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Antiemetics: Technologies and Global Markets

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    Report

  • 115 Pages
  • July 2018
  • Region: Global
  • BCC Research
  • ID: 4593325
UP TO OFF until Aug 31st 2033

The report details the antiemetic drug market. The analysis highlights current and future market potential for antiemetic drug and presents a detailed review of pipeline drugs, blockbuster drugs, and challenges to market growth. The report also examines disease burden, regulatory environment, novel technologies, and market projections to 2023. Antiemetic drug market drivers, trends and potential regional market opportunities are also covered in this report.

The report details market shares of antiemetic drug class (5-HT3 receptor antagonists, dopamine antagonists, steroid-corticosteroids, benzodiazepines, NK1 receptor antagonist, antihistamines, cannabinoids, and anticholinergic) and geographic market segmentation of overall market; global market share by applications, with special emphasis on developed and underdeveloped geographic regions. For market estimates, data has been provided for 2017, as the base year, 2018 and forecast for 2023.

The Report Includes:


  • 21 data tables and 15 additional tables
  • Country-specific data and analysis for United States, Canada, Mexico, France, Germany, UK, China, India, Japan, and the Middle East and Africa
  • An overview about current and future market potential for antiemetic drugs with special focus on the competitive environment, pipeline drugs and blockbuster drugs
  • Coverage of disease burden, regulatory environment, and novel technologies in the antiemetic drugs market
  • Detailed description about the vestibular disorder and increasing demand of innovative technology for treatment
  • Exploration of the causes of emesis, usage of antiemetics and the types of products available to treat nausea and vomiting by each application segment
  • Information about the launching of new drugs in each antiemetic drug class such as 5 HT3 receptor antagonists, dopamine antagonists, NK1 receptor antagonist, and so forth
  • Detailed company profiles of major players in the market, including Abbott Laboratories, Daiichi Sankyo Company, Ltd., Merck & Co., Novartis AG, Sanofi Aventis and Teva Pharmaceutical Industries Ltd.

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Table of Contents

1 Introduction
  • Antiemetic Technologies
  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Information Sources
  • Methodology
  • Geographic Breakdown
  • Analyst's Credentials
  • Related Reports



2 Summary and Highlights
3 Overview
  • Introduction
  • Causes of Nausea and Vomiting
  • Gastrointestinal Obstruction/Infection/Inflammation
  • Drug-Induced Nausea and Vomiting
  • Pregnancy-Induced Nausea and Vomiting
  • Post-operative Nausea and Vomiting
  • Vestibular Disorder
  • Pathophysiology of Nausea and Vomiting
  • Gastrointestinal Tract
  • Chemoreceptor Trigger Zone
  • Vestibular Apparatus
  • Cerebral Cortex



4 Market and Technology Background
  • Drivers
  • Global Increase in Number of Pregnancies and Burden of Underlying Disease Conditions
  • Increasing in Research Grants and Funding
  • Growing Research Activity in Innovative Antiemetic Drug Therapy
  • Use of Novel Drug Deliveries to Treat Nausea and Vomiting
  • Restraints
  • Lack of Animal Models to Prove Efficacy of Antiemetics
  • Pricing Pressure Experienced by Innovators
  • Availability of Alternative Treatments
  • Opportunities
  • Disease Burden and Increasing Number of Pregnancies in Europe and Asia-Pacific
  • Vestibular Disorders
  • The emergence of Advanced Therapies
  • Patent Expiry



5 Market Breakdown by Drug Class
  • Introduction
  • Global Antiemetic Drugs Market
  • 5-HT3 Receptor Antagonists
  • NK1 Receptor Antagonist
  • Dopamine Antagonists
  • Antihistamines (H1 Receptor Antagonists)
  • Cannabinoids
  • Benzodiazepines
  • Corticosteroids
  • Anticholinergics



6 Market Breakdown by Application
  • Overview
  • Market Size and Forecast
  • Chemotherapy-Induced Nausea and Vomiting
  • Introduction
  • Market Size and Forecast
  • Key CINV Market Takeaways
  • Gastroenteritis
  • Market Size and Forecast
  • Nausea and Vomiting of Pregnancy (NVP)
  • Market Size and Forecast
  • Post-Operative Nausea and Vomiting
  • Market Size and Forecast



7 Market Breakdown by Region
  • Overview
  • Market Size and Forecast
  • North America
  • Market Size and Forecast
  • United States
  • Canada
  • Mexico
  • Europe
  • Market Size and Forecast
  • United Kingdom
  • Germany
  • Asia-Pacific
  • Market Size and Forecast
  • The Middle East and Africa
  • South America



