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Celiac Disease - Pipeline Review, H2 2020

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    Drug Pipelines

  • 96 Pages
  • September 2020
  • Region: Global
  • Global Markets Direct
  • ID: 5174815
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Summary

The publisher's latest Pharmaceutical and Healthcare disease pipeline guide Celiac Disease - Pipeline Review, H2 2020, provides an overview of the Celiac Disease (Gastrointestinal) pipeline landscape.

Celiac disease is an autoimmune disorder caused by an immune response to wheat protein gluten. Symptoms include weight loss, vomiting, abdominal bloating, abdominal pain and persistent diarrhea. Risk factors include lupus, rheumatoid arthritis, type 1 diabetes, autoimmune liver disease, Sjogren’s syndrome and Turner syndrome. Treatment includes steroids such as betamethasone and prednisolone. Further the treatment regime also involves adhering to strict gluten free diet.

Report Highlights

The publisher's Pharmaceutical and Healthcare latest pipeline guide Celiac Disease - Pipeline Review, H2 2020, provides comprehensive information on the therapeutics under development for Celiac Disease (Gastrointestinal), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Celiac Disease (Gastrointestinal) pipeline guide also reviews of key players involved in therapeutic development for Celiac Disease and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical and Discovery stages are 1, 4, 4, 1, 5 and 8 respectively. Similarly, the Universities portfolio in Phase I stages comprises 1 molecules, respectively.

Celiac Disease (Gastrointestinal) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from the publisher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content/sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Celiac Disease (Gastrointestinal).
  • The pipeline guide reviews pipeline therapeutics for Celiac Disease (Gastrointestinal) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Celiac Disease (Gastrointestinal) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Celiac Disease (Gastrointestinal) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Celiac Disease (Gastrointestinal)

Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Celiac Disease (Gastrointestinal).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Celiac Disease (Gastrointestinal) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

Introduction
  • Report Coverage

Celiac Disease - Overview
Celiac Disease - Therapeutics Development
  • Pipeline Overview
  • Pipeline by Companies
  • Pipeline by Universities/Institutes
  • Products under Development by Companies
  • Products under Development by Universities/Institutes

Celiac Disease - Therapeutics Assessment
  • Assessment by Target
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type

Celiac Disease - Companies Involved in Therapeutics Development
9 Meters Biopharma Inc
  • Ahead Therapeutics SL
  • Amgen Inc
  • Amyra Biotech AG
  • Anokion SA
  • AnTolRx Inc
  • Bioniz Therapeutics Inc
  • GlaxoSmithKline Plc
  • ImCyse SA
  • ImmunogenX LLC
  • ImmunoMolecular Therapeutics LLC
  • ImmusanT Inc
  • Parvus Therapeutics Inc
  • Precigen Inc
  • Protagonist Therapeutics Inc
  • Takeda Pharmaceutical Co Ltd
  • Theravance Biopharma Inc
  • Topas Therapeutics GmbH
  • Vactech Oy
  • Zedira GmbH

Celiac Disease - Drug Profiles
AG-017 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

AMG-714 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

AMY-01 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

AT-1715 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Biologic for Celiac Disease - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

BNZ-2 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

BNZ-3 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Drug to Agonize Aryl Hydrocarbon Receptor for Celiac Disease - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

ERW-1041E - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

KAN-101 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

larazotide acetate - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

latiglutenase - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Monoclonal Antibody to Antagonize IL-2R Beta for Celiac Disease, Oncology and Tropical Spastic Paraparesis - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Nexvax-2 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

PTG-100 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Recombinant Peptides for Celiac Disease - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Small Molecules to Inhibit HLA-DQ2 for Celiac Disease - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Synthetic Peptide for Celiac Disease - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

TAK-062 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

TAK-101 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

TD-5202 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Vaccine for Celiac Disease - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

ZED-1227 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

ZED-754 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Celiac Disease - Dormant ProjectsCeliac Disease - Discontinued Products
Celiac Disease - Product Development Milestones
  • Featured News & Press Releases
  • Sep 22, 2020: Beyond Celiac partners with Provention Bio on phase 2 clinical Trial for promising celiac disease therapeutic
  • Aug 31, 2020: Provention Bio announces initiation of phase 2b PROACTIVE study of PRV-015 (anti-IL-15) in non-responsive celiac disease
  • Jun 29, 2020: 9 Meters Biopharma amends definition of primary endpoint for phase 3 trial in celiac disease after consultation with FDA
  • May 11, 2020: 9 Meters Biopharma receives thorough QT study waiver by FDA for Larazotide being studied for celiac disease
  • Feb 27, 2020: Anokion announces initiation of patient dosing in Phase 1 clinical trial of KAN-101 in celiac disease
  • Feb 19, 2020: Innovate Biopharmaceuticals announces acceptance of three abstracts for the 2020 Digestive Disease Week (DDW) conference
  • Feb 14, 2020: ImmunogenX starts enrolment in Phase IIb celiac disease study
  • Jan 21, 2020: Anokion announces FDA clearance of IND application for its lead program in celiac disease
  • Oct 22, 2019: Takeda Pharmaceutical: New treatment may reverse celiac disease
  • Aug 19, 2019: ActoBio Therapeutics receives IND green light for new antigen-specific immunotherapy study aimed at improving celiac patients tolerance of gluten
  • Aug 13, 2019: Innovate Biopharmaceuticals announces first patient dosed in the first phase 3 clinical trial for patients with celiac disease
  • Jul 15, 2019: Innovate Biopharmaceuticals announces corporate update and expected date for second quarter earnings release
  • Jun 25, 2019: ImmusanT discontinues phase 2 clinical trial for Nexvax2 in patients with celiac disease
  • Jun 24, 2019: Innovate Biopharmaceuticals expands its management team with the addition of Ed Sitar as Its Chief Financial Officer
  • Jun 10, 2019: Innovate Biopharmaceuticals announces the start of the first phase 3 clinical trial in Celiac Disease

Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact
  • Disclaimer

List of Tables
  • Number of Products under Development for Celiac Disease, H2 2020
  • Number of Products under Development by Companies, H2 2020
  • Number of Products under Development by Companies, H2 2020 (Contd..1), H2 2020
  • Number of Products under Development by Universities/Institutes, H2 2020
  • Products under Development by Companies, H2 2020
  • Products under Development by Companies, H2 2020 (Contd..1), H2 2020
  • Products under Development by Universities/Institutes, H2 2020
  • Number of Products by Stage and Target, H2 2020
  • Number of Products by Stage and Mechanism of Action, H2 2020
  • Number of Products by Stage and Route of Administration, H2 2020
  • Number of Products by Stage and Molecule Type, H2 2020
  • Celiac Disease - Pipeline by 9 Meters Biopharma Inc, H2 2020
  • Celiac Disease - Pipeline by Ahead Therapeutics SL, H2 2020
  • Celiac Disease - Pipeline by Amgen Inc, H2 2020
  • Celiac Disease - Pipeline by Amyra Biotech AG, H2 2020
  • Celiac Disease - Pipeline by Anokion SA, H2 2020
  • Celiac Disease - Pipeline by AnTolRx Inc, H2 2020
  • Celiac Disease - Pipeline by Bioniz Therapeutics Inc, H2 2020
  • Celiac Disease - Pipeline by GlaxoSmithKline Plc, H2 2020
  • Celiac Disease - Pipeline by ImCyse SA, H2 2020
  • Celiac Disease - Pipeline by ImmunogenX LLC, H2 2020
  • Celiac Disease - Pipeline by ImmunoMolecular Therapeutics LLC, H2 2020
  • Celiac Disease - Pipeline by ImmusanT Inc, H2 2020
  • Celiac Disease - Pipeline by Parvus Therapeutics Inc, H2 2020
  • Celiac Disease - Pipeline by Precigen Inc, H2 2020
  • Celiac Disease - Pipeline by Protagonist Therapeutics Inc, H2 2020
  • Celiac Disease - Pipeline by Takeda Pharmaceutical Co Ltd, H2 2020
  • Celiac Disease - Pipeline by Theravance Biopharma Inc, H2 2020
  • Celiac Disease - Pipeline by Topas Therapeutics GmbH, H2 2020
  • Celiac Disease - Pipeline by Vactech Oy, H2 2020
  • Celiac Disease - Pipeline by Zedira GmbH, H2 2020
  • Celiac Disease - Dormant Projects, H2 2020
  • Celiac Disease - Dormant Projects, H2 2020 (Contd..1), H2 2020
  • Celiac Disease - Discontinued Products, H2 2020

List of Figures
  • Number of Products under Development for Celiac Disease, H2 2020
  • Number of Products under Development by Companies, H2 2020
  • Number of Products by Top 10 Targets, H2 2020
  • Number of Products by Stage and Top 10 Targets, H2 2020
  • Number of Products by Top 10 Mechanism of Actions, H2 2020
  • Number of Products by Stage and Top 10 Mechanism of Actions, H2 2020
  • Number of Products by Routes of Administration, H2 2020
  • Number of Products by Stage and Routes of Administration, H2 2020
  • Number of Products by Top 10 Molecule Types, H2 2020
  • Number of Products by Stage and Top 10 Molecule Types, H2 2020

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • 9 Meters Biopharma Inc
  • Ahead Therapeutics SL
  • Amgen Inc
  • Amyra Biotech AG
  • Anokion SA
  • AnTolRx Inc
  • Bioniz Therapeutics Inc
  • GlaxoSmithKline Plc
  • ImCyse SA
  • ImmunogenX LLC
  • ImmunoMolecular Therapeutics LLC
  • ImmusanT Inc
  • Parvus Therapeutics Inc
  • Precigen Inc
  • Protagonist Therapeutics Inc
  • Takeda Pharmaceutical Co Ltd
  • Theravance Biopharma Inc
  • Topas Therapeutics GmbH
  • Vactech Oy
  • Zedira GmbH