Single-cell Omics: Emerging Technologies and Markets

  • ID: 4530570
  • Report
  • Region: Global
  • 186 Pages
  • BCC Research
15 % OFF
until Dec 31st 2018
1 of 6

FEATURED COMPANIES

  • Agilent Technologies Inc.
  • BGI Shenzhen
  • Celsee Diagnostics
  • Epic Sciences
  • Kellbenx Inc.
  • Rarecells Sas
  • MORE

Report Scope:

The scope of this report includes single cell analysis technologies, applications, industries, major funding initiatives, patents, and companies. The market sizes for single cell products are given for the years 2015, 2016, 2017 (estimated) and 2022 (forecasted).

This report reviews the single cell workflow steps and technologies and provides background on why single cell analysis is important. It then discusses some of the top research initiatives that are contributing to single cell applications. Market driving forces are also discussed.

The structure of several important industry subsectors is reviewed, as well as major industry acquisitions and strategic alliances from Jan. 2016 to Sept. 2017. Industry subsectors analyzed include target enrichment, droplet digital PCR, single cell DNA polymerase, DNA amplification, next-generation sequencing (NGS) instruments, single-cell proteomics, circulating tumor cell (CTC) capture and detection, liquid biopsy, preimplantation testing and immune sequencing.

The market for single cell analysis technologies is analyzed in depth. The market is analyzed by end user, application field, product type, omics method used, cell type, clinical indication and geography.

Specific geographic markets are discussed, including North America, Europe, Asia-Pacific and the rest of the world.

Market data covers the years 2015, 2016, 2017 (estimated) and 2022 (forecast).

More than 90 companies in the single cell analysis industry are profiled in this report.

This research provides a summary of the main industry acquisitions and strategic alliances from Jan. 2016 through Sept. 2017, including key alliance trends.

Report Includes:

  • 71 tables
  • An overview of the global markets and emerging technologies for single-cell genomics and proteomics
  • Analyses of global market trends, with data from 2016, estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022
  • Cell isolation technologies, including flow cytometry, laser capture microscopy, and micromanipulation
  • Sample preparation technologies, including microfluidics, whole genome amplification/pre-amplification
  • Analyses of next-generation sequencing, qPCR/PCR, microarrays, mass spectrometry, and microfluidics
  • End-use industry coverage, including research, drug discovery and development, diagnostics, and applied
  • Evaluation of the market's dynamics, including growth drivers, restraints, and opportunities
  • Profiles of major players in the industry including 1 Cellbio, 10x Genomics Inc., Angle PLC, Aviva Biosciences, Boreal Genomics, Dolomite Bio and Hifibio

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2 of 6

FEATURED COMPANIES

  • Agilent Technologies Inc.
  • BGI Shenzhen
  • Celsee Diagnostics
  • Epic Sciences
  • Kellbenx Inc.
  • Rarecells Sas
  • MORE

1 Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Methodology
  • Information Sources
  • Geographic Breakdown
  • Analyst's Credentials
  • Related Reports

2 Summary and Highlights

3 Overview

  • Introduction
  • Report Scope
  • Workflow
  • Technology Challenges
  • Markets
  • Growth Driving Forces
  • Key Trends
  • Industry

4 Technology Background

  • What Makes Single-cell Analysis Unique?
  • Single-cell Omics
  • Single-cell Analysis Workflow
  • Cell Isolation Technologies
  • Sample Preparation Technologies
  • Analysis Technologies
  • DNA Encoded Libraries in Single Cell Analysis
  • Genome-edited Single Cell Technologies
  • High-throughput Single-cell Technologies
  • Single-cell Multi-omics Technology
  • Single-cell RNA-Seq Technologies
  • Single-cell Technology Challenges

