Report Scope:
The scope of the report includes DNA read, write and edit technologies, applications, industries, initiatives, patents, and companies. The markets for read, write and edit products and services are given for 2017, 2018, 2019 (estimated) and 2024 (forecast).
This report reviews the main read, write and edit technologies and explains why genetic variation is important in clinical testing and disease. It then discusses significant large-scale research initiatives that impact read, write and edit applications. Of particular interest is a discussion of population-scale sequencing projects throughout the world, and their likely impact. The main market driving forces for read, write and edit products and services are listed and discussed.
The report quantifies each of the main market segments. The read (sequencing) market is quantified by delivered format, including sequencing workflow products (sample preparation kits and reagents, sequencing instruments and consumables, and informatics) and sequencing services (clinical diagnostics and sequencing services to applied market customers).
The sequencing workflow products market is quantified by type, that is, DNA isolation and extraction; target enrichment; library preparation; and informatics/ecosystems. The sequencing instruments and consumables market is given by platform (Sanger, NGS, and 3GS).
The sequencing services market is analyzed by end-user application (applied, clinical, and R&D). Within sequencing services, the applied market is analyzed by end-user application (agriculture, biopharma, consumer, microbiology, population-scale genomics, synthetic biology and other).
Also within sequencing services, the clinical market is analyzed and quantified by disease category (cardiovascular, clinical microbiology and infectious diseases, Mendelian disorders, metabolic/immune disorders, neurology, oncology, reproductive health, and transplant medicine).
The DNA write (synthesis) market is quantified by product type (oligonucleotides, synthetic biology parts, genes, and RNA therapeutics). The oligonucleotide market is analyzed by application (gene editing, sequencing, PCR, FISH, microarray, gene synthesis and other). The gene market is quantified by gene type (standardized, value-added). Finally, the RNA therapeutics market is quantified by platform (RNA interference, antisense oligos, micro RNA modulation, and mRNA) and by disease category (cancer, hematology, musculoskeletal, neurology, and rare diseases).
The DNA edit (gene editing) market is quantified by application (agriculture, biopharma, diagnostics, and therapeutics); editing platform (CRISPR, meganuclease, TALEN, ZFN). The gene-editing agriculture market is analyzed by product type (crop/seeds, livestock). The gene-editing biotechnology market is analyzed by product type (kits and reagents, cell line engineering, animal models and services). The gene-editing therapeutics market is analyzed by disease category (eye and rare diseases).
Specific geographic markets discussed include North America, Europe, Asia-Pacific, and the rest of the world (ROW).
Industry sectors analyzed include next-generation sequencing; long-read sequencing; DNA synthesis; RNA therapies; and gene editing.
More than 320 companies in the read, write and edit industry are profiled in this report.
The author also provides a summary of more than 180 of the main industry acquisitions and strategic alliances that took place from January 2018 through June 2019, including key alliance trends.
Report Includes:
- 28 data tables and 77 additional tables
- An overview of the global market for DNA read, write and edit technologies, applications, and industries
- Analyses of global market trends, with market data from 2017, 2018, estimates for 2019, and projections of compound annual growth rates (CAGRs) through 2024
- Discussion on sequencing technologies, market applications, industry structure, and important clinical sequencing initiatives
- Information pertaining to several significant large-scale research initiatives that are contributing to sequencing services write synthesis and gene editing technologies’ market development
- A look at the innovations in pharmaceutical and biotechnology companies and research & development programs in stem cell-based therapies and gene therapies
- Coverage of significant patents and their allotments in each category, as well as major industry acquisitions and strategic alliances data
- Company profiles of over 320 major global players within the industry, including 3Billion Inc., 23Andme Inc., Bayer AG, Becton, Dickinson and Co. (BD), Bio-Rad Laboratories, Pacific Biosciences, Qiagen NV, Roche Holding AG, and Thermo Fisher Scientific Inc.
Table of Contents
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Executive Summary
DNA (and RNA) read, write and editing includes the primary methods in which nucleic acids are analyzed (sequencing), created (synthesis) and modified (gene editing). It is becoming increasingly important in the life sciences industry to be expert in all aspects of nucleic acids in order to exploit significant opportunities within this industry. The end-users for these technologies include any industry that works with biological systems, and even some that don’t (e.g., DNA data storage).
The DNA read, write and edit industry is at the beginning stages of its growth story; penetration of the key markets is still at an early stage. The data indicates that there is a significant future upside for sequencing across research, metagenomics, agriculture, synthetic biology, and clinical applications, among others.
The situation is similar for DNA writing and editing technologies, with clinical therapeutic applications, in particular, providing an enormous total available future market that is yet to be significantly penetrated. Major successes in this industry include the adoption of next-generation sequencing (NGS) for noninvasive prenatal testing; enabling the roles of synthetic DNA oligonucleotides and genes in the rise of the synthetic biology industry; and rapid adoption of CRISPR gene editing by research institutions and biopharma industries.
