Pancreatic and Bile Duct Cancer Drug Development Pipeline Review, 2018

  • ID: 4618142
  • Report
  • 385 Pages
  • GBI Research
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FEATURED COMPANIES

  • 3-V Biosciences Inc
  • Bionomics Ltd
  • F. Hoffmann-La Roche Ltd
  • Ipsen SA
  • Oasmia Pharmaceutical AB
  • Senhwa Biosciences Inc
  • MORE

Pancreatic cancer is a disease in which malignant (cancer) cells are found in the tissues of the pancreas, a large gland situated in the abdominal cavity that is responsible for the secretion of digestive fluids and insulin.

Signs and symptoms include upper abdominal pain, yellowing of the skin and the whites of the eyes (jaundice), loss of appetite, weight loss, depression and blood clots. Predisposing factors include age, gender, smoking, diabetes and family history. Treatments include surgery, chemotherapy and radiation therapy. There are 759 products in development for this indication.

Bile duct cancer or cholangiocarcinoma are tumors that occur in the bile ducts, a series of tubes in the biliary tract that are essential for the secretion of bile, which plays an important role in digestion. Symptoms include discomfort in the abdomen, loss of appetite, fevers and weight loss. Treatment includes chemotherapy and radiation therapy. There are 133 products in development for this indication.

Molecular targets acted on by products in development for pancreatic and bile duct cancer include vascular endothelial growth factor receptors, programmed cell death protein 1 and signal transducer and activator of transcription 3.

This report “Pancreatic and Bile Duct Cancer Drug Development Pipeline Review, 2018” provides an overview of the pipeline landscape for pancreatic and bile duct cancer. It provides comprehensive information on the therapeutics under development and key players involved in therapeutic development for pancreatic and bile duct cancer, and features dormant and discontinued products.

Scope

  • Which companies are the most active within the pipeline for pancreatic and bile duct cancer?
  • Which pharmaceutical approaches are most prominent at each stage of the pipeline and within each indication?
  • To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
  • What are the most important R&D milestones and data publications to have happened within this field?

Reasons to buy

  • Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
  • Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication, and a comprehensive picture of recent updates and milestones for each
  • Analyze the companies, institutions and universities currently operating in the pipeline, and the products being fielded by each of these
  • Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration
Note: Product cover images may vary from those shown
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FEATURED COMPANIES

  • 3-V Biosciences Inc
  • Bionomics Ltd
  • F. Hoffmann-La Roche Ltd
  • Ipsen SA
  • Oasmia Pharmaceutical AB
  • Senhwa Biosciences Inc
  • MORE

1.1 List of Tables
1.2 List of Figures

2 Introduction

2.1 Pancreatic and Bile Duct Cancer Report Coverage
2.2 Pancreatic Cancer - Overview
2.3 Bile Duct Cancer (Cholangiocarcinoma) - Overview

