Drug Overview
Ozanimod (Celgene) is a sphingosine 1-phosphate (S1P) receptor agonist, with selectivity for the sphingosine 1-phosphate type 1 receptor (S1P1) and sphingosine 1-phosphate receptor 5 (S1P5).
The drug modulates the expression of S1P receptors, which is thought to reduce the overall number of circulating lymphocytes by preventing their migration from secondary lymphoid organs.
The drug is being developed in multiple sclerosis, ulcerative colitis, and Crohn’s disease.
Ozanimod (Celgene) is a sphingosine 1-phosphate (S1P) receptor agonist, with selectivity for the sphingosine 1-phosphate type 1 receptor (S1P1) and sphingosine 1-phosphate receptor 5 (S1P5).
The drug modulates the expression of S1P receptors, which is thought to reduce the overall number of circulating lymphocytes by preventing their migration from secondary lymphoid organs.
The drug is being developed in multiple sclerosis, ulcerative colitis, and Crohn’s disease.
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