Organ-on-a-Chip: Global Markets - Research and Markets

Report Scope

The scope of this report covers various types of products available in the organ-on-a-chip market and potential application sectors in various industries. The organ-on-a-chip market is broken down into various segments. Revenue forecasts from 2019 to 2026 are given for each type, application, offering and end user. Revenue generated from the installation and maintenance of instruments has been excluded from the report. The application segment is characterized by various types, including drug discovery and development, toxicological research, and physiological model development, and by end-use industry, including academic and research institutes, pharmaceutical and biotechnology companies, cosmetics industry and other end users. By type market is segmented to liver, lung, kidney, heart and others. The report also focuses on regional segmentation of the market.Further, it explains the major drivers and regional dynamics of the global market and current trends within the industry. It also includes information about the industry structure and competitive landscape as well as the impact of COVID-19 on the market. The report includes detailed profiles of the major players in the global organ-on-a-chip market.

Report Includes

55 data tables and 29 additional tables
An up-to-date review and analysis of the global markets for organ-on-a-chip within the biotech industry
Analyses of the global market trends, with data from 2019 to 2021, and projections of compound annual growth rates (CAGRs) through 2026
Information on multi-channel 3-D microfluidic cell culture chip, and discussion of their ability to imitate human microenvironment in vitro
Evaluation and forecast the global organ-on-a-chip market size, and corresponding market share analysis by technology offering, organ type, application, end-user vertical and region
Discussion on how organ-on-a-chip is emerging as a priority testing alternative which is replacing animals in life science research, toxicology testing and drug development studies
Review of potential applications in pharmaceutical and life science research sectors, including preclinical drugs testing, drug screening, personalized medicine, phenotypic screening, lead optimization and disease modelling
Insights into the recent industry structure including the government programs and policies in support of organ-on-a-chip and coverage of revised laws involving animal testing
Review of patent grants for innovations in organ-on-a-chip technology across each major category
Descriptive company profiles of the leading global players, including 4Dcell, BiomimX, Emulate Inc., Kirkstall Ltd., Nortis and TissUse GmbH

Chapter 1 Introduction

Study Goals and Objectives
Reasons for Doing this Study
What's New in this Update?
Scope of Report
Information Sources
Methodology
Geographic Breakdown
Analyst's Credentials
Custom Research
Related Research Reports

Chapter 2 Summary and Highlights

Chapter 3 Market and Technology Background

Introduction
Developments in Drug Discovery
1950-1970
1970-1990
1990-2010
2010 to the Present
Market Potential
Strategic Initiatives
Regulatory Framework
U.S.
European Union
China
Japan

Chapter 4 Market Dynamics

Factors Affecting the Organ-On-A-Chip Market
Market Drivers
Increasing Incidence of Chronic Diseases
Rising Demand for a Way to Enhance the Effectiveness of Clinical Trials
Increasing Investments for Drug Research and Development
Increasing Demand for Personalized Medicine
Market Restraints
Lack of Standardization

Chapter 5 Impact of Covid-19

Introduction
Outbreak Origins
Symptoms of Covid-19
Progression of Covid-19
Incubation Period
Epidemiology
Collaboration Between Organizations and Governments
Spread of Disease
Impact of Covid-19 on the Organ-On-A-Chip Market

Chapter 6 Global Organ-On-A-Chip Market by Type

Liver
Liver-On-A-Chip Classifications Depending on Their Principal Actions
Heart
Kidney
Lung
Other Organs

Chapter 7 Global Organ-On-A-Chip Market by End-user

Biotechnology and Pharmaceutical Companies
Cosmetics Industry
Academic and Research Institutes
Increasing R&D Spending
Other End-users

Chapter 8 Global Organ-On-A-Chip Market by Offering

Products
Services

Chapter 9 Global Organ-On-A-Chip Market by Application

Drug Discovery and Development
Toxicological Research
Physiological Model Development

Chapter 10 Global Organ-On-A-Chip Market by Region

North America
U.S.
Canada
Europe
U.K.
France
Germany
Spain
Rest of Europe
Asia-Pacific
China
Japan
India
Australia
Rest of the World

Chapter 11 Industry Structure

Raw Material Suppliers
Quality and Technology
Terms and Conditions
Cost-Effective Components
Manufacturers
Distributors
End-users of Consumables
Competitive Analysis
Patent Landscape
Patent Review by Year
Patent Review by Country

Chapter 12 Company Profiles

4Dcell
Axosim
Beonchip
Biomimx
Bioivt
Cherry Biotech
Cn Bio
Elveflow
Emulate Inc.
Fluigent
Hesperos Inc.
Hurel Corp.
Insphero
Kirkstall
Mesobio Tech
Micronit
Mimetas
Nortis
Synvivo
Tara Biosystems Inc.
Tissuse Gmbh

List of Tables

Summary Table: Global Organ-on-a-Chip Market, Through 2026
Table 1: Drug Development Time Span
Table 2: Advantages of Organ-on-a-Chip Compared to Traditional Methods of Drug Discovery
Table 3: U.S. NIH Funding of Research for Various Diseases, 2014-2020
Table 4: Distribution of COVID-19 Clinical Symptoms
Table 5: COVID-19 Cases, by WHO Region, February 18, 2022
Table 6: Global Organ-on-a-Chip Market, Through 2026
Table 7: Global Organ-on-a-Chip Market, by Type, Through 2026
Table 8: Liver-on-a-Chip Classifications
Table 9: Global Liver Organ-on-a-Chip Market, by Region, Through 2026
Table 10: Global Heart Organ-on-a-Chip Market, by Region, Through 2026
Table 11: Deaths from CVD and Number of People Living with CVD in U.K., 2020
Table 12: Global Kidney Organ-on-a-Chip Market, by Region, Through 2026
Table 13: Global Burden of Chronic Kidney Disease, 2010 and 2019
Table 14: Global Lung Organ-on-a-Chip Market, by Region, Through 2026
Table 15: Mortality Rates Due to Leading Respiratory Causes, 2019
Table 16: Global Market for Other Types of Organ-on-a-Chip, by Region, Through 2026
Table 17: Global Organ-on-a-Chip Market, by End User, Through 2026
Table 18: Global Biotechnology and Pharmaceutical Company Revenues from the Organ-on-a-Chip Market, by Region, Through 2026
Table 19: Biopharmaceuticals R&D Spending, 2010-2024
Table 20: Global Cosmetics Industry Revenues from the Organ-on-a-Chip Market, by Region, Through 2026
Table 21: Global Academic and Research Institution Revenues from the Organ-on-a-Chip Market, by Region, Through 2026
Table 22: Cancer Research Grants, by Cancer Type, August 2021
Table 23: Global Prevalence of Dementia, 2020-2050
Table 24: Global Market for Other End Users of Organ-on-a-Chip, by Region, Through 2026
Table 25: Global Organ-on-a-Chip Market, by Offering, Through 2026
Table 26: Global Organ-on-a-Chip Products Market, by Region, Through 2026
Table 27: Global Organ-on-a-Chip Services Market, by Region, Through 2026
Table 28: Global Organ-on-a-Chip Market, by Application, Through 2026
Table 29: Global Pharmaceutical Market, 2019 and 2020
Table 30: Pharmaceutical Spending as a Percentage of Total Healthcare Spending, by Country, 2019
Table 31: PhRMA Member Company, Global R&D Spending, 2015-2019
Table 32: Medicines in Development, 2018
