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Advair

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    Report

  • 37 Pages
  • July 2018
  • Region: Global
  • Citeline
  • ID: 4533481
Drug Overview
Advair ([fluticasone propionate + salmeterol]; GlaxoSmithKline) is a fixed-dose combination of an inhaled corticosteroid (fluticasone propionate) and a long-acting beta 2 agonist (salmeterol). The drug has anti-inflammatory and bronchodilatory effects on patients with asthma. It is administered twice daily through a dry powder inhaler device called Advair Diskus, or a pressurized metered-dose inhaler device known as Advair hydrofluoroalkane (HFA).

Twice-daily Advair was the first ICS/LABA combination to launch and quickly became the gold standard in its class and across the asthma and COPD markets. It was first launched for asthma in the UK in 1999 and was rolled out in the rest of Europe in 2000–01 and in the US in 2001. It became available in Japan in 2007. While the majority of sales are for asthma, the drug is a blockbuster for COPD as well.

Table of Contents

OVERVIEW
Drug Overview
Product Profiles
Advair: Chronic obstructive pulmonary disease (COPD)
Advair: Asthma
LIST OF FIGURES
Figure 1: Advair for COPD – SWOT analysis
Figure 2: The authors drug assessment summary of Advair for COPD
Figure 3: The authors drug assessment summary of Advair for COPD
Figure 4: Advair sales for COPD across the US, Japan, and five major EU markets, by country, 2017–26
Figure 5: Advair for asthma – SWOT analysis
Figure 6: The authors drug assessment summary of Advair in asthma
Figure 7: The authors drug assessment summary of Advair in asthma
Figure 8: Advair sales for asthma across the US, Japan, and five major EU markets, by country, 2017–26
LIST OF TABLES
Table 1: Advair drug profile
Table 2: Advair Phase III data in COPD
Table 3: Advair sales for COPD across the US, Japan, and five major EU markets, by country ($m), 2017–26
Table 4: Advair drug profile
Table 5: Advair Diskus pivotal trial data in asthma
Table 6: Advair HFA pivotal trial data in asthma
Table 7: Advair late-phase trial data in asthma
Table 8: Advair sales for asthma across the US, Japan, and five major EU markets, by country ($m), 2017–26