8 Patent Review/New Developments
  • Introduction



9 Pipeline Analysis
  • Introduction
  • NK1 Receptor Antagonists



10 Regulatory Landscape
  • Introduction
  • Regional Regulatory Landscape
  • North America
  • Europe
  • Asia-Pacific



11 Company Profiles
  • ABBOTT LABORATORIES
  • Overview
  • Financial Information
  • Products and Services
  • Development and Strategies
  • ASTELLAS PHARMA INC.
  • Overview
  • Financial Information
  • Products and Services
  • Development and Strategies
  • APHIOS CORP.
  • Overview
  • AUROBINDO PHARMA
  • Overview
  • Financial Information
  • Products and Services
  • DAIICHI SANKYO COMPANY LTD.
  • Overview
  • Financial Information
  • Product and Services
  • Development and Strategies
  • EISAI CO., INC.
  • Overview
  • Financial Information
  • Products and Services
  • GLAXOSMITHKLINE PLC
  • Overview
  • Financial Information
  • Products and Services
  • HELSINN HEALTHCARE SA
  • Overview
  • Products and Services
  • Key Developments and Strategies
  • HERON THERAPEUTICS, INC.
  • Overview
  • Financials
  • Products and Services
  • IPCA LABORATORIES, LTD.
  • Overview
  • KYOWA HAKKO KIRIN PHARMA, INC.
  • Overview
  • Financials
  • MERCK & CO., INC.
  • Overview
  • Financial Information
  • Products and Services
  • NOVARTIS AG
  • Overview
  • Financial Information
  • F. HOFFMANN-LA ROCHE AG
  • Overview
  • Financial Information
  • Products and Services
  • SANOFI AVENTIS
  • Overview
  • Financial Information
  • Products and Services
  • TESARO, INC.
  • Overview
  • Financial Information
  • Products and Services
  • Development and strategies
  • TEVA PHARMACEUTICAL INDUSTRIES LTD.
  • Overview
  • Financial Information
  • Product and Services
  • Development and Strategies



12 Appendix: Abbreviations
List of Tables
Summary Table A Global Antiemetic Drugs Market, by Drug Class, Through 2023
Summary Table B Global Antiemetic Drugs Market, by Application, Through 2023
Table 1 Emetic Potency of Chemotherapeutic Agents
Table 2 Vomiting as Adverse Effect at Therapeutic Dosage
Table 3 Ondansetron Patent Expiration
Table 4 Aloxi Patent Expiration
Table 5 List of FDA approved Antiemetic Drugs and Indications
Table 6 Global Antiemetic Drugs Market, by Drug Class, Through 2023
Table 7 5-HT3 Receptor Drugs
Table 8 FDA Approved Dopamine Antagonists
Table 9 Global Antiemetic Drugs Market, by Application, Through 2023
Table 10 Global Antiemetic Drugs Market, by Region, Through 2023
Table 11 Antiemetic Drug Patents
Table 12 Antiemetic Drug Candidates
Table 13 FDA Approved Drugs
Table 14 List of Antiemetic Drugs Approved in Japan
Table 15 Abbott Laboratories: Net Revenue, 2015-2017
Table 16 Abbott Laboratories: Net Revenue, by Segment, 2017
Table 17 Abbott Laboratories: Marketed Products, 2016
Table 18 Astellas Pharma Inc.: Net Revenue, 2015-2017
Table 19 Astellas Pharma Inc.: Marketed Products, 2016
Table 20 Aurobindo Pharma Ltd.: Net Revenue, 2015-2017
Table 21 Daiichi Sankyo Company Ltd.: Net Revenue, 2015-2017
Table 22 Eisai Co., Inc.: Net Revenue, by Region, 2014-2016
Table 23 Eisai Co., Inc.: Oncology Product Sales, 2014-2016
Table 24 GlaxoSmithKline PLC: Net Revenue, 2014-2016
Table 25 Heron Therapeutics Inc.: Net Revenue, 2016-2017
Table 26 Kyowa Hakko Kirin Pharma Inc.: Net Revenue, 2013-2017
Table 27 Merck & Co. Inc.: Net Revenue, 2014-2016
Table 28 Novartis AG: Net Revenue, 2014-2016
Table 29 F. Hoffmann-La Roche Ltd.: Net Revenue, by Segment, Through 2017
Table 30 Sanofi: Net Revenue, 2014-2016
Table 31 Teva Pharmaceutical Industries Ltd.: Net Revenue, 2015-2017
Table 32 Teva Pharmaceutical Industries Ltd.: Net Revenue, by Segments, 2015-2017
Table 33 Teva Pharmaceutical Industries Ltd: Products and Services
Table 34 Abbreviations
List of Figures
Summary Figure A Global Antiemetic Drugs Market, by Drug Class, 2017-2023
Summary Figure B Global Antiemetic Drugs Market, by Application, 2017-2023
Figure 1 Mechanism of Chemotherapy-Induced Nausea and Vomiting
Figure 2 Pathophysiology of Nausea and Vomiting
Figure 3 Pathophysiology of Emesis
Figure 4 Global Antiemetic Drugs Market, by Drug Class, 2017-2023
Figure 5 Global Market Share of Antiemetics, by Drug Class, 2017
Figure 6 Global 5-HT3 Receptor Market, 2017-2023
Figure 7 Global NK1 Receptor Antagonist Market, 2017-2023
Figure 8 Global Dopamine Receptor Market, 2017-2023
Figure 9 Global Antihistamines Receptor Antagonist Market, 2017-2023
Figure 10 Global Cannabinoids Market, 2017-2023
Figure 11 Global Benzodiazepines Market, 2017-2023
Figure 12 Global Corticosteroid Market, 2017-2023
Figure 13 Global Anticholinergic Drugs Market, 2017-2023
Figure 14 Global Market Share for Antiemetics Drug, by Application, 2017
Figure 15 Global CINV Drugs Market, 2017-2023
Figure 16 Global Gastroenteritis Antiemetic Drug Market, 2017-2023
Figure 17 Global NVP Antiemetic Drug Market, 2017-2023
Figure 18 Global PONV Antiemetic Drugs Market, 2017-2023
Figure 19 Global Antiemetic Drugs Market, by Region, 2017-2023
Figure 20 North America Antiemetic Drugs Market, 2017-2023
Figure 21 North America Antiemetic Drugs Market, by Application, 2017-2023
Figure 22 Europe Antiemetic Drugs Market, 2017-2023
Figure 23 Europe Antiemetic Drugs Market, by Application, 2017-2023
Figure 24 Asia-Pacific Antiemetic Drugs Market, 2017-2023
Figure 25 Asia-Pacific Antiemetic Drugs Market, by Application, 2017-2023
Figure 26 Middle East and Africa Antiemetic Drugs Market, 2017-2023
Figure 27 South America Antiemetic Drugs Market, 2017-2023
Figure 28 Abbott Laboratories: Revenue Share, by Segment, 2017
Figure 29 Astellas Pharma Inc.: Revenue Share, by Segment, 2017
Figure 30 Aurobindo Pharma Ltd.: Revenue Share, by Segment, 2017
Figure 31 Daiichi Sankyo Company Ltd.: Revenue Share, by Business Segment, 2016
Figure 32 GlaxoSmithKline PLC: Revenue Share, by Business Segment, 2016
Figure 33 GlaxoSmithKline PLC: Revenue Share, by Region, 2016
Figure 34 Merck & Co. Inc.: Revenue Share, by Business Segment, 2016
Figure 35 Merck & Co. Inc.: Revenue Share, by Region, 2016
Figure 36 Novartis AG: Revenue Share, by Region, 2016
Figure 37 Novartis AG: Revenue Share, by Business Segment, 2016
Figure 38 F. Hoffmann-La Roche Ltd.: Pharmaceuticals Revenue Share, by Business Segment, 2016
Figure 39 Sanofi: Revenue Share, by Region, 2016
Figure 40 Sanofi: Revenue Share, by Business Segment, 2016
Figure 41 Sanofi: Revenue Share, by Pharmaceuticals Segment, 2017
Figure 42 Tesaro, Inc.: Net Revenue, 2015-2017
Figure 43 Teva Pharmaceutical Industries Ltd.: Generic Medicines Segment Revenue Share, by Region, 2017