5 Single-cell Initiatives and Cores

  • 4D Nucleome Project
  • Allen Human Brain Atlases
  • Allen Institute of Cell Science
  • Brain Initiative
  • Centre of Single-cell Biology
  • Follow That Cell Challenge
  • Human Cell Atlas Initiative
  • Microbial Dark Matter Project
  • Next-Generation Single-cell Analysis Program
  • Single-cell Analysis Program
  • Single-cell Analysis Program-Transcriptome Project
  • Single-cell Proteomics and Lipidomics Project
  • Single-cell Surveyor Society
  • Cambridge Single-cell Analysis Core Facility
  • Harvard Medical School Single-cell Core
  • Mayo Medical Genome Facility
  • National Center for Single-cell Biology
  • Single-cell Analysis Core
  • UC San Francisco Single-cell Analysis Center

6 Single-cell Applications

  • Introduction
  • Basic Cell Biology
  • Immunology
  • Microbiology
  • Neurology
  • Oncology
  • Stem Cell Biology
  • Liquid Biopsy
  • Preimplantation Genetic Diagnosis and Screening
  • Human Identification
  • Agriculture

7 Single-cell Industry

  • Introduction
  • Target Enrichment Industry
  • Droplet Digital PCR Industry
  • Single-cell DNA Polymerase Industry
  • DNA Amplification Industry
  • NGS Instrument Industry
  • Single-cell Proteomics Industry
  • CTC Capture and Detection Industry
  • Liquid Biopsy Industry
  • Preimplantation Testing Industry
  • Immune Sequencing Industry

8 Acquisitions and Strategic Alliances

  • Acquisitions
  • Strategic Alliances

9 Single-cell Omics Markets

  • Growth Driving Forces
  • Single-cell Omics Market
  • Single-cell omics Diagnostics Markets
  • Breast Cancer
  • Colorectal Cancer
  • Ovarian Cancer
  • Lung Cancer
  • Multiple Myeloma
  • Prostate Cancer
  • Research Market
  • Drug Discovery and Development Market
  • Applied Market
  • Single-cell Omics Geographical Market

10 Patent Review

11 Company Profiles

  • 1 Cellbio
  • 10X Genomics Inc.
  • Accelerate Diagnostics Inc.
  • Agilent Technologies Inc.
  • Ambry Genetics
  • Angle Plc
  • Apocell Inc.
  • Asuragen Inc.
  • Atreca Inc.
  • Aviva Biosciences
  • Becton, Dickinson And Co.
  • Berry Genomics Co. Ltd.
  • BGI Shenzhen
  • Bioarray S.L.
  • Biocept Inc.
  • Biofluidica Inc.
  • Bio-Rad Laboratories Inc.
  • Bio-Techne Ltd.
  • Boreal Genomics
  • Cell Microsystems Inc.
  • Celsee Diagnostics
  • Cellular Research Inc.
  • Chronix Biomedical
  • Circulomics Inc.
  • Cooper Surgical Inc.
  • Cynvenio Biosystems Inc.
  • Cytena Gmbh
  • Cytolumina Technologies Corp. Inc.
  • Cytotrack Aps
  • Danaher Corp.
  • Diagnologix Llc
  • DNA Electronics Ltd.
  • Dolomite Bio
  • Engine Biosciences Pte. Ltd.
  • Epic Sciences
  • Exosome Diagnostics Inc.
  • Fetolumina Technologies Corp.
  • Flowjo Llc
  • Fluidigm Corp
  • Fluxion Biosciences Inc.
  • Ge Healthcare
  • Gigagen Inc.
  • Gilupi Gmbh
  • Good Start Genetics Inc.
  • Hifibio
  • HTG Molecular Diagnostics Inc.
  • Illumina Inc.
  • Incelldx Inc.
  • Isoplexis Corp.
  • Kellbenx Inc.
  • Laboratory Corp. Of America Inc.
  • LGC Biosearch Technologies
  • Menarini Silicon Biosystems
  • Merck Kgaa
  • Mission Bio Inc.
  • Muse Biotechnology Inc.
  • Namocell Inc.
  • Nanocellect Biomedical Inc.
  • Nanostring Technologies Inc.
  • Natera Inc.
  • New Oncology Gmbh
  • Nodality Inc.
  • Nugen Technologies Inc.
  • Oxford Nanopore Technologies Ltd.
  • Pacific Biosciences Of California Inc.
  • Perkinelmer Inc.
  • Qiagen NV
  • Rarecells Sas
  • Rarecyte Inc.
  • Ravata Solutions
  • Reproductive Health Science Pty Ltd.
  • Resolution Bioscience Inc.
  • Roche Holding AG
  • Royal Philips
  • Screencell
  • Sengenics International Pte Ltd.
  • Singulomics Corp.
  • Somagenics Inc.
  • Sphere Fluidics Ltd.
  • Stratec Biomedical Ag
  • Swift Biosciences Inc.
  • Sygnis AG
  • Sysmex Corp.
  • Takara Bio Inc.
  • Thermo Fisher Scientific Inc.
  • Thorne Diagnostics Inc.
  • Trovagene Inc.
  • Tumorgen Mdx Llc
  • Vitatex Inc.
  • Yikon Genomics Co. Ltd.

