Inflammatory Skin Diseases Drug Development Pipeline Review, 2018

  • ID: 4557092
  • Report
  • Region: Global
  • 112 Pages
  • GBI Research
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FEATURED COMPANIES

  • 3SBio Inc
  • Cassiopea SpA
  • ELORAC Inc
  • LEO Pharma A/S
  • Novan Inc
  • Phagelux Inc
  • MORE

Acne vulgaris is a chronic skin disease involving blockage and inflammation of pilosebaceous follicles.Symptoms include crusting of skin bumps, cysts, papules (small red bumps), scarring of the skin and redness around the skin eruptions. There are 60 products in development for this indication, and companies operating in this space include Cassiopea and Elorac.

Rosacea is a chronic and potentially life-disruptive disorder primarily of the facial skin, often characterized by flare-ups and remissions. Symptoms include frequent redness of the face, or flushing, small, red lines under the skin, a swollen nose and thick skin, usually on the forehead, chin, and cheeks. There are 18 products in development for this indication, and companies operating in this space include Dermata Therapeutics and Promius Pharma.

Chronic urticaria, also known as hives, are an outbreak of swollen, pale red bumps, patches, or welts on the skin that appear suddenly either as a result of allergies, or for other reasons. The main symptom is itchy rashes. There are 17 products in development for this indication, and companies operating in this space include GlaxoSmithKline and Novartis.

Molecular targets acted on by products in development for inflammatory skin disorders include cytokines, ribosomal RNA and retinoic acid receptors.

This report "Inflammatory Skin Diseases Drug Development Pipeline Review, 2018"provides an overview of the pipeline landscape for inflammatory skin disorders and comprehensive information on the therapeutics under development and key players involved in therapeutic development for acne vulgaris, rosacea and chronic urticaria (also known as hives). It also features dormant and discontinued products.

Scope

  • Which companies are the most active within each pipeline?
  • Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
  • To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
  • What are the most important R&D milestones and data publications to have happened in this disease area?

Reasons to buy

  • Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
  • Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication and a comprehensive picture of recent updates and milestones for each
  • Analyze the companies, institutions and universities currently operating in the pipeline and the products being fielded by each of these
  • Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration.
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Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • 3SBio Inc
  • Cassiopea SpA
  • ELORAC Inc
  • LEO Pharma A/S
  • Novan Inc
  • Phagelux Inc
  • MORE

1 Table of Contents

2 Introduction
2.1 Inflammatory Skin Diseases Report Coverage
2.2 Acne Vulgaris - Overview
2.3 Rosacea - Overview
2.4 Chronic Urticaria Or Hives - Overview