Executive Summary

Emesis is a devastating adverse effect of surgery, poisoning, chemotherapy, vestibular imbalance, medication, radiotherapy and during pregnancy. Emesis itself is not a disease but an indication of a stressed physiological condition. During the last decades, extraordinary technological advances have made innovations in most of the disease therapies, including cancer therapies, which is the most common cause of emesis.

The antiemetic drug market is population driven and mostly depends on the number of chemotherapy and radiation therapy sessions performed in specific geographic regions that have high cancer burden and utilize chemotherapy and radiation therapy for cancer treatment. Antiemetics are used to suppress nausea and vomiting associated with CINV, PINV, NVP, RINV, motion sickness and vestibular sickness. 5-HT3 receptor antagonists and NK1 receptor antagonists are the most frequently used antiemetic drug categories.

The 5-HT3 receptor antagonist market accounts for the largest market share of the global antiemetic market. NK1 receptor antagonists are the second largest antiemetic drug segment. Food and Drug Administration(FDA), the commercial launch of new drug candidates, and the existing pipeline which is likely to hit the market in by 2023. Anticholinergics and benzodiazepines are the smallest antiemetic market segments, accounting for approximately REDACTED of the overall market share.

North America is the leading contributor to the antiemetic drug market. The Middle East and Africa antiemetic market are expected to grow at the highest rate during the forecast period.

Companies Mentioned

  • Abbott Laboratories
  • Aphios Corp.
  • Astellas Pharma Inc.
  • Aurobindo Pharma
  • Daiichi Sankyo Company Ltd.
  • Eisai Co., Inc.
  • F. Hoffmann-La Roche Ag
  • Glaxosmithkline Plc
  • Helsinn Healthcare Sa
  • Heron Therapeutics, Inc.
  • IPCA Laboratories, Ltd.
  • Kyowa Hakko Kirin Pharma, Inc.
  • Merck & Co., Inc.
  • Novartis Ag
  • Sanofi Aventis
  • Tesaro, Inc.
  • Teva Pharmaceutical Industries Ltd.