List of Tables
Summary Table: Single-cell Omics Market, by End User, Through 2022
Table 1: Key Single-cell Omics Market Segments Covered
Table 2: Single Cell Analysis Workflow
Table 3: Single-cell Omics Market, by Analyte Type, Through 2022
Table 4: Single Cell Analysis Market Growth Driving Forces
Table 5: Trends in Single-cell Analysis
Table 6: Key Segments within the Single-cell Analysis Industry
Table 7: Unique Technical Challenges of Single-cell Analysis
Table 8: Single-cell Omics
Table 9: Single-cell analysis Workflow
Table 10: Cell Differentiators
Table 11: Cell Isolation Technologies
Table 12: Single Cell Sample Preparation Workflows
Table 13: Molecular Analysis Technologies
Table 14: Genome-editing Technologies
Table 15: Comparison of Gene Editing Platforms
Table 16: High-throughput Single-cell Technologies
Table 17: Technical Strategies for Single-cell Multi-omics
Table 18: Emerging Droplet-based Single-cell RNA-seq Technologies
Table 19: Technical Challenges for Single-cell Analysis
Table 20: Key Single-cell Research and Development Projects
Table 21: Single-cell Core Research Facilities
Table 22: Single-cell Analysis: Near- to Mid-term Applications
Table 23: Key Objectives of Basic Single-cell Biology
Table 24: Single-cell Analysis to Identify Cancer Driver Mutations
Table 25: Stem Cells
Table 26: Biomarkers in Liquid Biopsy
Table 27: Factors in Tissue Biopsy
Table 28: Preimplantation Genetic Diagnosis and Screening Applications
Table 29: Key Segments Within the Single-cell omics Industry
Table 30: Target Enrichment Industry
Table 31: Advantages of Droplet Digital PCR for Single-cell analysis
Table 32: Droplet Digital PCR Industry
Table 33: Single-cell DNA Polymerase Industry
Table 34: Single-cell Sequencing Workflow
Table 35: Single-cell DNA Amplification Industry
Table 36: Next Generation Sequencing Instrument Company Summary
Table 37: Single-cell Proteomics Industry
Table 38: CTC Capture and Detection Industry
Table 39: Liquid Biopsy Industry Company Focus
Table 40: Example of NGS-based Liquid Biopsy Market Differentiation
Table 41: Preimplantation Diagnostics Platforms
Table 42: Preimplantation Genetic Testing Industry
Table 43: Immune System Profiling Industry
Table 44: Single-cell Industry Acquisitions, Jan. 2016 Through Sept. 2017
Table 45: Single-cell Industry Strategic Alliances, Jan. 2016 Through Sept. 2017
Table 46: Single-cell Omics Market Growth Driving Forces
Table 47: Single-cell Analysis Market, by End-use Industry, Through 2022
Table 48: Single-cell Omics Market, by Product Type, Through 2022
Table 49: Single-cell Omics Market, by Field, Through 2022
Table 50: Single-cell Omics Market, by Analysis Type, Through 2022
Table 51: Single-cell Omics Market, by Cell Type, Through 2022
Table 52: Single-cell Diagnostics Market, by Indication, Through 2022
Table 53: Single-cell Omics Diagnostics Market, by Analysis Type, Through 2022
Table 54: CTC Market Landscape
Table 55: Omics-based CTC Cancer Focus
Table 56: CTC Diagnostics Market, by Indication, Through 2022
Table 57: Five-year Survival Rate for Ovarian Cancer
Table 58: Single-cell Omics Research Market, by Field, Through 2022
Table 59: Single-cell Omics Research Market, by Analysis Type, Through 2022
Table 60: Single-cell Omics Research Market, by Cell Type, Through 2022
Table 61: Single-cell Omics Drug Discovery and Development Market, by Field, Through 2022
Table 62: Single-cell Omics Drug Discovery and Development Market, by Analysis Type, Through 2022
Table 63: Single-cell Omics Drug Discovery and Development Market, by Cell Type, Through 2022
Table 64: Single-cell Omics Applied Market, by Application, Through 2022
Table 65: Single-cell Omics Applied Market, by Analysis Type, Through 2022
Table 66: Single-cell Omics Applied Market, by Cell Type, Through 2022
Table 67: Single-cell Omics Market, by Region, Through 2022
Table 68: Patents on Single-cell Technologies, by Region, 2007 Through Oct. 2017
Table 69: Patents on CTC-related Technologies, by Region, 2007 Through Oct. 2017
Table 70: Patents on Microfluidics-related Single Cell Technologies, 2007 Through Oct. 2017
Table 71: Patents on High-Throughput-related Single Cell Technologies, 2007 Through Oct. 2017

