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Vagus Nerve Stimulators Market Size, Market Share, Application Analysis, Regional Outlook, Growth Trends, Key Players, Competitive Strategies and Forecasts, 2023 to 2031

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    Report

  • 120 Pages
  • April 2023
  • Region: Global
  • Acute Market Reports
  • ID: 5790053
From 2023 to 2031, the global vagus nerve stimulation market is projected to expand at a CAGR of 10.5%. The rising geriatric population, the introduction of technologically advanced products, the escalating product demand as an add-on therapy, the rising incidence of chronic diseases such as migraine and epilepsy, and the presence of unmet medical needs in these disease segments are some of the key factors driving the market growth. The vagus nerve stimulator, also known as the brain's pacemaker, is a device that generates electrical impulses to stimulate the vagus nerve. These electric impulses travel to the brain and are dispersed to various regions to alter the activity of nerves, thereby ensuring that brain cells function properly. The vagus nerve contains 20% efferent fibers and 80% afferent fibers. Efferent fibers are responsible for transmitting signals from the brain to the body, whereas afferent fibers are sensory and carry information from the body to the brain. The vagus nerve is the principal nerve of the parasympathetic nervous system, which regulates specific involuntary bodily functions including digestion, heart rate, and immunity. Vagus nerve stimulators can be used to treat a variety of neurological conditions, including epilepsy, depression, anxiety, cluster headache, migraine, Crohn's disease, and dystonia. Vagus nerve stimulators can also be utilized as a stroke rehabilitation aid.

The Increasing Prevalence of Neurological Disorders

According to data published by the World Health Organization (WHO) in September 2021, depression is a prevalent mental disorder, affecting an estimated 5.0% of adults and 5.7% of adults older than 60 years worldwide in 2019. According to the same source, approximately 280 million people worldwide suffered from depression in 2018-2019. In addition, an estimated 14.8 million adults aged 18 and older in the United States experienced at least one major depressive episode with severe impairment in 2020. This represented 6.0% of all American adults. In addition, according to the American Headache Society, migraine is one of the leading causes of disability in the United States and the third most common disorder worldwide. In addition, according to the Migraine Research Foundation, migraine affects approximately 39 million Americans and 1 billion people worldwide in 2019.

Widespread use of VNS for the treatment of epilepsy. Genealogical factors, head injuries, strokes, brain tumors, and infectious diseases can all contribute to the onset of epilepsy. A study conducted by the International League Against Epilepsy (ILAE) indicates that VNS is effective in reducing seizures in a subset of patients with epilepsy. In addition, it may be an effective adjunctive therapy for patients who have not responded to other treatments. In the coming years, the market expansion is anticipated to be fueled by the aging of the population. Epilepsy, head injuries, and strokes are prevalent among individuals over 65 years old.

Development of Innovative and Efficient Vagus Nerve Stimulators

Technological advancements have led to the creation of vagus nerve stimulators that are more effective. The vagus nerve is stimulated precisely and selectively by these devices, which can be adapted to specific patient needs. To increase their vagus nerve stimulator market share, industry suppliers are launching compact and portable products.

Advanced technology-based vagus nerve stimulators enable a more individualized treatment approach. Additionally, they may be more effective in reducing the frequency and severity of particular conditions. To enable remote monitoring services and stimulation setting adjustments, manufacturers are incorporating IoT features such as Bluetooth connectivity and smartphone app integration. Shortly, the availability of IoT-enabled products will likely boost market statistics.

In September 2020, for instance, ReShape Lifesciences Inc., a U.S. weight-loss and metabolic health solutions company, announced a positive pre-clinical result for its Diabetes Bloc-Stim Neuromodulation (DBSN) device, a dual vagus nerve stimulator for the treatment of type 2 diabetes mellitus.

Key market participants are concentrating on obtaining regulatory approvals for their vagus nerve stimulators, which is anticipated to drive the growth of the global vagus nerve stimulators market during the forecast period.