3 Therapeutics Development
3.1 Acne Vulgaris
3.2 Rosacea
3.3 Chronic Urticaria Or Hives

4 Therapeutics Assessment
4.1 Acne Vulgaris
4.2 Rosacea
4.3 Chronic Urticaria Or Hives

5 Companies Involved in Therapeutics Development
5.1 Acne Vulgaris
5.2 Rosacea
5.3 Chronic Urticaria Or Hives

6 Dormant Projects
6.1 Acne Vulgaris
6.2 Rosacea
6.3 Chronic Urticaria Or Hives

7 Discontinued Products
7.1 Acne Vulgaris
7.2 Rosacea
7.3 Chronic Urticaria Or Hives

8 Product Development Milestones
8.1 Acne Vulgaris
8.2 Rosacea
8.3 Chronic Urticaria Or Hives

9 Appendix
9.1 Methodology
9.2 Coverage
9.3 Secondary Research
9.4 Primary Research
9.5 Expert Panel Validation

List of Tables
Table 1: Number of Products under Development for Acne Vulgaris
Table 2: Number of Products under Development by Companies, Acne Vulgaris
Table 3: Number of Products under Development by Universities/Institutes, Acne Vulgaris
Table 4: Products under Development by Companies, Acne Vulgaris
Table 5: Products under Development by Universities/Institutes, Acne Vulgaris
Table 6: Number of Products under Development for Rosacea
Table 7: Number of Products under Development by Companies, Rosacea
Table 8: Products under Development by Companies, Rosacea
Table 9: Number of Products under Development for Chronic Urticaria Or Hives
Table 10: Number of Products under Development by Companies, Chronic Urticaria Or Hives
Table 11: Products under Development by Companies, Chronic Urticaria Or Hives
Table 12: Number of Products by Stage and Target, Acne Vulgaris
Table 13: Number of Products by Stage and Mechanism of Action, Acne Vulgaris
Table 14: Number of Products by Stage and Route of Administration, Acne Vulgaris
Table 15: Number of Products by Stage and Molecule Type, Acne Vulgaris
Table 16: Number of Products by Stage and Target, Rosacea
Table 17: Number of Products by Stage and Mechanism of Action, Rosacea
Table 18: Number of Products by Stage and Route of Administration, Rosacea
Table 19: Number of Products by Stage and Molecule Type, Rosacea
Table 20: Number of Products by Stage and Target, Chronic Urticaria Or Hives
Table 21: Number of Products by Stage and Mechanism of Action, Chronic Urticaria Or Hives
Table 22: Number of Products by Stage and Route of Administration, Chronic Urticaria Or Hives
Table 23: Number of Products by Stage and Molecule Type, Chronic Urticaria Or Hives
Table 24: Acne Vulgaris - Pipeline by 3SBio Inc,
Table 25: Acne Vulgaris - Pipeline by BioPharmX Inc,
Table 26: Acne Vulgaris - Pipeline by Braintree Laboratories Inc,
Table 27: Acne Vulgaris - Pipeline by Cassiopea SpA,
Table 28: Acne Vulgaris - Pipeline by Cutanea Life Sciences Inc,
Table 29: Acne Vulgaris - Pipeline by Daewoong Co Ltd,
Table 30: Acne Vulgaris - Pipeline by Deltanoid Pharmaceuticals Inc,
Table 31: Acne Vulgaris - Pipeline by ELORAC Inc,
Table 32: Acne Vulgaris - Pipeline by Foamix Pharmaceuticals Ltd,
Table 33: Acne Vulgaris - Pipeline by Galderma SA,
Table 34: Acne Vulgaris - Pipeline by Helix BioMedix Inc,
Table 35: Acne Vulgaris - Pipeline by Innovation Pharmaceuticals Inc,
Table 36: Acne Vulgaris - Pipeline by Lee's Pharmaceutical Holdings Ltd,
Table 37: Acne Vulgaris - Pipeline by LEO Pharma A/S,
Table 38: Acne Vulgaris - Pipeline by Melinta Therapeutics Inc,
Table 39: Acne Vulgaris - Pipeline by Novabiotics Ltd,
Table 40: Acne Vulgaris - Pipeline by Novan Inc,
Table 41: Acne Vulgaris - Pipeline by Novartis AG,
Table 42: Acne Vulgaris - Pipeline by Paratek Pharmaceuticals Inc,
Table 43: Acne Vulgaris - Pipeline by Pfizer Inc,
Table 44: Acne Vulgaris - Pipeline by Phagelux Inc,
Table 45: Acne Vulgaris - Pipeline by Phosphagenics Ltd,
Table 46: Acne Vulgaris - Pipeline by Photocure ASA,
Table 47: Acne Vulgaris - Pipeline by Promius Pharma LLC,
Table 48: Acne Vulgaris - Pipeline by Provectus Biopharmaceuticals Inc,
Table 49:AcneVulgaris-PipelinebyRealmTherapeuticsPlc,
Table 50: Acne Vulgaris - Pipeline by Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd,
Table 51: Acne Vulgaris - Pipeline by Sol-Gel Technologies Ltd,
Table 52: Acne Vulgaris - Pipeline by Sun Pharmaceutical Industries Ltd,
Table 53: Acne Vulgaris - Pipeline by Valeant Pharmaceuticals International Inc,
Table 54: Acne Vulgaris - Pipeline by Vyome Biosciences Pvt Ltd,
Table 55: Acne Vulgaris - Pipeline by XBiotech Inc,
Table 56: Rosacea - Pipeline by Almirall SA,
Table 57: Rosacea - Pipeline by Amorepacific Corp,
Table 58: Rosacea - Pipeline by BioPharmX Inc,
Table 59: Rosacea - Pipeline by Cutanea Life Sciences Inc,
Table 60: Rosacea - Pipeline by ELORAC Inc,
Table 61: Rosacea - Pipeline by Foamix Pharmaceuticals Ltd,
Table 62: Rosacea - Pipeline by Hovione FarmaCiencia SA,
Table 63: Rosacea - Pipeline by Promius Pharma LLC,
Table 64: Rosacea - Pipeline by Sol-Gel Technologies Ltd,
Table 65: Chronic Urticaria Or Hives - Pipeline by ELORAC Inc,
Table 66: Chronic Urticaria Or Hives - Pipeline by F. Hoffmann-La Roche Ltd,
Table 67: Chronic Urticaria Or Hives - Pipeline by Faes Farma SA,
Table 68: Chronic Urticaria Or Hives - Pipeline by Fountain Biopharma Inc,
Table 69: Chronic Urticaria Or Hives - Pipeline by Genentech Inc,
Table 70: Chronic Urticaria Or Hives - Pipeline by GlaxoSmithKline Plc,
Table 71: Chronic Urticaria Or Hives - Pipeline by Glenmark Pharmaceuticals Ltd,
Table 72: Chronic Urticaria Or Hives - Pipeline by Mycenax Biotech Inc,
Table 73: Chronic Urticaria Or Hives - Pipeline by Novartis AG,
Table 74: Chronic Urticaria Or Hives - Pipeline by Synermore Biologics Co Ltd,
Table 75: Acne Vulgaris - Dormant Projects,
Table 76: Rosacea - Dormant Projects,
Table 77: Chronic Urticaria Or Hives - Dormant Projects,
Table 78: Acne Vulgaris - Discontinued Products,
Table 79: Rosacea - Discontinued Products,
Table 80: Chronic Urticaria Or Hives - Discontinued Products,

