+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)

American Academy of Neurology (AAN) Annual Meeting, 2019 Assessment Report

  • PDF Icon

    Report

  • 72 Pages
  • May 2019
  • Region: United States
  • Citeline
  • ID: 4846141
Overview

The 71st Annual Meeting of the American Academy of Neurology (AAN) was held in Philadelphia, Pennsylvania, from May 4-10, 2019.

Conference highlights included movement in the rare disease space, namely pertaining to updated data in spinal muscular atrophy, early-phase data in amyotrophic lateral sclerosis, and pivotal data in neuromyelitis optica spectrum disorder. These were particularly noteworthy considering the lack of therapy options for these severe indications and the associated critical unmet need.

This post-meeting report features summaries of key topics alongside commentary from our team of expert analysts. It also includes a compilation of all data events added in conjunction with the meeting.

Table of Contents

Meeting Overview – Key IndicationsAmyotrophic Lateral Sclerosis (ALS)
Migraine
  • Acute Migraine
  • Chronic and Episodic Migraine
  • Neuromyelitis Optica Spectrum Disorder (NMOSD)
  • Spinal Muscular Atrophy (SMA)

Selected Abstracts Featured at AAN
Amyotrophic Lateral Sclerosis (ALS)
  • IONIS-SOD1Rx (BIIB, III)
  • CK-2127107 (CYTK, Phase II)

Essential Tremor
  • CX-8998 (Cavion, Phase II)

Migraine and Other Headaches
  • Eptinezumab (ALDR, BLA)
  • Eptinezumab (ALDR, BLA)
  • Atogepant (AGN, III)
  • Ubrogepant (AGN, NDA)
  • Rimegepant (BHVN, III)
  • Emgality (LLY, Approved)
  • Emgality (LLY, Approved)

Myasthenia Gravis (MG)
  • Zilucoplan (RARX, II)

Neuromyelitis Optica (Devic’s syndrome, NMO)
  • Soliris (ALXN, BLA)
  • Satralizumab (RHHBY, III)
  • Inebilizumab (Viela, III)

Parkinson's Disease (PD)
  • DynaCirc (GSK, Investigator Initiated)
  • Ongentys (NBIX, Phase III)
  • VY-AADC (VYGR, Phase II)

Seizure Disorders (Epilepsy)
  • Valtoco (Neurelis, NDA)

Spinal Muscular Atrophy
  • Spinraza (BIIB, Approved)
  • Spinraza (BIIB, Approved)
  • Spinraza (BIIB, Approved)
  • Zolgensma (NVS, BLA)
  • Zolgensma (NVS, BLA)
  • Zolgensma (NVS, BLA)
  • Zolgensma (NVS, BLA)
  • Risdiplam (RHHBY, III)

List of Biomedtracker AAN Events