In April 2020, for instance, electroCore, Inc., a U.S. medical technology company, announced that the U.S. Food and Drug Administration had approved an expanded indication for gammaCore, a non-invasive vagus nerve stimulator, to include migraine prevention in adult patients. Previously, gammaCore was recommended as an adjunctive therapy for cluster headaches and pain management in cases of episodic cluster headaches and migraine headaches.

The shift in Focus to Minimally Invasive VNS Procedures

Implantable VNS has been observed to be associated with surgically-related infections and abnormal complications such as dysrhythmia, cough, paresthesia, pain, and voice alteration, the prevalence of which decreases over time. In this decade, companies such as Cerbomed and Electrocore have made commendable strides in their product research to introduce noninvasive vagus nerve stimulators to the world to combat the side effects of implantable vagus nerve stimulators. Initially, the devices were introduced in Europe. With recent FDA approvals and clearances for the marketing and licensing of noninvasive vagus nerve stimulator products, the devices have made progress and are gaining acceptance worldwide for various neurological treatments. As it does not require implantation, the external vagus nerve stimulator is anticipated to provide an advanced hygienic and noninfectious profile. In addition, external VNS devices are more effective as a treatment and more affordable for patients.

Vagus Nerve Stimulators' adoption will be hindered by their expensive upkeep and devices

Twenty (19%) of 105 patients treated with a vagus nerve stimulator system between 1999 and 2008 experienced device-related technical failures and complications, according to a study. In eight instances of device failure, the device was removed first. Others also experienced complications associated with the device, including electrode malfunction, the onset of wound infections and cardiac arrhythmia, and posttraumatic stimulator dysfunction. Vagus nerve stimulator therapy is also associated with an extensive list of potential side effects. Other concurrent technical failures include dislocation and generator malfunctions. In children, electrode fracture is the leading cause of the most serious complication, which may be caused by growth during adolescence.

As soon as the neurologist prescribes vagus nerve stimulation therapy as a treatment option for any neurological disorder, the question of how much this therapy cost arises. The current cost of vagus nerve stimulator therapy, including the implant and surgical procedure, is high. The costs of surgery and postoperative care may vary across regions of the globe and rise over time. In the West, many insurance companies, including Medicare and the majority of Medicaid providers, cover nearly all costs associated with vagus nerve stimulator therapy. Those who qualify for vagus nerve stimulator therapy but lack insurance coverage or external funds must pay the entire cost of the implant out of pocket, creating a long-term financial burden for the patient.

Global Market for Vagus Nerve Stimulators - Restriction

The risks of technical failures and the high cost of vagus nerve stimulators are expected to restrain the growth of the global vagus nerve stimulators market during the forecast period. According to an article published in June 2018 by the World Neurosurgery Journal, a monthly peer-reviewed medical journal, complications associated with vagus nerve stimulators can include lead fracture, disconnection, battery displacement, and device malfunction. A 25-year-old male patient (United States) with an implanted vagal nerve stimulator for epilepsy complained of neck pain whenever he turned his head to the right. Investigation revealed that the vagal nerve stimulator had a partial lead fracture, necessitating the replacement of the implant. Furthermore, according to an April 2017 article published in the peer-reviewed medical journal Epilepsia, the use of vagus nerve stimulators is associated with both early and late-stage complications. Approximately 66% of patients with implanted vagus nerve stimulators experience laryngopharyngeal dysfunction.

VNS Devices Dominated the Product Market

Due to an increase in the number of patients suffering from various types of headaches, depression, and epilepsy, the implantable VNS device segment dominated the market in 2022 with a revenue share of more than 60%. The implanted VNS devices are designed to act directly on the pain site and alter nerve activity by sending electrical stimulation to a specific nerve, thereby making the disease treatment more effective. The market for vagus nerve stimulation is segmented by product into implantable and external VNS devices.