List of Figures
Figure 1: Number of Products under Development for Acne Vulgaris
Figure 2: Number of Products under Development by Companies, Acne Vulgaris
Figure 3: Number of Products under Development for Rosacea
Figure 4: Number of Products under Development by Companies, Rosacea
Figure 5: Number of Products under Development for Chronic Urticaria Or Hives
Figure 6: Number of Products under Development by Companies, Chronic Urticaria Or Hives
Figure 7: Number of Products by Top 10 Targets, Acne Vulgaris
Figure 8: Number of Products by Stage and Top 10 Targets, Acne Vulgaris
Figure 9: Number of Products by Top 10 Mechanism of Actions, Acne Vulgaris
Figure 10: Number of Products by Stage and Top 10 Mechanism of Actions, Acne Vulgaris
Figure 11: Number of Products by Routes of Administration, Acne Vulgaris
Figure 12: Number of Products by Stage and Routes of Administration, Acne Vulgaris
Figure 13: Number of Products by Molecule Types, Acne Vulgaris
Figure 14: Number of Products by Stage and Molecule Types, Acne Vulgaris
Figure 15: Number of Products by Top 10 Targets, Rosacea
Figure 16: Number of Products by Stage and Top 10 Targets, Rosacea
Figure 17: Number of Products by Top 10 Mechanism of Actions, Rosacea
Figure 18: Number of Products by Stage and Top 10 Mechanism of Actions, Rosacea
Figure 19: Number of Products by Routes of Administration, Rosacea
Figure 20: Number of Products by Stage and Routes of Administration, Rosacea
Figure 21: Number of Products by Molecule Types, Rosacea
Figure 22: Number of Products by Stage and Molecule Types, Rosacea
Figure 23: Number of Products by Targets, Chronic Urticaria Or Hives
Figure 24: Number of Products by Stage and Targets, Chronic Urticaria Or Hives
Figure 25: Number of Products by Mechanism of Actions, Chronic Urticaria Or Hives
Figure 26: Number of Products by Stage and Mechanism of Actions, Chronic Urticaria Or Hives
Figure 27: Number of Products by Routes of Administration, Chronic Urticaria Or Hives
Figure 28: Number of Products by Stage and Top 10 Routes of Administration, Chronic Urticaria Or Hives
Figure 29: Number of Products by Molecule Types, Chronic Urticaria Or Hives
Figure 30: Number of Products by Stage and Molecule Types, Chronic Urticaria Or Hives

Note: Product cover images may vary from those shown
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  • 3SBio Inc
  • Acne Vulgaris
  • BioPharmX Inc
  • Braintree Laboratories Inc
  • Cassiopea SpA
  • Cutanea Life Sciences Inc
  • Daewoong Co Ltd
  • Deltanoid Pharmaceuticals Inc
  • ELORAC Inc
  • Foamix Pharmaceuticals Ltd
  • Galderma SA
  • Helix BioMedix Inc
  • Innovation Pharmaceuticals Inc
  • Lee's Pharmaceutical Holdings Ltd
  • LEO Pharma A/S
  • Melinta Therapeutics Inc
  • Novabiotics Ltd
  • Novan Inc
  • Novartis AG
  • Paratek Pharmaceuticals Inc
  • Pfizer Inc
  • Phagelux Inc
  • Phosphagenics Ltd
  • Photocure ASA
  • Promius Pharma LLC
  • Provectus Biopharmaceuticals Inc
  • Realm Therapeutics Plc
  • Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd
  • Sol-GelTechnologiesLtd
  • Sun Pharmaceutical Industries Ltd
  • Valeant Pharmaceuticals International Inc
  • Vyome Biosciences Pvt Ltd
Note: Product cover images may vary from those shown
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