There is increasing interplay among the three DNA technology platforms, giving rise to innovative corporate strategies. For example, Arbor Biotechnologies employs sequencing, gene synthesis, and artificial intelligence to perform high-throughput discovery of biomolecules, including new CRISPR proteins.
Companies Mentioned
- 10X Genomics Inc.
- 23andMe Inc.
- 3Billion Inc.
- Adaptive Biotechnologies Inc.
- Admera Health
- Adverum Biotechnologies
- Agilent Technologies Inc.
- Ajinomoto Co., Inc.
- Alcediag
- Aldevron
- Allergan Plc
- Allogene Therapeutics Inc.
- Almac Group Ltd.
- Amarantus Bioscience Holdings Inc.
- Ambry Genetics
- Amfora Inc.
- Anchordx Medical Co., Ltd.
- Anges Inc.
- Annoroad Gene Technology Co., Ltd.
- Ansa Biotechnologies Inc.
- Apeiron Biologics AG
- Aperiomics Inc.
- Arbor Biotechnologies Inc.
- Arcadia Biosciences Inc.
- Archer Dx
- Arcturus Therapeutics Inc.
- Arup Laboratories
- Asia Genomics Pte. Ltd.
- Astrazeneca Plc
- Astridbio Technologies Kft.
- Asuragen Inc.
- Atg Biosynthetics GmbH
- Athena Diagnostics Inc.
- Atreca Inc.
- Atum
- Avecia
- B-Mogen Biotechnologies Inc.
- Base4 Innovation Ltd.
- Basf AG
- Bayer AG
- Baylor Genetics
- Beam Therapeutics Inc.
- Becton, Dickinson And Co.
- Benson Hill Biosystems Inc.
- Berry Genomics Co., Ltd.
- Bgi Shenzhen
- Bio Basic Inc.
- Bio S&T Inc.
- Bio-Rad Laboratories Inc.
- Bio-Techne Ltd.
- Bioarray S.L.
- Biocept Inc.
- Biodesix Inc.
- Biogen Inc.
- Biomarx Inc.
- Bioneer Corp.
- Blue Heron Biotech Llc
- Bluebird Bio
- Blueprint Genetics
- Bluestar Genomics Inc.
- Boreal Genomics
- Bristol-Myers Squibb Co.
- Brooks Life Sciences
- Calyxt Inc.
- Cambridge Epigenetix Ltd.
- Cancer Genetics
- Caredx Inc.
- Caribou Biosciences Inc.
- Caris Life Sciences
- Casebia Therapeutics
- Caszyme
- Catalog Technologies Inc.
- Cegat GmbH
- Celgene Corp.
- Cellectis SA
- Cellmax Life
- Celsee Inc.
- Centogene AG
- Cergentis B.V.
- Chronix Biomedical
- Cibus Inc.
- Circulogene Theranostics
- Circulomics Inc.
- Cofactor Genomics Inc.
- Color Genomics
- Coopersurgical, Inc.
- Coriell Life Sciences Inc.
- Cosmosid
- Crispr Therapeutics AG
- Cygnus Biosciences Co., Ltd.
- Danaher Corp.
- Darui Biotechnology Co., Ltd.
- Datar Cancer Genetics Ltd.
- Depixus
- Desktop Genetics Ltd.
- Devyser Ab
- Diacarta Inc.
- Diagnomics
- Diploid
- Direct Genomics Co., Ltd.
- Directed Genomics Llc
- DNA Electronics Ltd.
- DNA Script
- Dnanexus Inc.
- Dovetail Genomics Llc
- Dowdupont Inc.
- Edigene Corp.
- Edigene Inc.
- Editas Medicine Inc.
- Egenesis Inc.
- Electronic Biosciences
- Eligo Bioscience
- Envision Genomics
- Epic Sciences Inc.
- Epoch Life Science Inc.
- Esperite Nv
- Etagen Pharma
- Eurofins Scientific
- Evonetix
- Exact Sciences Corp.
- Expedeon AG
- Ezlife Bio Inc.
- Fabric Genomics
- Fluxion Biosciences Inc.
- Freenome Inc.
- Fry Laboratories Llc
- Full Genomes Corp.
- Fusion Genomics Corp.
- G+Flas Life Sciences Inc.
- Genapsys Inc.
- Gencove Inc.
- Gendx Bv
- Gene By Gene Ltd.
- Genedx Inc.
- Genemed Synthesis Inc.
- Generay Biotech Co., Ltd.
- Genetics Research Llc
- Genexosome Technologies Inc.
- Genomatix Software GmbH
- Genome Profiling Llc
- Genome. One Pty Ltd.
- Genomic Expression
- Genomic Health Inc.
- Genomnia Srl
- Genomoncology
- Genoox
- Genospace
- Genscript
- Genus Plc
- Gigagen Inc.
- Gilead Sciences Inc.
- Ginkgo Bioworks
- Golden Helix
- Grail Inc.
- Grandomics Biosciences Co., Ltd.
- Guardant Health Inc.
- Guardiome
- Haplox Biotechnology
- Helitec
- Helix Opco Llc
- Helixworks Technologies Ltd.
- Histogenetics Llc.