Those who have not responded to anti-seizure medications and intensive depression treatments, such as antidepressant medications, psychotherapy, and electroconvulsive therapy, may benefit from an implantable VNS device (ECT). In addition, the introduction of new and innovative products by leading market participants is driving the demand for and adoption of VNS devices in the global market. In August 2021, for instance, the FDA approved the MicroTransponderVivistim Paired VNS System, a drug rehabilitation system designed to treat moderate to severe upper extremity motor deficits caused by a chronic ischemic stroke. From 2023 to 2031, the external VNS device segment is expected to grow at the highest CAGR of 12%. This is due to the growing number of patients with chronic disorders, the rising demand for non-invasive therapy, and the device's affordability. During the forecast period, the introduction of new devices by market participants and the shift in patient preference toward non-invasive devices are expected to fuel demand for these devices and drive market growth.

Implantable VNS devices are frequently associated with both surgical and electrical stimulation-related adverse events. Consequently, non-invasive VNS (nVNS) devices were developed to address the deficiencies of their invasive counterparts. Among the commercially available noninvasive vagus nerve stimulators is the gammaCore Sapphire by electroCore and the Parasym device by Parasym Ltd.

Metallic Biomaterials Dominated the Market

The metallic biomaterials segment dominated the market with a revenue share of over 50% in 2022, due to advances and growth in vagus nerve stimulation therapy research and development. It is also anticipated that the segment will maintain its position through 2030. Due to their thermal conductivity and mechanical properties, metallic biomaterials are widely used in medical devices such as implantable devices. Due to their anti-inflammatory properties, 316L stainless steel, titanium-based alloys, gold, tantalum, silver, platinum, and cobalt-chromium alloys are used to coat electrical implantable devices.

The market is segmented by biomaterial into polymeric, metallic, and ceramic biomaterials. The polymeric segment is anticipated to grow at the highest rate from 2023 to 2031, at 11.6%, due to its flexibility advantages. The prevalence of stress and depression continues to rise worldwide. Polymers are capable of regenerating damaged neural tissues and can be fashioned into support structures such as electro-spun matrices, nerve conduits, and scaffolds. Polymers are utilized in medical implantable devices and offer a wide variety of shapes and mechanical properties, including biocompatibility and bioactivity. These factors are anticipated to drive segment expansion over the forecast period.

Epilepsy Segment Remains the Dominant Application Market

As of 2022, the epilepsy segment holds a 60% revenue share, owing to the increasing number of regulatory approvals and the high prevalence of epilepsy around the world. According to the WHO, approximately 49 out of 100,000 people in high-income countries are diagnosed annually with epilepsy, compared to 139 in low- and middle-income countries. Similarly, between 100,000 and 120,000 children are hospitalized annually in the United States due to epilepsy-related conditions. This is anticipated to fuel segment expansion in the coming years. In addition, increasing levels of awareness regarding epilepsy treatment, combined with strategic alliances, are anticipated to stimulate market expansion. Epilepsy networks' awareness campaigns have increased the demand for more accurate disease diagnosis and effective treatment. In 2009, for instance, the Epilepsy Association of Nova Scotia and the Anita Kaufmann Foundation jointly proclaimed March 26 as "Purple Day" to raise global awareness about epilepsy. The vagus nerve stimulation market is segmented by application into epilepsy, depression, and migraine.

From 2023 to 2031, the depression segment is anticipated to grow at the highest compound annual growth rate. The prevalence of stress and depression continues to rise worldwide. According to the National Institute of Mental Health (NIMH), more than 2.7 million American adults are burdened by depression which is difficult to treat. In addition, according to the WHO, more than 300 million adults worldwide suffer from depression, and roughly one-third of patients with major depressive disorder (MDD) have depression that is resistant to treatment (TRD). It has been demonstrated that vagus nerve stimulators play an important role in providing therapeutic solutions for difficult-to-treat depression; thus, an increase in the prevalence of such diseases is anticipated to drive segment growth over the forecast period. In addition, the introduction of technologically advanced products improves the quality of therapy. In 2017, electroCore introduced gammaCore, the first non-invasive vagus nerve stimulation therapy product. These developments are likely to further stimulate segment expansion.

