Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Pipeline Review, H1 2018

  • ID: 4521345
  • Drug Pipelines
  • 71 pages
  • Global Markets Direct
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FEATURED COMPANIES

  • ARMO Biosciences Inc
  • Bristol-Myers Squibb Co
  • F-star Biotechnology Ltd
  • GlaxoSmithKline Plc
  • Incyte Corp
  • Merck & Co Inc
  • MORE
Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Pipeline Review, H1 2018

Summary:

Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Lymphocyte-activation gene 3 or LAG-3 is a protein encoded by the LAG3 gene. It is involved in the maturation and activation of dendritic cells and lymphocyte activation. It binds to HLA class-II antigens.

Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) pipeline Target constitutes close to 24 molecules. The molecules developed by companies in Phase II, Phase I, Preclinical and Discovery stages are 3, 7, 10 and 4 respectively. Report covers products from therapy areas Oncology, Immunology and Cardiovascular which include indications Solid Tumor, Lymphoma, Non-Small Cell Lung Cancer, Advanced Malignancy, Autoimmune Disorders, Diffuse Large B-Cell Lymphoma, Hepatocellular Carcinoma, Melanoma, Bladder Cancer, Blood Cancer, Cardiovascular Disease, Cervical Cancer, Chronic Inflammation, Chronic Lymphocytic Leukemia (CLL), Colon Carcinoma, Colorectal Cancer, Esophageal Cancer, Follicular Lymphoma, Gastric Cancer, Gastroesophageal (GE) Junction Carcinomas, Gliosarcoma, Head And Neck Cancer Squamous Cell Carcinoma, Hodgkin Lymphoma (B-Cell Hodgkin Lymphoma), Kidney Cancer (Renal Cell Cancer), Metastatic Breast Cancer, Metastatic Cancer, Metastatic Melanoma, Multiple Myeloma (Kahler Disease), Non-Hodgkin Lymphoma, Ovarian Cancer, Plaque Psoriasis (Psoriasis Vulgaris), Recurrent Glioblastoma Multiforme (GBM) and Renal Cell Carcinoma.

The latest report Lymphocyte Activation Gene 3 Protein - Pipeline Review, H1 2018, outlays comprehensive information on the Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews key players involved in Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) targeted therapeutics development with respective active and dormant or discontinued projects.

The report is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope:
  • The report provides a snapshot of the global therapeutic landscape for Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3)
  • The report reviews Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) targeted therapeutics and enlists all their major and minor projects
  • The report assesses Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews latest news and deals related to Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) targeted therapeutics
Reasons for Purchase:
  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
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Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • ARMO Biosciences Inc
  • Bristol-Myers Squibb Co
  • F-star Biotechnology Ltd
  • GlaxoSmithKline Plc
  • Incyte Corp
  • Merck & Co Inc
  • MORE
Introduction

Report Coverage

Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Overview

Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Therapeutics Development

Products under Development by Stage of Development

Products under Development by Therapy Area

Products under Development by Indication

Products under Development by Companies

Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Therapeutics Assessment

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Companies Involved in Therapeutics Development

ARMO Biosciences Inc

Boehringer Ingelheim GmbH

Bristol-Myers Squibb Co

Crescendo Biologics Ltd

Enumeral Biomedical Holdings Inc

F-star Biotechnology Ltd

GigaGen Inc

GlaxoSmithKline Plc

Immutep Ltd

Incyte Corp

MacroGenics Inc

Merck & Co Inc

Novartis AG

Regeneron Pharmaceuticals Inc

Stcube Inc

Sutro Biopharma Inc

Symphogen A/S

Tesaro Inc

Xencor Inc

Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Drug Profiles

AM-0003 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

AVA-017 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

BI-754111 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Bispecific Monoclonal Antibody to Inhibit LAG3 for Oncology - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Bispecific Monoclonal Antibody to Target PD-1 and LAG-3 for Oncology - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

CB-213 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

cemiplimab + REGN-3767 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

ENUM-006 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

FS-118 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

IMP-731 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

IMP-761 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

INCAGN-2385 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

LAG-525 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

MGD-013 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

MK-4280 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Monoclonal Antibodies to Inhibit LAG3 for Oncology - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Recombinant Protein to Replace CD223 for Cardiovascular Disease and Chronic Inflammation - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

REGN-3767 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

relatlimab - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

STT-06 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Sym-022 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

TSR-033 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

TSR-075 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

XmAb-22841 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Dormant Products

Lymphocyte Activation Gene 3 Protein (Protein FDC or CD223 or LAG3) - Product Development Milestones

Featured News & Press Releases

Apr 11, 2018: Agenus Abstracts Accepted for Presentation at the American Association for Cancer Research (AACR) 2018 Annual Meeting

