Somatostatin Receptor Type 4 (SSTR4) - Pipeline Review, H1 2018

  • ID: 4576070
  • Drug Pipelines
  • 38 pages
  • Global Markets Direct
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Somatostatin Receptor Type 4 (SSTR4) - Pipeline Review, H1 2018

Summary:

Somatostatin Receptor Type 4 (SSTR4) pipeline Target constitutes close to 6 molecules. The latest report Somatostatin Receptor Type 4 (SSTR4) - Pipeline Review, H1 2018, outlays comprehensive information on the Somatostatin Receptor Type 4 (SSTR4) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.

Somatostatin Receptor Type 4 (SSTR4) - Somatostatin receptor type 4 is a protein encoded by the SSTR4 gene. The activity of receptor is mediated by G proteins which inhibits adenylyl cyclase. It mediates antiproliferative action of somatostatin in tumor cells. It is functionally coupled to inhibition of adenylate cyclase and activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. The molecules developed by companies in Phase II, Phase I, Preclinical and Discovery stages are 1, 1, 1 and 3 respectively. Report covers products from therapy areas Central Nervous System, Hormonal Disorders, Metabolic Disorders and Oncology which include indications Acromegaly, Chronic Pain, Neuropathic Pain, Neuroendocrine Tumors, Pituitary ACTH Hypersecretion (Cushing Disease), Diabetic Retinopathy, Gastrointestinal Tumor, Inflammatory Pain and Pancreatic Tumor.

Furthermore, this report also reviews key players involved in Somatostatin Receptor Type 4 (SSTR4) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope:
  • The report provides a snapshot of the global therapeutic landscape for Somatostatin Receptor Type 4 (SSTR4)
  • The report reviews Somatostatin Receptor Type 4 (SSTR4) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in Somatostatin Receptor Type 4 (SSTR4) targeted therapeutics and enlists all their major and minor projects
  • The report assesses Somatostatin Receptor Type 4 (SSTR4) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews latest news and deals related to Somatostatin Receptor Type 4 (SSTR4) targeted therapeutics
Reasons for Purchase:
  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for Somatostatin Receptor Type 4 (SSTR4)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding Somatostatin Receptor Type 4 (SSTR4) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
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Introduction

Report Coverage

Somatostatin Receptor Type 4 (SSTR4) - Overview

Somatostatin Receptor Type 4 (SSTR4) - Therapeutics Development

Products under Development by Stage of Development

Products under Development by Therapy Area

Products under Development by Indication

Products under Development by Companies

Somatostatin Receptor Type 4 (SSTR4) - Therapeutics Assessment

Assessment by Mechanism of Action

Assessment by Route of Administration

Assessment by Molecule Type

Somatostatin Receptor Type 4 (SSTR4) - Companies Involved in Therapeutics Development

Centrexion Therapeutics Corp

Crinetics Pharmaceuticals Inc

Strongbridge Biopharma plc

Somatostatin Receptor Type 4 (SSTR4) - Drug Profiles

CNTX-0290 - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecule to Agonize SSTR4 for Chronic Pain and Neuropathic Pain - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Small Molecules to Agonize SSTR2 and SSTR4 for Chronic Pain and Neuropathic Pain - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Synthetic Peptides to Agonize Somatostatin Receptors for Acromegaly - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

veldoreotide - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

veldoreotide MR - Drug Profile

Product Description

Mechanism Of Action

R&D Progress

Somatostatin Receptor Type 4 (SSTR4) - Dormant Products

Somatostatin Receptor Type 4 (SSTR4) - Product Development Milestones

Featured News & Press Releases

Jul 18, 2017: Centrexion Provides Pipeline Updates, Plans for Phase 2 Study of Pain Drug Candidate CNTX-0290

May 31, 2016: Strongbridge Biopharma plc Announces Presentation of COR-005 Data at the European Congress of Endocrinology

Apr 27, 2015: Crinetics Pharmaceuticals Awarded NIH Fast-Track Grant to Develop Somatostatin Receptor Agonist Drugs for Chronic Pain

Apr 22, 2014: Aspireo Reports Data in Further Phase Ib Study

Sep 25, 2013: FDA Grants Orphan Drug Designation for Aspireo’s Somatoprim

Jun 18, 2013: Aspireo Reports Start of Further Phase I Study in Healthy Volunteers

Apr 03, 2013: Aspireo Pharma Reports Somatoprim Phase IIa Proof Of Concept Results In Acromegaly

Jan 07, 2013: Aspireo Pharma Reports Phase Ib Interim Data For Somatoprim

Nov 26, 2012: Aspireo Pharma Announces EMA's Committee For Orphan Medicinal Products Recommends Orphan Medicinal Product Designation For Somatoprim

Nov 06, 2012: Aspireo Pharma Starts Somatoprim Phase IIa Study In Acromegaly Patients

Sep 28, 2012: Evotec And Aspireo Pharma Enter Into Strategic Advisory Agreement For Somatoprim

Jun 26, 2012: Somatoprim is a potent agonist of Somatostatin Receptors 2 and 5

Apr 05, 2012: Aspireo Starts Phase I Multi Ascending Dose Study with Somatoprim

Feb 26, 2009: DeveloGen Reports Positive Phase I Clinical Trial Results for DG3173

Oct 08, 2008: DeveloGen Announces Completion Of A Phase I Clinical Trial Of DG3173, A Novel Somatostatin Analogue For The Treatment Of Acromegaly

Appendix

Methodology

Coverage

Secondary Research

Primary Research

Expert Panel Validation

Contact Us

Disclaimer

List of Tables

Number of Products under Development by Stage of Development, H1 2018

Number of Products under Development by Therapy Areas, H1 2018

Number of Products under Development by Indication, H1 2018

Number of Products under Development by Companies, H1 2018

Products under Development by Companies, H1 2018

Number of Products by Stage and Mechanism of Actions, H1 2018

Number of Products by Stage and Route of Administration, H1 2018

Number of Products by Stage and Molecule Type, H1 2018

Pipeline by Centrexion Therapeutics Corp, H1 2018

Pipeline by Crinetics Pharmaceuticals Inc, H1 2018

Pipeline by Strongbridge Biopharma plc, H1 2018

Dormant Products, H1 2018

Dormant Products, H1 2018 (Contd..1), H1 2018

Dormant Products, H1 2018 (Contd..2), H1 2018

List of Figures

Number of Products under Development by Stage of Development, H1 2018

Number of Products under Development by Therapy Areas, H1 2018

Number of Products under Development by Top 10 Indications, H1 2018

Number of Products by Stage and Mechanism of Actions, H1 2018

Number of Products by Routes of Administration, H1 2018

Number of Products by Stage and Routes of Administration, H1 2018

Number of Products by Molecule Types, H1 2018

Number of Products by Stage and Molecule Types, H1
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  • Centrexion Therapeutics Corp
  • Crinetics Pharmaceuticals Inc
  • Strongbridge Biopharma plc
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