Hospitals Dominated the End User Segment

In 2022, hospitals dominated the end-use segment of the vagus nerve stimulation market with 52%. The expansion is primarily attributable to a rise in the number of VNS surgeries performed in hospitals and the incidence of neurological disorders. In addition, the availability of technologically advanced devices and favorable reimbursement policies are anticipated to boost the hospital segment during the forecast period. For example, Medtronic provides comprehensive services to secure and maintain coverage and payment for a variety of DBS devices. In addition, hospitals are currently advancing in terms of technology, and advanced medical devices are widely used to improve patient care. These devices not only simplify treatment procedures, but also contribute to better, faster, and more precise outcomes. All neurological disorders, including epilepsy, are typically diagnosed and treated by neurologists in specialized hospitals using cutting-edge technology.

In contrast, the Ambulatory Surgical Centers (ASC) segment is anticipated to grow at the fastest CAGR between 2023 and 2030. This is due to the lower cost of procedures compared to hospitals, the ease of access to patient care, the reduction in waiting time, and the low infection rate in comparison to neurology clinics and hospitals. Moreover, according to a study conducted by Advancing Surgical Care, 92% of patients were satisfied with the medical care and service provided by ASCs, thereby contributing to the segment's growth.

In addition, the majority of neuro surgeries can now be performed in ASCs due to the advanced and minimally invasive nature of the surgical procedures performed there. Thus, the segment's growth is primarily attributable to shorter procedure times and ongoing developments in minimally invasive surgical techniques.

North America Remained the Global Leader

North America dominated the vagus nerve stimulation market with a 60% share in 2022, due to an increase in government funding and initiatives for raising awareness about epilepsy and difficult-to-treat depression. In addition, rapid technological advancements, the presence of major manufacturers in the region, an increase in R&D investments, and an increase in government funding and initiatives are expected to create significant growth opportunities in the market. According to the Centers for Medicare & Medicaid Services (CMS), health spending in the United States is projected to increase by 5.5% annually between 2018 and 2027, reaching USD 6 trillion by 2027. In addition, the large market share of the North American region is due in part to the availability of skilled professionals and the high disposable income in developed economies.

Asia-Pacific, on the other hand, is anticipated to grow at a 12% CAGR between 2023 and 2031. This is due to the increasing prevalence of neurodegenerative disorders in the region, as well as the unmet demand for effective and long-lasting solutions. Rising awareness of neurological disease treatment options and enhancements to the clinical development framework of emerging economies are anticipated to drive market expansion in this region. In addition, the presence of high-growth opportunities in developing nations such as Japan, China, and India is likely to contribute to the expansion of the market. In addition, the establishment of organizations such as the Asia-Pacific Centre for Neuromodulation (APCN), which has been established to conduct research and raise awareness about the benefits of vagus nerve stimulation, is anticipated to stimulate regional growth.

Product Launches and Technological Advancements to Enhance Market Share

To strengthen their market position, industry leaders are increasingly focusing on product launches, technological advances, and other growth strategies, such as mergers and acquisitions. For instance, LivaNova received CE Mark approval for their VNS Therapy System - Symmetry - for difficult-to-treat depression in March 2020.

In collaboration with research institutions, market participants are conducting several clinical trials to investigate and expand the applications of VNS devices. However, the demonstrated efficacy of VNS in the treatment of epilepsy and treatment-resistant depression (TRD), as well as the increased prevalence of these devices for epilepsy treatment in developed nations, are anticipated to create significant opportunities for market participants.

On the market for vagus nerve stimulation, newcomers such as electroCore, MicroTransponder, Inc., and Parasym are considered innovators. These companies offer products with a favorable price-to-performance ratio, competitive functionality, and cutting-edge technology. These participants prioritize product commercialization and fundraising to support the expansion of R&D. For example, in November 2017, electroCore completed its Series B Funding round with more than USD 70 million for the commercialization of gammaCore and the continued clinical development of nVNS. The following are some of the leading companies in the global vagus nerve stimulation market: electroCore, Cerebral Rx, MicroTransponder, Inc., Parasym, LivaNova LLC (formerly Cyberonics), and Other Notable Players.