- Homology Medicines Inc.
- Horizon Discovery Group Plc
- Htg Molecular Diagnostics Inc.
- Human Longevity Inc.
- Illumina Inc.
- Inex Innovations Exchange Pte. Ltd.
- Inivata Ltd.
- Inscripta Inc.
- Intellia Therapeutics Inc.
- Interpace Diagnostics Llc
- Invitae
- Invivoscribe Inc.
- Irepertoire Inc.
- Kailos Genetics
- Kaneka Eurogentec S.A.
- Karius Inc.
- Kellbenx Inc.
- Kew Inc.
- Kingmed Diagnostics Center Co., Ltd.
- KWS Saat Se
- Labgenius Ltd.
- Laboratory Corp. Of America Inc.
- Laboratory For Molecular Medicine
- LC Sciences
- Leucine Rich Bio Pvt. Ltd.
- Lexent Bio Inc.
- LGC Group
- Locus Biosciences
- Logicbio Therapeutics
- Loop Genomics
- Lunglife Ai, Inc.
- Macrogen Inc.
- Mapmygenome
- Mayo Medical Laboratories
- Mdxhealth Inc.
- Medgenome Labs Pvt. Ltd.
- Menarini Silicon Biosystems Spa
- Merck Kgaa
- Microsoft Corp.
- Mogene Llc
- Molecular Assemblies Inc.
- Molecular Health GmbH
- Molecular Loop Biosolutions Llc
- Molecularmd Corp.
- Myriad Genetics, Inc.
- N-Of-One Inc.
- Nanostring Technologies Inc.
- Natera Inc.
- Naveris Inc.
- Neogenomics Laboratories
- New England Biolabs
- New Oncology GmbH
- Newgene Ltd.
- Ngenebio Co., Ltd.
- Nipd Genetics
- Novartis Pharma AG
- Novogene Co., Ltd.
- Nucelis Llc
- Nuclera Nucleics Ltd.
- Nugen Technologies Inc.
- Numedii
- Nuprobe Inc.
- NX Prenatal Inc.
- Ocunexus Therapeutics Inc.
- Omega Bio-Tek Inc.
- Omniseq Llc
- Oncocyte Corp.
- Oncodna S.A.
- Oneome Inc.
- Ontera
- Othram Inc.
- Oxford Biomedica Plc
- Oxford Genetics Ltd.
- Oxford Nanopore Technologies Ltd.
- Pacific Biosciences Of California, Inc.
- Pairwise Plants Inc.
- Pangaea Oncology
- Paradigm Diagnostics Inc.
- Parseq Lab Co., Ltd.
- Pathway Genomics Corp.
- Perkinelmer Inc.
- Personal Genome Diagnostics Inc.
- Personalis Inc.
- Pfizer Inc.
- Phio Pharmaceuticals Corp.
- Pieriandx
- Population Genetics Technologies Ltd.
- Portable Genomics Llc
- Poseida Therapeutics Inc.
- Positive Bioscience
- Precipio Inc.
- Precision Biosciences Inc.
- Predicine Inc.
- Prenetics
- Preventiongenetics Inc.
- Promega Corp.
- Q-State Biosciences
- Qiagen Nv
- Quantapore Inc.
- Quantum Biosystems Inc.
- Quantumdx
- Quest Diagnostics Inc.
- Rarecyte Inc.
- Real-Time Genomics Inc.
- Recombinetics, Inc.
- Resolution Bioscience Inc.
- Roche Holding AG
- Sangamo Therapeutics Inc.
- Sarepta Therapeutics Inc.
- Screencell
- Seekin
- Sequencing.Com
- Seven Bridges Genomics Inc.
- Sgi-Dna Inc.
- Sherlock Biosciences
- Shinegene Molecular Bio-Technologies Inc.
- Sigma Aldrich Corp.
- Singlera Genomics Inc.
- Sistemas Genómicos Sl
- Softgenetics Llc
- Sophia Genetics
- Spera Medical
- Sta Pharmaceutical Co., Ltd.
- Strand Life Sciences Pvt. Ltd.
- Stratos Genomics Inc.
- Supratech Micropath Laboratory & Research Institute Pvt. Ltd.
- Syapse
- Synbio Technologies Inc.
- Syngenta AG
- Synpromics Ltd.
- Synthego Corp.
- Synthetic Genomics Inc.
- Takara Bio
- Tempus
- Theranosis Life Sciences Pvt. Ltd.
- Thermo Fisher Scientific Inc.
- Thrive Early Detection Corp.
- Toolgen
- Trace Genomics Inc.
- Translate Bio
- Tropic Biosciences Uk Ltd.
- Twinstrand Biosciences
- Twist Bioscience
- Ubiquity Genomics Inc.
- Vela Diagnostics
- Veritas Genetics
- Verogen Inc.
- Vir Biotechnology Inc.
- Vortex Biosciences
- Xing Technologies Llc
- Yield10 Biosciences Inc.
- Yikon Genomics Co., Ltd.
- Yourgene Health Plc
- Zhejiang Dian Diagnostics Co., Ltd.