Apr 03, 2018: Immutep Provides Update On IMP

Mar 06, 2018: Immutep Announces United States Patent Grant for IMP701 Antibody

Nov 10, 2017: MacroGenics Announces Poster Presentations on MGD013 at 32nd Annual SITC Meeting 2

Sep 08, 2017: Prima Secures Japanese Patent Grant for IMP731 Antibody

Sep 05, 2017: MacroGenics Provides Update on its DART candidate MGD

Jul 16, 2017: Prima BioMed Announces Second Milestone Payment for IMP701 Program

Jun 04, 2017: Merck Strengthens Immuno-Oncology Portfolio through Expansion of F-star Collaboration including LAG-3/PD-L1 Bispecific Antibody

Jun 03, 2017: Anti-LAG-3 (BMS-986016) in Combination with Opdivo (nivolumab) Showed Activity in Patients with Melanoma Who Were Relapsed or Refractory to Anti-PD-1/PD-L1 Therapy

May 01, 2017: TESARO Announces Submission of Investigational New Drug Application for Anti-LAG Antibody TSR-033 to the U.S. FDA

Apr 05, 2017: F-star Presents Preclinical Data at AACR 2017 on Tumour Growth Inhibition in Colon Carcinoma Models using Bispecific Antibodies

Jan 03, 2017: Prima Announces New Product Candidate IMP761 - A LAG-3 Agonist Antibody

Sep 20, 2016: F-star to Present Encouraging Preclinical Data on Lead Bispecific Programme FS118 at Upcoming Conferences

Aug 25, 2016: European Patent Grants for IMP731 Antibody

Jun 07, 2016: F-star announces an agreement with CMC Biologics for manufacture of mAb2 bispecific antibodies

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

List of Tables

Number of Products under Development by Stage of Development, H1 2018

Number of Products under Development by Therapy Areas, H1 2018

Number of Products under Development by Indications, H1 2018

Number of Products under Development by Indications, H1 2018 (Contd..1), H1 2018

Number of Products under Development by Companies, H1 2018

Number of Products under Development by Companies, H1 2018 (Contd..1)

Products under Development by Companies, H1 2018

Products under Development by Companies, H1 2018 (Contd..1), H1 2018

Products under Development by Companies, H1 2018 (Contd..2), H1 2018

Products under Development by Companies, H1 2018 (Contd..3), H1 2018

Number of Products by Stage and Mechanism of Actions, H1 2018

Number of Products by Stage and Route of Administration, H1 2018

Number of Products by Stage and Molecule Type, H1 2018

Pipeline by ARMO Biosciences Inc, H1 2018

Pipeline by Boehringer Ingelheim GmbH, H1 2018

Pipeline by Bristol-Myers Squibb Co, H1 2018

Pipeline by Crescendo Biologics Ltd, H1 2018

Pipeline by Enumeral Biomedical Holdings Inc, H1 2018

Pipeline by F-star Biotechnology Ltd, H1 2018

Pipeline by GigaGen Inc, H1 2018

Pipeline by GlaxoSmithKline Plc, H1 2018

Pipeline by Immutep Ltd, H1 2018

Pipeline by Incyte Corp, H1 2018

Pipeline by MacroGenics Inc, H1 2018

Pipeline by Merck & Co Inc, H1 2018

Pipeline by Novartis AG, H1 2018

Pipeline by Regeneron Pharmaceuticals Inc, H1 2018

Pipeline by Stcube Inc, H1 2018

Pipeline by Sutro Biopharma Inc, H1 2018

Pipeline by Symphogen A/S, H1 2018

Pipeline by Tesaro Inc, H1 2018

Pipeline by Xencor Inc, H1 2018

Dormant Projects, H1 2018

List of Figures

Number of Products under Development by Stage of Development, H1 2018

Number of Products under Development by Therapy Areas, H1 2018

Number of Products under Development by Top 10 Indications, H1 2018

Number of Products by Mechanism of Actions, H1 2018

Number of Products by Stage and Mechanism of Actions, H1 2018

Number of Products by Stage and Route of Administration, H1 2018

Number of Products by Molecule Types, H1 2018

Number of Products by Stage and Molecule Types, H1
Note: Product cover images may vary from those shown
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  • ARMO Biosciences Inc
  • Boehringer Ingelheim GmbH
  • Bristol-Myers Squibb Co
  • Crescendo Biologics Ltd
  • Enumeral Biomedical Holdings Inc
  • F-star Biotechnology Ltd
  • GigaGen Inc
  • GlaxoSmithKline Plc
  • Immutep Ltd
  • Incyte Corp
  • MacroGenics Inc
  • Merck & Co Inc
  • Novartis AG
  • Regeneron Pharmaceuticals Inc
  • Stcube Inc
  • Sutro Biopharma Inc
  • Symphogen A/S
  • Tesaro Inc
  • Xencor Inc
Note: Product cover images may vary from those shown
5 of 5
Note: Product cover images may vary from those shown
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