1h Free Analyst TimeKOL Perspectives: Cardiovascular safety profile of JAK inhibitors in Rheumatoid Arthritis
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This KOL Insight briefing focuses on KOL opinions of the safety of JAK inhibitors in rheumatoid arthritis (RA).
The briefing includes analysis of KOL opinion on the following topic areas:
- Baricitinib safety profile with regards to cardiovascular signal
- Tofacitinib safety profile with regards to cardiovascular signal
- Upadacitinib safety profile with regards to cardiovascular signal
- Filgotinib safety profile with regards to cardiovascular signal
- Most favorable JAK inhibitor with regards to cardiovascular safety
- Extent in which thromboembolic events is a class effect across all JAK inhibitors
- Additional studies / actions required to mitigate concerns around cardiovascular safety in the JAK inhibitors class
- Majority of KOLs acknowledged that there was a CV signal with baricitinib in RA, although many flagged this was not necessarily a concern
- While KOLs generally had a positive opinion of tofacitinib’s CV risk profile, many stated the need for more safety data
- Most KOLs highlighted the need for additional data before drawing conclusions regarding upadacitinib’s CV safety profile.
- The insight briefing is based on Sociable Pharma’s analysis of primary research with our RA key opinion leaders (KOLs)
- In total, we conducted interviews with 10 KOLs: Five Europe-based & five US-based
- Interviews conducted in December 2017
- KOL data is analyzed to produce: Charts summarizing KOL opinions
- Chart call-outs of key information & details
- KOL quotes
- Summary of KOL reporting trends
- Insight from Sociable Pharma's analysts.
Reasons to buy
- Combines Qualitative & semi-quantitative insight from key opinion leaders on "Cardiovascular safety profile of JAK inhibitors in Rheumatoid Arthritis".
- Includes insight & recommendations from our disease-specific healthcare analysts
- Utilizes independent expert viewpoints to validate the impact of new clinical data & emerging trends on management of rheumatoid arthritis
- Provides cost-effective support for your advisory boards, with topics acting as a catalyst for further expert discussion.
Table of ContentsExecutive Summary
Research Panel Composition
Results & Implications
A selection of companies mentioned in this report includes: