The global Neutropenia treatment market was valued at USD 11,279.2 Mn in 2018, and is expected to reach USD 17,331.4 Mn by 2027, expanding at a CAGR of 5.0% from 2019 to 2027.
Market Insights:
Neutropenia is a rare disease in which sudden decrease in neutrophil level is observed leading to compromised immunity. Neutropenia may be caused due to several diseases or conditions such as cancer chemotherapy, infections, congenital bone marrow disorders, autoimmune disorders, and specific medicines (drug-induced neutropenia). According to experts, when the level of neutrophils is less than 1,500 neutrophils per microliter of blood in adult neutropenia is confirmed, but in some cases the level of neutrophils can be lower-than-average but do not have risk of infection. The global prevalence of acute neutropenia lies between 0.9% & 2.0% and the prevalence of chronic neutropenia in a range of 0.06% to 0.12%. The key factors responsible for the growth of neutropenia treatment market such as the increasing prevalence of leukemia, chemotherapy is first the line of action against leukemia, and high awareness related to neutropenia in physicians.
In 2018, Granulocyte-colony stimulating factor (G-CSF) drug class dominated the overall neutropenia treatment market being the first-line of action and only target-specific drug approved by regulatory bodies. G-CSF stimulates the production of granulocytes in patients suffering with neutropenia leading to an increase in the count of white blood cells. In cancer patients, G-CSF is prescribed as primary prophylaxis which refers to its application post the first cycle of chemotherapy in cancer patients but before the development of neutropenia to prevent further complications. The overall pipeline of neutropenia treatment seems promising with products present in phase III of clinical trials such as SPI-2012 (Spectrum Pharmaceuticals, Inc.), F-627 (Generon (Shanghai) Corporation Ltd.), Leucostim (Dong-A ST Co., Ltd.) and Plinabulin (BeyondSpring Pharmaceuticals Inc.) among others.
During the forecast period from 2019 to 2027, Asia Pacific was identified as the fastest growing region in neutropenia treatment due to the rising prevalence of leukemia in Asia Pacific, increasing awareness related to neutropenia diagnostics & treatment, and evolving accessibility for novel drugs entering in the market by 2027.
Market Competition Assessment:
The neutropenia treatment market will significantly grow and key companies operating in this market are promoting research & development activities as well as awareness related to neutropenia treatment. The key market strategies used by companies present in this market are increasing awareness related to prophylactic measures, early diagnosis, and effective treatment of neutropenia. The companies present in this market are Amgen, Inc., Spectrum Pharmaceuticals, Inc., Generon (Shanghai) Corporation Ltd., Dong-A ST Co., Ltd., BeyondSpring Pharmaceuticals Inc., Myelo Therapeutics, Inc., Cellerant Therapeutics, Inc., and Sandoz (Subsidary of Novartis AG) among others.
Key Market Movements:
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Market Insights:
Neutropenia is a rare disease in which sudden decrease in neutrophil level is observed leading to compromised immunity. Neutropenia may be caused due to several diseases or conditions such as cancer chemotherapy, infections, congenital bone marrow disorders, autoimmune disorders, and specific medicines (drug-induced neutropenia). According to experts, when the level of neutrophils is less than 1,500 neutrophils per microliter of blood in adult neutropenia is confirmed, but in some cases the level of neutrophils can be lower-than-average but do not have risk of infection. The global prevalence of acute neutropenia lies between 0.9% & 2.0% and the prevalence of chronic neutropenia in a range of 0.06% to 0.12%. The key factors responsible for the growth of neutropenia treatment market such as the increasing prevalence of leukemia, chemotherapy is first the line of action against leukemia, and high awareness related to neutropenia in physicians.
In 2018, Granulocyte-colony stimulating factor (G-CSF) drug class dominated the overall neutropenia treatment market being the first-line of action and only target-specific drug approved by regulatory bodies. G-CSF stimulates the production of granulocytes in patients suffering with neutropenia leading to an increase in the count of white blood cells. In cancer patients, G-CSF is prescribed as primary prophylaxis which refers to its application post the first cycle of chemotherapy in cancer patients but before the development of neutropenia to prevent further complications. The overall pipeline of neutropenia treatment seems promising with products present in phase III of clinical trials such as SPI-2012 (Spectrum Pharmaceuticals, Inc.), F-627 (Generon (Shanghai) Corporation Ltd.), Leucostim (Dong-A ST Co., Ltd.) and Plinabulin (BeyondSpring Pharmaceuticals Inc.) among others.
During the forecast period from 2019 to 2027, Asia Pacific was identified as the fastest growing region in neutropenia treatment due to the rising prevalence of leukemia in Asia Pacific, increasing awareness related to neutropenia diagnostics & treatment, and evolving accessibility for novel drugs entering in the market by 2027.
Market Competition Assessment:
The neutropenia treatment market will significantly grow and key companies operating in this market are promoting research & development activities as well as awareness related to neutropenia treatment. The key market strategies used by companies present in this market are increasing awareness related to prophylactic measures, early diagnosis, and effective treatment of neutropenia. The companies present in this market are Amgen, Inc., Spectrum Pharmaceuticals, Inc., Generon (Shanghai) Corporation Ltd., Dong-A ST Co., Ltd., BeyondSpring Pharmaceuticals Inc., Myelo Therapeutics, Inc., Cellerant Therapeutics, Inc., and Sandoz (Subsidary of Novartis AG) among others.
Key Market Movements:
- Rising awareness specific to neutropenia & chemotherapy-related side-effects and developing diagnostic technology is anticipated to assist the overall growth of neutropenia treatment in the near future
- Promising drug pipeline with around 5 drugs in phase III clinical trials to treat neutropenia is responsible for significant growth
- Increasing prevalence of leukemia is expected to rise the risk of neutropenia especially post chemotherapy
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Table of Contents
Chapter 1. Preface
Chapter 2. Executive Summary
Chapter 3. Global Neutropenia Treatment Market: Market Dynamics and Future Outlook
Chapter 4. Global Neutropenia Treatment Market, by Type of Drug Class, 2017 – 2027 (US$ Mn)
Chapter 5. Global Neutropenia Treatment Market, Pipeline Analysis
Chapter 6. Global Neutropenia Treatment Market, by Geography, 2017 – 2027 (US$ Mn)
Chapter 7. Company Profiles
Companies Mentioned
- Amgen, Inc.
- Pfizer, Inc.
- Myelo Therapeutics, Inc.
- Cellerant Therapeutics, Inc.
- Sandoz (Subsidary of Novartis AG)
- BeyondSpring Pharmaceuticals Inc.
- Enzychem Lifesciences Corporation
- Spectrum Pharmaceuticals, Inc.
- Tianjin SinoBiotech Ltd.
- S&D Pharma SK s.r.o.
- Samsung Medical Center
- Generon (Shanghai) Corporation Ltd.
- PhytoHealth Corporation
- Dong-A ST Co., Ltd.