3 Therapeutics Development

3.1 Pancreatic Cancer
3.2 Bile Duct Cancer (Cholangiocarcinoma)

4 Therapeutics Assessment

4.1 Pancreatic Cancer
4.2 Bile Duct Cancer (Cholangiocarcinoma)

5 Companies Involved in Therapeutics Development

5.1 Pancreatic Cancer
5.2 Bile Duct Cancer (Cholangiocarcinoma)

6 Dormant Projects

6.1 Pancreatic Cancer
6.2 Bile Duct Cancer (Cholangiocarcinoma)

7 Discontinued Products

7.1 Pancreatic Cancer
7.2 Bile Duct Cancer (Cholangiocarcinoma)

8 Product Development Milestones

8.1 Pancreatic Cancer
8.2 Bile Duct Cancer (Cholangiocarcinoma)

9 Appendix

1.1 List of Tables

Table 1: Number of Products under Development for Pancreatic Cancer
Table 2: Number of Products under Development by Companies, Pancreatic Cancer
Table 3: Number of Products under Development by Universities/Institutes, Pancreatic Cancer
Table 4: Products under Development by Companies, Pancreatic Cancer
Table 5: Products under Development by Universities/Institutes, Pancreatic Cancer
Table 6: Number of Products under Development for Bile Duct Cancer (Cholangiocarcinoma)
Table 7: Number of Products under Development by Companies, Bile Duct Cancer (Cholangiocarcinoma)
Table 8: Number of Products under Development by Universities/Institutes, Bile Duct Cancer (Cholangiocarcinoma)
Table 9: Products under Development by Companies, Bile Duct Cancer (Cholangiocarcinoma)
Table 10: Products under Development by Universities/Institutes, Bile Duct Cancer (Cholangiocarcinoma)
Table 11: Number of Products by Stage and Target, Pancreatic Cancer
Table 12: Number of Products by Stage and Mechanism of Action, Pancreatic Cancer
Table 13: Number of Products by Stage and Route of Administration, Pancreatic Cancer
Table 14: Number of Products by Stage and Molecule Type, Pancreatic Cancer
Table 15: Number of Products by Stage and Target, Bile Duct Cancer (Cholangiocarcinoma)
Table 16: Number of Products by Stage and Mechanism of Action, Bile Duct Cancer (Cholangiocarcinoma)
Table 17: Number of Products by Stage and Route of Administration, Bile Duct Cancer (Cholangiocarcinoma)
Table 18: Number of Products by Stage and Molecule Type, Bile Duct Cancer (Cholangiocarcinoma)
Table 19: Pancreatic Cancer - Pipeline by 3-V Biosciences Inc
Table 20: Pancreatic Cancer - Pipeline by 4P-Pharma SAS
Table 21: Pancreatic Cancer - Pipeline by 4SC AG
Table 22: Pancreatic Cancer - Pipeline by AB Science SA
Table 23: Pancreatic Cancer - Pipeline by AbbVie Inc
Table 24: Pancreatic Cancer - Pipeline by AbGenomics International Inc
Table 25: Pancreatic Cancer - Pipeline by Ability Pharmaceuticals SL
Table 26: Pancreatic Cancer - Pipeline by Aclaris Therapeutics Inc
Table 27: Pancreatic Cancer - Pipeline by Actuate Therapeutics Inc
Table 28: Pancreatic Cancer - Pipeline by Adamed Sp z oo
Table 29: Pancreatic Cancer - Pipeline by Aduro BioTech Inc
Table 30: Pancreatic Cancer - Pipeline by Advantagene Inc
Table 31: Pancreatic Cancer - Pipeline by AGV Discovery SAS
Table 32: Pancreatic Cancer - Pipeline by AIMM Therapeutics BV
Table 33: Pancreatic Cancer - Pipeline by Alissa Pharma
Table 34: Pancreatic Cancer - Pipeline by Alligator Bioscience AB
Table 35: Pancreatic Cancer - Pipeline by Allinky Biopharma
Table 36: Pancreatic Cancer - Pipeline by Altor BioScience Corp
Table 37: Pancreatic Cancer - Pipeline by Ambrx Inc
Table 38: Pancreatic Cancer - Pipeline by amcure GmbH
Table 39: Pancreatic Cancer - Pipeline by Amgen Inc
Table 40: Pancreatic Cancer - Pipeline by Amplia Therapeutics Pty Ltd
Table 41: Pancreatic Cancer - Pipeline by Anavex Life Sciences Corp
Table 42: Pancreatic Cancer - Pipeline by Andarix Pharmaceuticals Inc
Table 43: Pancreatic Cancer - Pipeline by ANP Technologies Inc
Table 44: Pancreatic Cancer - Pipeline by AntiCancer Inc
Table 45: Pancreatic Cancer - Pipeline by APEIRON Biologics AG
Table 46: Pancreatic Cancer - Pipeline by Apexigen Inc
Table 47: Pancreatic Cancer - Pipeline by Aphios Corp
Table 48: Pancreatic Cancer - Pipeline by Aposense Ltd
Table 49: Pancreatic Cancer - Pipeline by ARMO Biosciences Inc
Table 50: Pancreatic Cancer - Pipeline by ArQule Inc