Historical & Forecast Period

This study report represents analysis of each segment from 2021 to 2031 considering 2022 as the base year. Compounded Annual Growth Rate (CAGR) for each of the respective segments estimated for the forecast period of 2022 to 2031.

The current report comprises of quantitative market estimations for each micro market for every geographical region and qualitative market analysis such as micro and macro environment analysis, market trends, competitive intelligence, segment analysis, porters five force model, top winning strategies, top investment markets, emerging trends and technological analysis, case studies, strategic conclusions and recommendations and other key market insights.

Research Methodology

The complete research study was conducted in three phases, namely: secondary research, primary research, and expert panel review. key data point that enables the estimation of Vagus Nerve Stimulators market are as follows:
  • Research and development budgets of manufacturers and government spending
  • Revenues of key companies in the market segment
  • Number of end users and consumption volume, price and value.
  • Geographical revenues generate by countries considered in the report
  • Micro and macro environment factors that are currently influencing the Vagus Nerve Stimulators market and their expected impact during the forecast period.
Market forecast was performed through proprietary software that analyzes various qualitative and quantitative factors. Growth rate and CAGR were estimated through intensive secondary and primary research. Data triangulation across various data points provides accuracy across various analyzed market segments in the report. Application of both top down and bottom-up approach for validation of market estimation assures logical, methodical and mathematical consistency of the quantitative data.

Market Segmentation

Product

  • Implantable VNS Device
  • External VNS Device

Application

  • Epilepsy
  • Depression
  • Migraine

Biomaterial

  • Metallic
  • Ceramics
  • Polymeric

End-use

  • Hospitals
  • Neurology Clinics
  • Ambulatory Surgical Centers
  • Research Centers

Key questions answered in this report

  • What are the key micro and macro environmental factors that are impacting the growth of Vagus Nerve Stimulators market?
  • What are the key investment pockets with respect to product segments and geographies currently and during the forecast period?
  • Estimated forecast and market projections up to 2031.
  • Which segment accounts for the fastest CAGR during the forecast period?
  • Which market segment holds a larger market share and why?
  • Are low and middle-income economies investing in the Vagus Nerve Stimulators market?
  • Which is the largest regional market for Vagus Nerve Stimulators market?
  • What are the market trends and dynamics in emerging markets such as Asia Pacific, Latin America, and Middle East & Africa?
  • Which are the key trends driving Vagus Nerve Stimulators market growth?
  • Who are the key competitors and what are their key strategies to enhance their market presence in the Vagus Nerve Stimulators market worldwide?


