function
Figure 2-1: Potential Therapeutic Role of GABA
Figure 3-1: Structure of GABAA
Figure 4-1: Gabapentin (Neurontin) - Dosage Analysis (mg)
Figure 4-2: Gabapentin (Neurontin) - Price Analysis (US$), 2018
Figure 4-3: Horizant - Dosage Analysis by Indication (mg/day)
Figure 4-4: Horizant- Price Analysis for 300mg & 600mg Pack(US$), 2018
Figure 4-5: Regnite - Price Analysis by Region (US$), 2018
Figure 4-6: Ambien - Maximum Permissible Dosage by Gender (mg)
Figure 4-7: Price Analysis -Ambien CR Oral Tablet (US$/30 Tablet Pack), 2018
Figure 4-8: Intermezzo - Dosage Analysis (mg)
Figure 4-9: Zolpidem - Price Analysis by Product, 2018
Figure 4-10: Diazepam Rectal Gel - Dosage Analysis by Age (mg/kg)
Figure 4-11: Diazepalm - Price Analysis by Product, 2018
Figure 4-12: Dosage Analysis - Acamprosate Tablets per day by Weight
Figure 4-13: GABOB- Maximum Recommended Dosage in Children by Condition (mg/Day)
Figure 4-14: GABOB - Maximum Recommended Dosage in Adults by Condition (mg/Day)
Figure 4-15: Propofol- Price Analysis (US$/ml), 2018
Figure 4-16: Global - Propofol Sales Analysis (US$ Million), 2013
Figure 4-17: Sonata Oral - Price Analysis (US$), 2018
Figure 4-18: Topomax - Monotherapy Dosage Analysis for patients >10 years (mg)
Figure 4-19: Topamax - Monotherapy Dosage (mg) Analysis for Patients < 10 years by Weight (kg)
Figure 4-20: Topamax - Price Analysis for 15 Tablet pack (mg), 2018
Figure 5-1: Global - Propofol Sales Forecast (US$ Billion), 2015-2024
Figure 5-2: Baclofen - Price Analysis (US$/mg), 2018
Figure 5-3: Baclofen - Intrathecal Solution Price Analysis (US$/ml), 2018
Figure 5-4: Global - Baclofen Sales Estimates (US$ Million), 2015 -2024
Figure 5-5: Tiagbine - Dosage Analysis by Indication (mg)
Figure 7-1: GABA Market Segmentation by Indication
Figure 7-2: Global - ADHD Prevalence by Region (%), 2016
Figure 7-3: Global - Prevalence of GABA Related Disorders (%), 2017
Figure 7-4: Global - Alzheimer Prevalence Forecast (Million) 2016-2050
Figure 7-5: Global- Number of Patients Diagnosed by Epilepsy (Million), 2016
Figure 7-6: Sleep Disorders Prevalence by Region (%), 2016
Figure 7-7: Global - Estimated Annual Cost of Sleep Disorder (US$ Million), 2016
Figure 8-1: US- ADHD Prevalence by Age (%), 2018
Figure 8-2: US-ADHD Prevalence by Gender (%), 2018
Figure 8-3: US- ADHD Prevalence by Race (%), 2018
Figure 8-4: US –People Diagnosed with GABA Related Disorders (Million), 2012-2016
Figure 8-5: Europe - Alzheimer’s Prevalence by Age (%), 2014-2016
Figure 8-6: Asia - Prevalence of ADHD among Children by Region (%), 2012-2016
Figure 8-7: Asia Pacific – GABA Related Sleep Disorder Prevalence (%), 2015-2016
Figure 9-1: Driving Factors of GABA Agonist Market
Figure 9-2: Current Psychiatric Drug Pipeline, 2018
Figure 10-1: GABA Receptor Agonist Market Challenges
Figure 12-1: Global - GABA Receptor Agonists Clinical Pipeline (%), 2018 till 2024
Figure 12-2: Global - GABA Receptor Agonists Clinical Pipeline (Number), 2018 till 2024
Figure 12-3: Global - GABA Receptor Agonists Clinical Pipeline (%),2018 till 2024
Figure 12-4: Global - GABA Receptor Agonists Clinical Pipeline (Number), 2018 till 2024

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  • Advicenne
  • AstraZeneca
  • Athena Drug Delivery Solutions
  • Biocodex
  • Elan Corporation
  • Eli Lilly & Company
  • GlaxoSmithKline
  • H.LundBeck
  • NovaDel Pharma
  • Novartis
  • OVATION Pharmaceuticals
  • Osmotica Pharmaceutical
  • Pfizer
  • VIVUS
  • XenoPort
  • sanofi-aventis
Note: Product cover images may vary from those shown
5 of 5
Note: Product cover images may vary from those shown
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