1.2 List of Figures

Figure 1: Number of Products under Development for Pancreatic Cancer
Figure 2: Number of Products under Development by Companies, Pancreatic Cancer
Figure 3: Number of Products under Development by Universities/Institutes, Pancreatic Cancer
Figure 4: Number of Products under Development for Bile Duct Cancer (Cholangiocarcinoma)
Figure 5: Number of Products under Development by Companies, Bile Duct Cancer (Cholangiocarcinoma)
Figure 6: Number of Products under Development by Universities/Institutes, Bile Duct Cancer (Cholangiocarcinoma)
Figure 7: Number of Products by Top 10 Targets, Pancreatic Cancer
Figure 8: Number of Products by Stage and Top 10 Targets, Pancreatic Cancer
Figure 9: Number of Products by Top 10 Mechanism of Actions, Pancreatic Cancer
Figure 10: Number of Products by Stage and Top 10 Mechanism of Actions, Pancreatic Cancer
Figure 11: Number of Products by Top 10 Routes of Administration, Pancreatic Cancer
Figure 12: Number of Products by Stage and Top 10 Routes of Administration, Pancreatic Cancer
Figure 13: Number of Products by Top 10 Molecule Types, Pancreatic Cancer
Figure 14: Number of Products by Stage and Top 10 Molecule Types, Pancreatic Cancer
Figure 15: Number of Products by Top 10 Targets, Bile Duct Cancer (Cholangiocarcinoma)
Figure 16: Number of Products by Stage and Top 10 Targets, Bile Duct Cancer (Cholangiocarcinoma)
Figure 17: Number of Products by Top 10 Mechanism of Actions, Bile Duct Cancer (Cholangiocarcinoma)
Figure 18: Number of Products by Stage and Top 10 Mechanism of Actions, Bile Duct Cancer (Cholangiocarcinoma)
Figure 19: Number of Products by Routes of Administration, Bile Duct Cancer (Cholangiocarcinoma)
Figure 20: Number of Products by Stage and Routes of Administration, Bile Duct Cancer (Cholangiocarcinoma)
Figure 21: Number of Products by Top 10 Molecule Types, Bile Duct Cancer (Cholangiocarcinoma)
Figure 22: Number of Products by Stage and Top 10 Molecule Types, Bile Duct Cancer (Cholangiocarcinoma)