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Table of Contents

1. Preface
1.1. Report Description
1.1.1. Purpose of the Report
1.1.2. Target Audience
1.1.3. Key Offerings
1.2. Market Segmentation
1.3. Research Methodology
1.3.1. Phase I - Secondary Research
1.3.2. Phase II - Primary Research
1.3.3. Phase III - Expert Panel Review
1.3.4. Assumptions
1.3.5. Approach Adopted
2. Executive Summary
2.1. Market Snapshot: Global Vagus Nerve Stimulators Market
2.2. Global Vagus Nerve Stimulators Market, By Product, 2022 (US$ Million)
2.3. Global Vagus Nerve Stimulators Market, By Application, 2022 (US$ Million)
2.4. Global Vagus Nerve Stimulators Market, By Biomaterial, 2022 (US$ Million)
2.5. Global Vagus Nerve Stimulators Market, By End-use, 2022 (US$ Million)
2.6. Global Vagus Nerve Stimulators Market, By Geography, 2022 (US$ Million)
2.7. Attractive Investment Proposition by Geography, 2022
3. Vagus Nerve Stimulators Market: Competitive Analysis
3.1. Market Positioning of Key Vagus Nerve Stimulators Market Vendors
3.2. Strategies Adopted by Vagus Nerve Stimulators Market Vendors
3.3. Key Industry Strategies
3.4. Tier Analysis 2022 Versus 2031
4. Vagus Nerve Stimulators Market: Macro Analysis & Market Dynamics
4.1. Introduction
4.2. Global Vagus Nerve Stimulators Market Value, 2021 - 2031, (US$ Million)
4.3. Market Dynamics
4.3.1. Market Drivers
4.3.2. Market Restraints
4.3.3. Key Challenges
4.3.4. Key Opportunities
4.4. Impact Analysis of Drivers and Restraints
4.5. See-Saw Analysis
5. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
5.1. Market Overview
5.2. Growth & Revenue Analysis: 2022 Versus 2031
5.3. Market Segmentation
5.3.1. Implantable VNS Device
5.3.2. External VNS Device
6. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
6.1. Market Overview
6.2. Growth & Revenue Analysis: 2022 Versus 2031
6.3. Market Segmentation
6.3.1. Epilepsy
6.3.2. Depression
6.3.3. Migraine
7. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
7.1. Market Overview
7.2. Growth & Revenue Analysis: 2022 Versus 2031
7.3. Market Segmentation
7.3.1. Metallic
7.3.2. Ceramics
7.3.3. Polymeric
8. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
8.1. Market Overview
8.2. Growth & Revenue Analysis: 2022 Versus 2031
8.3. Market Segmentation
8.3.1. Hospitals
8.3.2. Neurology Clinics
8.3.3. Ambulatory Surgical Centers
8.3.4. Research Centers
9. North America Vagus Nerve Stimulators Market, 2021-2031, USD (Million)
9.1. Market Overview
9.2. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
9.3. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
9.4. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
9.5. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
9.6.Vagus Nerve Stimulators Market: By Region, 2021-2031, USD (Million)
9.6.1.North America
9.6.1.1. U.S.
9.6.1.1.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
9.6.1.1.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
9.6.1.1.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
9.6.1.1.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
9.6.1.2. Canada
9.6.1.2.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
9.6.1.2.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
9.6.1.2.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
9.6.1.2.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
9.6.1.3. Rest of North America
9.6.1.3.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
9.6.1.3.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
9.6.1.3.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
9.6.1.3.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
10. UK and European Union Vagus Nerve Stimulators Market, 2021-2031, USD (Million)
10.1. Market Overview
10.2. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
10.3. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
10.4. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
10.5. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
10.6.Vagus Nerve Stimulators Market: By Region, 2021-2031, USD (Million)
10.6.1.UK and European Union
10.6.1.1. UK
10.6.1.1.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
10.6.1.1.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
10.6.1.1.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
10.6.1.1.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
10.6.1.2. Germany
10.6.1.2.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
10.6.1.2.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
10.6.1.2.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
10.6.1.2.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
10.6.1.3. Spain
10.6.1.3.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
10.6.1.3.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
10.6.1.3.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
10.6.1.3.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
10.6.1.4. Italy
10.6.1.4.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
10.6.1.4.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
10.6.1.4.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
10.6.1.4.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
10.6.1.5. France
10.6.1.5.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
10.6.1.5.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
10.6.1.5.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
10.6.1.5.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
10.6.1.6. Rest of Europe
10.6.1.6.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
10.6.1.6.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
10.6.1.6.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
10.6.1.6.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
11. Asia Pacific Vagus Nerve Stimulators Market, 2021-2031, USD (Million)
11.1. Market Overview
11.2. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
11.3. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
11.4. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
11.5. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
11.6.Vagus Nerve Stimulators Market: By Region, 2021-2031, USD (Million)
11.6.1.Asia Pacific
11.6.1.1. China
11.6.1.1.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
11.6.1.1.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
11.6.1.1.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
11.6.1.1.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
11.6.1.2. Japan
11.6.1.2.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
11.6.1.2.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
11.6.1.2.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
11.6.1.2.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
11.6.1.3. India
11.6.1.3.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
11.6.1.3.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
11.6.1.3.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
11.6.1.3.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
11.6.1.4. Australia
11.6.1.4.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