Table 33: Global Market for Organ-on-a-Chip in Drug Discovery and Development, by Region, Through 2026
Table 34: Global Market for Organ-on-a-Chip in Toxicological Research, by Region, Through 2026
Table 35: Total Number of New Cases and Deaths Due to Various Cancers Globally, 2020
Table 36: Global Market for Organ-on-a-Chip in Physiological Model Development, by Region, Through 2026
Table 37: Global Organ-on-a-Chip Market, by Region, Through 2026
Table 38: North American Organ-on-a-Chip Market, by Type, Through 2026
Table 39: North American Organ-on-a-Chip Market, by Application, Through 2026
Table 40: North American Organ-on-a-Chip Market, by End User, Through 2026
Table 41: North American Organ-on-a-Chip Market, by Offering, Through 2026
Table 42: NIH Spending on Stem Cell Research in the U.S., 2015-2020
Table 43: Shares of the Annual Budget of the Canadian Institutes of Health Research, by Type of Research, 2020
Table 44: European Organ-on-a-Chip Market, by Type, Through 2026
Table 45: European Organ-on-a-Chip Market, by Application, Through 2026
Table 46: European Organ-on-a-Chip Market, by End User, Through 2026
Table 47: European Organ-on-a-Chip Market, by Offering, Through 2026
Table 48: R&D Expenditure in Spain, 2015 and 2019
Table 49: Asia-Pacific Organ-on-a-Chip Market, by Type, Through 2026
Table 50: Asia-Pacific Organ-on-a-Chip Market, by Application, Through 2026
Table 51: Asia-Pacific Organ-on-a-Chip Market, by End User, Through 2026
Table 52: Asia-Pacific Organ-on-a-Chip Market, by Offering, Through 2026
Table 53: R&D Spending, by India’s Top Pharma Companies, 2018
Table 54: Rest of the World Organ-on-a-Chip Market, by Type, Through 2026
Table 55: Rest of the World Organ-on-a-Chip Market, by Application, Through 2026
Table 56: Rest of the World Organ-on-a-Chip Market, by End User, Through 2026
Table 57: Rest of the World Organ-on-a-Chip Market, by Offering, Through 2026
Table 58: Raw Material/Part Manufacturers
Table 59: Competitive Analysis of Organ-on-a-Chip Market, 2020
Table 60: Patent Review of Organ-on-a-Chip, 2018-2021
Table 61: Patent Review of Organ-on-a-Chip, by Country, 2018-2021
Table 62: 4Dcell: Product Portfolio
Table 63: AxoSim Inc.: Product Portfolio
Table 64: BEOnChip: Product Portfolio
Table 65: BiomimX: Product Portfolio
Table 66: BiomimX: Product Pipeline
Table 67: BioIVT: Product Portfolio
Table 68: Cherry Biotech: Product Portfolio
Table 69: CN Bio: Product Portfolio
Table 70: Elveflow: Product Portfolio
Table 71: Emulate Inc.: Product Portfolio
Table 72: Fluigent: Research Product Portfolio
Table 73: Hesperos Inc.: Product Portfolio
Table 74: Hurel Corp.: Product Portfolio
Table 75: InSphero: Product Portfolio
Table 76: Kirkstall Ltd.: Product Portfolio
Table 77: MesoBio Tech: Product Portfolio
Table 78: Micronit: Product Portfolio
Table 79: Mimetas B.V.: Product Portfolio
Table 80: Nortis: Product Portfolio
Table 81: SynVivo: Product Portfolio
Table 82: Tara Biosystems Inc.: Product Portfolio
Table 83: TissUse GmbH: Product Portfolio