Note: Product cover images may vary from those shown
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  • 3-V Biosciences Inc
  • 4P-Pharma SAS
  • 4SC AG
  • AB Science SA
  • AbbVie Inc
  • AbGenomics International Inc
  • Ability Pharmaceuticals SL
  • Aclaris Therapeutics Inc
  • Actuate Therapeutics Inc
  • Adamed Sp z oo
  • Aduro BioTech Inc
  • Advantagene Inc
  • Advenchen Laboratories LLC
  • Agios Pharmaceuticals Inc
  • AGV Discovery SAS
  • AIMM Therapeutics BV
  • Alissa Pharma
  • Alligator Bioscience AB
  • Allinky Biopharma
  • Altor BioScience Corp
  • Ambrx Inc
  • amcure GmbH
  • Amgen Inc
  • Amplia Therapeutics Pty Ltd
  • Anavex Life Sciences Corp
  • Andarix Pharmaceuticals Inc
  • ANP Technologies Inc
  • AntiCancer Inc
  • APEIRON Biologics AG
  • Apexigen Inc
  • Aphios Corp
  • Aposense Ltd
  • Ariad Pharmaceuticals Inc
  • ARMO Biosciences Inc
  • ArQule Inc
  • Array BioPharma Inc
  • Asana BioSciences LLC
  • Aslan Pharmaceuticals Pte Ltd
  • Astellas Pharma Inc
  • AstraZeneca Plc
  • Aurigene Discovery Technologies Ltd
  • AVEO Pharmaceuticals Inc
  • Axcentua Pharmaceuticals AB
  • Basilea Pharmaceutica Ltd
  • Bavarian Nordic A/S
  • Bayer AG
  • BeiGene Ltd
  • Bellicum Pharmaceuticals Inc
  • Berg LLC
  • BerGenBio ASA
  • Bexion Pharmaceuticals LLC
  • BeyondSpring Pharmaceuticals Inc
  • Bile Duct Cancer (Cholangiocarcinoma)
  • BioAtla LLC
  • BioLineRx Ltd
  • BioMoti Ltd
  • Biomunex Pharmaceuticals
  • Bionomics Ltd
  • BioNTech AG
  • Bio-Path Holdings Inc
  • Biothera Pharmaceutical Inc
  • Biouniversa srl
  • BLR Bio LLC
  • Boehringer Ingelheim GmbH
  • Boston Biomedical Inc
  • BriaCell Therapeutics Corp
  • Bristol-Myers Squibb Co
  • Calithera Biosciences Inc
  • Cancer Prevention Pharmaceuticals Inc
  • Cantargia AB
  • Cantex Pharmaceuticals Inc
  • CARsgen Therapeutics Ltd
  • CBT Pharmaceuticals Inc
  • CCRP Therapeutics GmbH
  • Celgene Corp
  • Celldex Therapeutics Inc
  • Cellectar Biosciences Inc
  • Celleron Therapeutics Ltd
  • Cellestia Biotech AG
  • Cellular Biomedicine Group Inc
  • Celprogen Inc
  • Celyad SA
  • Centrose LLC
  • Chem-Master International Inc
  • ChemoCentryx Inc
  • Chugai Pharmaceutical Co Ltd
  • Clovis Oncology Inc
  • COARE Biotechnology Inc
  • Codiak BioSciences Inc
  • Concordia International Corp
  • Corcept Therapeutics Inc
  • Cotinga Pharmaceuticals Inc
  • CPL Biologicals Pvt Ltd
  • CrystalGenomics Inc
  • CTI BioPharma Corp
  • Cyclacel Pharmaceuticals Inc
  • CytImmune Sciences Inc
  • CytomX Therapeutics Inc
  • Cytori Therapeutics Inc
  • CyTuVax BV
  • Daewoong Pharmaceutical Co Ltd
  • Daiichi Sankyo Co Ltd
  • Debiopharm International SA
  • DEKK-TEC Inc
  • Delcath Systems Inc
  • Denceptor Therapeutics Ltd
  • Diffusion Pharmaceuticals Inc
  • Eddingpharm Inc
  • Eisai Co Ltd
  • Eleison Pharmaceuticals LLC
  • Eli Lilly and Co
  • Endor Nanotechnologies SL
  • Ensol Biosciences Inc
  • Enterome Bioscience SA
  • Erytech Pharma SA
  • Esperance Pharmaceuticals Inc
  • Etubics Corp
  • Exelixis Inc
  • F. Hoffmann-La Roche Ltd
  • Faron Pharmaceuticals Oy
  • Felicitex Therapeutics Inc
  • FibroGen Inc
  • Formation Biologics Inc
  • Formosa Laboratories Inc
  • Forty Seven Inc
  • Fountain Biopharma Inc
  • Fujifilm Holdings Corporation
  • Fusion Antibodies Ltd