11.6.1.4.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
11.6.1.4.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
11.6.1.4.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
11.6.1.5. South Korea
11.6.1.5.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
11.6.1.5.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
11.6.1.5.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
11.6.1.5.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
11.6.1.6. Rest of Asia Pacific
11.6.1.6.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
11.6.1.6.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
11.6.1.6.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
11.6.1.6.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
12. Latin America Vagus Nerve Stimulators Market, 2021-2031, USD (Million)
12.1. Market Overview
12.2. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
12.3. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
12.4. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
12.5. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
12.6.Vagus Nerve Stimulators Market: By Region, 2021-2031, USD (Million)
12.6.1.Latin America
12.6.1.1. Brazil
12.6.1.1.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
12.6.1.1.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
12.6.1.1.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
12.6.1.1.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
12.6.1.2. Mexico
12.6.1.2.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
12.6.1.2.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
12.6.1.2.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
12.6.1.2.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
12.6.1.3. Rest of Latin America
12.6.1.3.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
12.6.1.3.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
12.6.1.3.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
12.6.1.3.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
13. Middle East and Africa Vagus Nerve Stimulators Market, 2021-2031, USD (Million)
13.1. Market Overview
13.2. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
13.3. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
13.4. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
13.5. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
13.6.Vagus Nerve Stimulators Market: By Region, 2021-2031, USD (Million)
13.6.1.Middle East and Africa
13.6.1.1. GCC
13.6.1.1.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
13.6.1.1.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
13.6.1.1.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
13.6.1.1.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
13.6.1.2. Africa
13.6.1.2.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
13.6.1.2.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
13.6.1.2.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
13.6.1.2.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
13.6.1.3. Rest of Middle East and Africa
13.6.1.3.1. Vagus Nerve Stimulators Market: By Product, 2021-2031, USD (Million)
13.6.1.3.1. Vagus Nerve Stimulators Market: By Application, 2021-2031, USD (Million)
13.6.1.3.1. Vagus Nerve Stimulators Market: By Biomaterial, 2021-2031, USD (Million)
13.6.1.3.1. Vagus Nerve Stimulators Market: By End-use, 2021-2031, USD (Million)
14. Company Profile
14.1. electroCore
14.1.1. Company Overview
14.1.2. Financial Performance
14.1.3. Product Portfolio
14.1.4. Strategic Initiatives
14.2. Cerebral Rx
14.2.1. Company Overview
14.2.2. Financial Performance
14.2.3. Product Portfolio
14.2.4. Strategic Initiatives
14.3. MicroTransponder, Inc.
14.3.1. Company Overview
14.3.2. Financial Performance
14.3.3. Product Portfolio
14.3.4. Strategic Initiatives
14.4. Parasym
14.4.1. Company Overview
14.4.2. Financial Performance
14.4.3. Product Portfolio
14.4.4. Strategic Initiatives
14.5. LivaNova LLC (formerly Cyberonics)
14.5.1. Company Overview
14.5.2. Financial Performance
14.5.3. Product Portfolio
14.5.4. Strategic Initiatives
14.6. Other Notable Players
14.6.1. Company Overview
14.6.2. Financial Performance
14.6.3. Product Portfolio
14.6.4. Strategic Initiatives
List of Figures
Figure 1 Global Vagus Nerve Stimulators Market: Market Coverage
Figure. 2 Research Methodology and Data Sources
Figure. 3 Market Size Estimation - Top Down & Bottom-Up Approach
Figure. 4 Global Vagus Nerve Stimulators Market: Quality Assurance
Figure. 5 Global Vagus Nerve Stimulators Market, By Product, 2022
Figure. 6 Global Vagus Nerve Stimulators Market, By Application, 2022
Figure. 7 Global Vagus Nerve Stimulators Market, By Biomaterial, 2022
Figure. 8 Global Vagus Nerve Stimulators Market, By End-use, 2022
Figure. 9 Global Vagus Nerve Stimulators Market, By Geography, 2022
Figure. 10 Market Geographical Opportunity Matrix - Global Vagus Nerve Stimulators Market, 2022
Figure. 11 Market Positioning of Key Vagus Nerve Stimulators Market Players, 2022
Figure. 12 Global Vagus Nerve Stimulators Market - Tier Analysis - Percentage of Revenues by Tier Level, 2022 Versus 2031
Figure. 13 Global Vagus Nerve Stimulators Market, By Product, 2022 Vs 2031, %
Figure. 14 Global Vagus Nerve Stimulators Market, By Application, 2022 Vs 2031, %
Figure. 15 Global Vagus Nerve Stimulators Market, By Biomaterial, 2022 Vs 2031, %
Figure. 16 Global Vagus Nerve Stimulators Market, By End-use, 2022 Vs 2031, %
Figure. 17 U.S. Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 18 Canada Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 19 Rest of North America Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 20 UK Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 21 Germany Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 22 Spain Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 23 Italy Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 24 France Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 25 Rest of Europe Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 26 China Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 27 Japan Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 28 India Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 29 Australia Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 30 South Korea Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 31 Rest of Asia Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 32 Brazil Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 33 Mexico Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 34 Rest of Latin America Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 35 GCC Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 36 Africa Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
Figure. 37 Rest of Middle East and Africa Vagus Nerve Stimulators Market (US$ Million), 2021 - 2031
List of Tables