List of Figures

Summary Figure: Global Organ-on-a-Chip Market, 2019-2026
Figure 1: Development of Organ-on-a-Chip
Figure 2: Drug Development Process
Figure 3: FDA Stages of New Medicine Review and Regulation
Figure 4: Research and Development Process of a Drug
Figure 5: Global Pharmaceutical R&D Spending, 2010-2019
Figure 6: Personalized Medicines on Market, 2008-2020
Figure 7: Global Organ-on-a-Chip Market, 2019-2026
Figure 8: Global Organ-on-a-Chip Market, by Type, 2019-2026
Figure 9: Global Liver Organ-on-a-Chip Market, by Region, 2019-2026
Figure 10: Global Heart Organ-on-a-Chip Market, by Region, 2019-2026
Figure 11: Share of Heart Disease Deaths in the U.S., by Disease Type, 2021
Figure 12: Global Kidney Organ-on-a-Chip Market, by Region, 2019-2026
Figure 13: Global Lung Organ-on-a-Chip Market, by Region, 2019-2026
Figure 14: Global Market for Other Types of Organ-on-a-Chip, by Region, 2019-2026
Figure 15: Organ-on-a-Chip Market, by End Users
Figure 16: Global Organ-on-a-Chip Market, by End User, 2019-2026
Figure 17: Major Factors Driving the Growth of the Organ-on-a-Chip Market
Figure 18: Global Biotechnology and Pharmaceutical Company Revenues from the Organ-on-a-Chip Market, by Region, 2019-2026
Figure 19: Biopharmaceuticals R&D Spending, 2010-2024
Figure 20: Global Cosmetics Industry Revenues from the Organ-on-a-Chip Market, by Region, 2019-2026
Figure 21: Global Academic and Research Institution Revenues from the Organ-on-a-Chip Market, by Region, 2019-2026
Figure 22: Shares of Global R&D Funding, by Region, 2020
Figure 23: Top Ten Countries’ R&D Expenditures, 2020
Figure 24: Global Market for Other End Users of Organ-on-a-Chip, by Region, 2019-2026
Figure 25: Global Organ-on-a-Chip Market, by Offering, 2019-2026
Figure 26: Key Products: Organ-on-a-Chip
Figure 27: Global Organ-on-a-Chip Products Market, by Region, 2019-2026
Figure 28: Global Organ-on-a-Chip Services Market, by Region, 2019-2026
Figure 29: Global Organ-on-a-Chip Market, by Application, 2019-2026
Figure 30: Global Pharmaceutical Market Shares, by Region, 2020
Figure 31: Pharmaceutical Spending as a Percentage of Total Healthcare Spending, by Country, 2019
Figure 32: PhRMA Member Company, Global R&D Spending, 2015-2019
Figure 33: Global Market for Organ-on-a-Chip in in Drug Discovery and Development, by Region, 2019-2026
Figure 34: Global Market for Organ-on-a-Chip in Toxicological Research, by Region, 2019-2026
Figure 35: Global Prevalence of Cancer, by Type, 2019
Figure 36: Global Market for Organ-on-a-Chip in Physiological Model Development, by Region, 2019-2026
Figure 37: Global Organ-on-a-Chip Market, by Region, 2019-2026
Figure 38: North American Organ-on-a-Chip Market, by Type, 2019-2026
Figure 39: North American Organ-on-a-Chip Market, by Application, 2019-2026
Figure 40: North American Organ-on-a-Chip Market, by End User, 2019-2026
Figure 41: North American Organ-on-a-Chip Market, by Offering, 2019-2026
Figure 42: NIH Spending on Stem Cell Research in the U.S., 2015-2020
Figure 43: Shares of the Annual Budget of the Canadian Institute of Health Research, by Type of Research, 2020
Figure 44: European Organ-on-a-Chip Market, by Type, 2019-2026
Figure 45: European Organ-on-a-Chip Market, by Application, 2019-2026
Figure 46: European Organ-on-a-Chip Market, by End User, 2019-2026
Figure 47: European Organ-on-a-Chip Market, by Offering, 2019-2026
Figure 48: R&D Expenditure in Spain, 2015 and 2019
Figure 49: Asia-Pacific Organ-on-a-Chip Market, by Type, 2019-2026
Figure 50: Asia-Pacific Organ-on-a-Chip Market, by Application, 2019-2026
Figure 51: Asia-Pacific Organ-on-a-Chip Market, by End User, 2019-2026
Figure 52: Asia-Pacific Organ-on-a-Chip Market, by Offering, 2019-2026
Figure 53: R&D Spending, by India’s Top Pharma Companies, 2018
Figure 54: Rest of the World Organ-on-a-Chip Market, by Type, 2019-2026
Figure 55: Rest of the World Organ-on-a-Chip Market, by Application, 2019-2026
Figure 56: Rest of the World Organ-on-a-Chip Market, by End User, 2019-2026
Figure 57: Rest of the World Organ-on-a-Chip Market, by Offering, 2019-2026
Figure 58: Industry Structure of Instruments Used in the Organ-on-a-Chip Market
Figure 59: Patent Shares of Organ-on-a-Chip, by Year, 2018-2021
Figure 60: Patent Review of Organ-on-a-Chip, by Country, 2018-2021