  • Galera Therapeutics Inc
  • GamaMabs Pharma SA
  • Geistlich Pharma AG
  • Genelux Corp
  • Genentech Inc
  • Genisphere LLC
  • Genmab A/S
  • Genoscience Pharma
  • Gilead Sciences Inc
  • GlaxoSmithKline Plc
  • GlycoMimetics Inc
  • Glycotope GmbH
  • Golden Biotechnology Corp
  • GW Pharmaceuticals Plc
  • H3 Biomedicine Inc
  • Halozyme Therapeutics Inc
  • Heidelberg Pharma AG
  • Helix BioPharma Corp
  • Hemispherx Biopharma Inc
  • Horizon Pharma Plc
  • Hutchison MediPharma Ltd
  • Icell Kealex Therapeutics LLC
  • Idera Pharmaceuticals Inc
  • Igenica Biotherapeutics Inc
  • Ignyta Inc
  • Immix BioPharma Inc
  • Immodulon Therapeutics Ltd
  • Immune System Key Ltd
  • Immunitor Inc
  • Immunomedics Inc
  • Immunotope Inc
  • Immunovo BV
  • Immupharma Plc
  • Incyte Corp
  • Inflection Biosciences Ltd
  • Innopharmax Inc
  • Innovation Pharmaceuticals Inc
  • Inovio Pharmaceuticals Inc
  • InteRNA Technologies BV
  • Intezyne Technologies Inc
  • Inventiva
  • InvivoGen Therapeutics
  • Io Therapeutics Inc
  • Iovance Biotherapeutics Inc
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  • ISU ABXIS Co Ltd
  • Jasco Pharmaceuticals LLC
  • Jiangsu Hengrui Medicine Co Ltd
  • Johnson & Johnson
  • Juno Therapeutics Inc
  • Kalyra Pharmaceuticals Inc
  • Karcinolys SAS
  • Karyopharm Therapeutics Inc
  • Kazia Therapeutics Ltd
  • Keystone Nano Inc
  • Komipharm International Co Ltd
  • Kringle Pharma Inc
  • Kuhnil Pharmaceutical Co Ltd
  • Kura Oncology Inc
  • Kyowa Hakko Kirin Co Ltd
  • Lead Discovery Center GmbH
  • Leap Therapeutics Inc
  • Lexicon Pharmaceuticals Inc
  • LIfT BioSciences Ltd
  • Lixte Biotechnology Holdings Inc
  • Loxo Oncology Inc
  • Lymphocyte Activation Technologies SA
  • MabVax Therapeutics Holdings Inc
  • Machavert Pharmaceuticals LLC
  • MacroGenics Inc
  • MaxiVAX SA
  • Meabco AS
  • Mebiopharm Co Ltd
  • MediaPharma SRL
  • Medicenna Therapeutics Corp
  • MediciNova Inc
  • MedImmune LLC
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  • Merck KGaA
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  • MetaMax Ltd
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  • NanoVector Inc
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  • Nascent Biotech Inc
  • Natco Pharma Ltd
  • NatureWise Biotech & Medicals Corp
  • NBE-Therapeutics AG
  • Nektar Therapeutics
  • Nerviano Medical Sciences Srl
  • NewLink Genetics Corp
  • NormOxys Inc
  • Northern Biologics Inc
  • Northwest Biotherapeutics Inc
  • Novartis AG
  • Noxxon Pharma AG
  • NuCana Plc
  • Oasmia Pharmaceutical AB
  • OBI Pharma Inc
  • Omeros Corp
  • Oncodesign SA
  • Oncology Research International Ltd
  • Oncolytics Biotech Inc
  • Oncomatryx Biopharma SL
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  • tella Inc
  • Tesaro Inc
  • Tiziana Life Sciences Plc
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  • Transgene SA
  • Trovagene Inc
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  • Vaximm AG
  • Vaxon Biotech
  • VCN Biosciences SL
  • Vect-Horus SAS
  • Verastem Inc
  • VG Life Sciences Inc
  • Vicus Therapeutics LLC
  • Viralytics Ltd
  • Virobay Inc
  • ViroStatics srl
  • XBiotech Inc
  • XuanZhu Pharma Co Ltd
  • Zeria Pharmaceutical Co Ltd
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