Table Global Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 2 Global Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 3 Global Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 4 Global Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 5 North America Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 6 North America Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 7 North America Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 8 North America Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 9 U.S. Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 10 U.S. Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 11 U.S. Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 12 U.S. Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 13 Canada Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 14 Canada Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 15 Canada Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 16 Canada Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 17 Rest of North America Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 18 Rest of North America Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 19 Rest of North America Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 20 Rest of North America Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 21 UK and European Union Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 22 UK and European Union Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 23 UK and European Union Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 24 UK and European Union Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 25 UK Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 26 UK Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 27 UK Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 28 UK Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 29 Germany Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 30 Germany Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 31 Germany Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 32 Germany Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 33 Spain Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 34 Spain Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 35 Spain Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 36 Spain Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 37 Italy Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 38 Italy Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 39 Italy Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 40 Italy Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 41 France Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 42 France Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 43 France Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 44 France Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 45 Rest of Europe Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 46 Rest of Europe Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 47 Rest of Europe Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 48 Rest of Europe Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 49 Asia Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 50 Asia Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 51 Asia Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 52 Asia Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 53 China Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 54 China Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 55 China Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 56 China Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 57 Japan Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 58 Japan Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 59 Japan Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 60 Japan Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 61 India Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 62 India Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 63 India Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 64 India Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 65 Australia Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 66 Australia Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 67 Australia Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 68 Australia Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 69 South Korea Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 70 South Korea Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 71 South Korea Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 72 South Korea Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 73 Latin America Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 74 Latin America Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 75 Latin America Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 76 Latin America Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 77 Brazil Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 78 Brazil Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 79 Brazil Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 80 Brazil Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 81 Mexico Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 82 Mexico Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 83 Mexico Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 84 Mexico Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 85 Rest of Latin America Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 86 Rest of Latin America Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 87 Rest of Latin America Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 88 Rest of Latin America Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 89 Middle East and Africa Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 90 Middle East and Africa Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 91 Middle East and Africa Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 92 Middle East and Africa Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 93 GCC Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 94 GCC Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 95 GCC Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 96 GCC Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 97 Africa Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 98 Africa Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 99 Africa Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 100 Africa Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)
Table 101 Rest of Middle East and Africa Vagus Nerve Stimulators Market By Product, 2021-2031, USD (Million)
Table 102 Rest of Middle East and Africa Vagus Nerve Stimulators Market By Application, 2021-2031, USD (Million)
Table 103 Rest of Middle East and Africa Vagus Nerve Stimulators Market By Biomaterial, 2021-2031, USD (Million)
Table 104 Rest of Middle East and Africa Vagus Nerve Stimulators Market By End-use, 2021-2031, USD (Million)

Companies Mentioned

  • electroCore
  • Cerebral Rx
  • MicroTransponder Inc.
  • Parasym
  • LivaNova LLC (formerly Cyberonics)