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Executive Summary

An organ-on-a-chip is a type of artificial organ that possesses the capability to simulate activities, mechanics and physiological responses similar to that of an organ system. These are multi-channel 3D microfluidic cell culture chips that are primarily being used in life science and drug development research because of their ability to imitate human microenvironments in vitro. The unique characteristics of organ-on-a-chip are worked out by integrating biology and advanced engineering. Cell biology, microfluidics and microfabrication are the core fields that have paved the way towards the development of organ-on-a-chip technology.

Organ-on-a-chip is considered to be a potential game-changing technology and is serving as a testing alternative that is replacing the use of animals in life science research, toxicology testing and drug development studies around the globe. Countries are focusing on this upcoming technology to produce safer and effective drugs. It has been observed that pharmaceutical R&D expenses create a lot of burden on the healthcare industry because the drug discovery process requires huge investment but has a low success rate. Studies have indicated that using organ-on-a-chips for drug discovery and development studies will help to reduce the cost by 26% because many ineffective and toxic drugs can be eliminated
at the preclinical stage before they enter human trials. Also, rising demand for personalized medicines is also a contributing factor to growth in the organ-on-a-chip market. There are many diseases that still do not have any approved therapies for cures and depend only on symptomatic management, e.g., amyotrophic lateral sclerosis, cirrhosis, etc. Therefore, organ-on-a-chip will be beneficial for such indications. More research and the increasing prevalence of cancer as well as neurogenerativediseases such as Alzheimer’s, Parkinson’s disease and other rare indications will also be contributing factors for the market.

The North American region has the highest share of the organ-on-a-chip market, followed by Europe. This is because of the extensive research and developmental activities taking place in the region as well as the presence of major players, funding and the increasing prevalence of chronic diseases. All these factors contribute to growth in the organ-on-a-chipmarket.

It has been observed that the COVID-19 pandemichad a positive impact on the organ-on-a-chip market. This is because, due to the pandemic, many institutions across the world began research projects aimed at gaining an understanding of disease pathology and developing treatment options for coronavirus. Finally, it has also been observed that companies are now moving from single organ on a chip to multiple organ on a chip to gain a better understanding of the toxicological impact of a drug.

Companies Mentioned

4Dcell
Axosim
Beonchip
Bioivt
Biomimx
Cherry Biotech
Cn Bio
Elveflow
Emulate Inc.
Fluigent
Hesperos Inc.
Hurel Corp.
Insphero
Kirkstall
Mesobio Tech
Micronit
Mimetas
Nortis
Synvivo
Tara Biosystems Inc.
Tissuse Gmbh

Table Information

Report Attribute	Details
No. of Pages	158
Published	March 2022
Forecast Period	2021 - 2026
Estimated Market Value ( $ ) in 2021	$ 32 Million
Forecasted Market Value ( $ ) by 2026	$ 183.4 Million
Compound Annual Growth Rate	41.8%
Regions Covered	Global
No. of Companies Mentioned	21

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Report Scope

Report Includes

Table of Contents

Samples

Executive Summary

Companies Mentioned

Table Information

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