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Recent Advances in Parkinson's Disease, Vol 252. Progress in Brain Research

  • ID: 4850280
  • Book
  • April 2020
  • Region: Global
  • 358 Pages
  • Elsevier Science and Technology
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Recent Advances in Parkinson´s Disease Research, Volume 252, represents a follow-up on two previous volumes presented in the Progress in Brain Research series, Volumes 193 and 193, both published in 2010. It contains a collection of overview articles written by leading researchers in Parkinson's, discussing the most important advances made in basic, translational and clinical research. Topics of note in this new release include What can we learn from iPS cell models of PD, What can we learn from animal models of PD?, Molecular basis of selective neuronal vulnerability in PD, Role of innate and adaptive immunity in Parkinson´s disease, and much more.

  • Covers all key aspects of current research on Parkinson´s disease
  • Includes topics that range from basic studies on disease models and pathogenic pathways (e.g., protein misfolding, immune and glial mechanisms) to clinical studies on disease features, microbiome, pathophysiology and therapeutic approaches
  • Presents articles authored by world leaders in their respective fields
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What we can learn from iPSC-derived cellular models of Parkinson's disease?

Maria Claudia Caiazza, Charmaine Lang and Richard Wade-Martins

2. Animal models for preclinical Parkinson's research: An update and critical appraisal

M. Angela Cenci and Anders Björklund

3. Selective neuronal vulnerability in Parkinson's disease

Patricia Gonzalez-Rodriguez, Enrico Zampese and D. James Surmeier

4. Mechanisms of alpha-synuclein toxicity: An update and outlook

Inês Caldeira Brás, Mary Xylaki and Tiago Fleming Outeiro

5. The role of glia in Parkinson's disease: Emerging concepts and therapeutic applications

Katarzyna Z. Kuter, M. Angela Cenci and Anna R. Carta

6. Innate and adaptive immune responses in Parkinson's disease

Aubrey M. Schonhoff, Gregory P. Williams, Zachary D. Wallen, David G. Standaert and Ashley S. Harms

7. Pathways of protein synthesis and degradation in PD pathogenesis

Rebekah G. Langston and Mark R. Cookson

8. Endosomal sorting pathways in the pathogenesis of Parkinson's disease

Lindsey A. Cunningham and Darren J. Moore

9. New players in basal ganglia dysfunction in Parkinson's disease

Sara Meoni, Rubens Gisbert Cury and Elena Moro

10. Prodromal PD: A new nosological entity

Eva Schaeffer, Ronald B. Postuma and Daniela Berg

11. The gut microbiome in Parkinson's disease: A culprit or a bystander?

Ali Keshavarzian, Phillip Engen, Salvatore Bonvegna and Roberto Cilia

12. Novel approaches to counter protein aggregation pathology in Parkinson's disease

Simon R.W. Stott, Richard K. Wyse and Patrik Brundin

13. Repurposing anti-diabetic drugs for the treatment of Parkinson's disease: Rationale and clinical experience

Tom Foltynie and Dilan Athauda

14. Basal ganglia oscillations as biomarkers for targeting circuit dysfunction in Parkinson's disease

Per Petersson, Andre
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