Drug Overview
Thalomid (Celgene) contains thalidomide, a glutamic acid derivative that possesses immunomodulatory, anti-inflammatory, and anti-angiogenic properties.
The drug’s mechanism of action is not fully understood, but it is presumed to inhibit both the production of tumor necrosis factor-alpha in stimulated peripheral monocytes, and the activities of interleukins and interferons.
It also exhibits pro-angiogenic effects and is found to inhibit both the vascular endothelial growth factor and basic fibroblast growth factor.
Thalomid (Celgene) contains thalidomide, a glutamic acid derivative that possesses immunomodulatory, anti-inflammatory, and anti-angiogenic properties.
The drug’s mechanism of action is not fully understood, but it is presumed to inhibit both the production of tumor necrosis factor-alpha in stimulated peripheral monocytes, and the activities of interleukins and interferons.
It also exhibits pro-angiogenic effects and is found to inhibit both the vascular endothelial growth factor and basic fibroblast growth factor.
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