List of Figures
Summary Figure: Single-cell Omics Market, by End User, 2015-2022

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FEATURED COMPANIES

  • Agilent Technologies Inc.
  • BGI Shenzhen
  • Celsee Diagnostics
  • Epic Sciences
  • Kellbenx Inc.
  • Rarecells Sas
  • MORE

Summary:

Single-cell omics analysis technologies are emerging as a disruptive force in the life science research, pharmaceutical and diagnostics industries. Single cell analysis is critical for analyzing complex, heterogeneous biological systems that occur at many levels of life sciences from stem cell biology to cancer to forensics.

In cancer, for example, a tumor may shed cells into the bloodstream that give clues about the aggressiveness of that tumor or how it is responding to a particular drug therapy. It is important to analyze these individual cells, called circulating tumor cells, to aid in monitoring the disease or to guide therapy strategies. The emerging field of liquid biopsy addresses this medical need.

Single-cell omics are also important to fundamental biological research, for example, to identify cancer mutation drivers or factors that influence stem cell potency. The trend toward biological drugs, stem cell therapies, and new cancer treatments is also beneficial to the single cell analysis markets due to its importance in these fields.

Report Scope:

The scope of this report includes single cell analysis technologies, applications, industries, major funding initiatives, patents, and companies. The market sizes for single cell products are given for the years 2015, 2016, 2017 (estimated) and 2022 (forecasted).

This report reviews the single cell workflow steps and technologies and provides background on why single cell analysis is important. It then discusses some of the top research initiatives that are contributing to single cell applications. Market driving forces are also discussed.

The structure of several important industry subsectors is reviewed, as well as major industry acquisitions and strategic alliances from Jan. 2016 to Sept. 2017. Industry subsectors analyzed include target enrichment, droplet digital PCR, single cell DNA polymerase, DNA amplification, next generation sequencing (NGS) instruments, single cell proteomics, circulating tumor cell (CTC) capture and detection, liquid biopsy, preimplantation testing and immune sequencing.

The market for single cell analysis technologies is analyzed in depth. The market is analyzed by end user, application field, product type, omics method used, cell type, clinical indication, and geography.

Specific geographic markets are discussed, including North America, Europe, Asia-Pacific and the rest of the world.

Market data covers the years 2015, 2016, 2017 (estimated) and 2022 (forecast).

More than 90 companies in the single cell analysis industry are profiled in this report.

This research provides a summary of the main industry acquisitions and strategic alliances from Jan. 2016 through Sept. 2017, including key alliance trends.

Reasons for Doing This Study:

The life science industry is moving towards digitization with the advent of newer technologies including advanced genetic sequencing and microfluidics systems. As many biological systems contain heterogeneous populations of cells, heretofore many analysis methods measured mixtures of different cell types.

Single cell analysis is a disruptive technology that enables analysis of single cells out of a complex mixture of cells. This type of analysis is key to understanding complex systems in fields as diverse as neurology, stem cell biology and cancer.

At the same time, advances in genome editing, high-throughput systems and microfluidics technologies have enabled the rapid, parallel analysis of smaller samples that are common with single cells. Based on this, single cell analysis markets are rapidly emerging and the need for industry and market characterization is great.

Also, the single cell field is growing beyond basic research into applied fields and molecular diagnostics applications.

The outstanding growth potential for single cell analysis products makes it particularly timely for doing this updated report.

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  • Accelerate Diagnostics Inc.
  • Agilent Technologies Inc.
  • Ambry Genetics
  • Angle Plc
  • Apocell Inc.
  • Asuragen Inc.
  • Atreca Inc.
  • Aviva Biosciences
  • BGI Shenzhen
  • Becton, Dickinson And Co.
  • Berry Genomics Co. Ltd.
  • Bio-Rad Laboratories Inc.
  • Bio-Techne Ltd.
  • Bioarray S.L.
  • Biocept Inc.
  • Biofluidica Inc.
  • Boreal Genomics
  • Cell Microsystems Inc.
  • Cellular Research Inc.
  • Celsee Diagnostics
  • Chronix Biomedical
  • Circulomics Inc.
  • Cooper Surgical Inc.
  • Cynvenio Biosystems Inc.
  • Cytotrack Aps
  • Danaher Corp.
  • Diagnologix Llc
  • DNA Electronics Ltd.
  • Epic Sciences
  • Exosome Diagnostics Inc.
  • Flowjo Llc
  • Fluidigm Corp
  • Fluxion Biosciences Inc.
  • GE Healthcare
  • Gigagen Inc.
  • Good Start Genetics Inc.
  • HTG Molecular Diagnostics Inc.
  • Illumina Inc.
  • Kellbenx Inc.
  • Laboratory Corp. Of America Inc.
  • Menarini Silicon Biosystems
  • Merck Kgaa
  • Namocell Inc.
  • Nanocellect Biomedical Inc.
  • Nanostring Technologies Inc.
  • Natera Inc.
  • New Oncology Gmbh
  • Nodality Inc.
  • Nugen Technologies Inc.
  • Oxford Nanopore Technologies Ltd.
  • Pacific Biosciences Of California Inc.
  • Perkinelmer Inc.
  • Qiagen Nv
  • Rarecells Sas
  • Rarecyte Inc.
  • Resolution Bioscience Inc.
  • Roche Holding AG
  • Royal Philips
  • Screencell
  • Sengenics International Pte Ltd.
  • Sphere Fluidics Ltd.
  • Stratec Biomedical AG
  • Sysmex Corp.
  • Takara Bio Inc.
  • Thermo Fisher Scientific Inc.
  • Thorne Diagnostics Inc.
  • Trovagene Inc.
  • Vitatex Inc.
  • Yikon Genomics Co. Ltd.
Note: Product cover images may vary from those shown
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