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Thalomid

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    Report

  • 20 Pages
  • August 2018
  • Region: Global
  • Citeline
  • ID: 4775171
Drug Overview
Thalomid (Celgene) contains thalidomide, a glutamic acid derivative that possesses immunomodulatory, anti-inflammatory, and anti-angiogenic properties.

The drug’s mechanism of action is not fully understood, but it is presumed to inhibit both the production of tumor necrosis factor-alpha in stimulated peripheral monocytes, and the activities of interleukins and interferons.

It also exhibits pro-angiogenic effects and is found to inhibit both the vascular endothelial growth factor and basic fibroblast growth factor.

Table of Contents

OVERVIEW
Drug Overview
Product Profiles
Thalomid : Multiple myeloma
LIST OF FIGURES
Figure 1: Thalomid for multiple myeloma – SWOT analysis
Figure 2: The authors drug assessment summary of Thalomid for multiple myeloma
Figure 3: The authors drug assessment summary of Thalomid for multiple myeloma
Figure 4: Thalomid sales for multiple myeloma across the US, Japan, and five major EU markets, by country, 2017–26
LIST OF TABLES
Table 1: Thalomid drug profile
Table 2: Thalomid pivotal trial data in multiple myeloma
Table 3: Thalomid late-phase trial data in multiple myeloma
Table 4: Thalomid sales for multiple myeloma across the US, Japan, and five major EU markets, by country ($m), 2017–26
Table 5: Patients treated with Thalomid across the US, Japan, and five major EU markets, by country, 2017–26