Stem cells are primitive cells found in all multi-cellular organisms that are characterized by self-renewal and the capacity to differentiate into mature cell types.
Several broad categories of stem cells exist, including:
- Embryonic stem cells, derived from blastocysts
- Perinatal stem cells, obtained during the period immediately before and after birth
- Adult stem cells, found in adult tissues
- Induced pluripotent stem cells, produced by genetically reprogramming adults cells
- Cancer stem cells, which give rise to clonal populations of cells that form tumors or disperse in the body
Stem cell research and experimentation have been in process for well over five decades, as stem cells have the unique ability to divide and replicate repeatedly. In addition, their “unspecialized” nature allows them to differentiate into a wide variety of specialized cell types. In a developing embryo, stem cells can differentiate into all of the specialized embryonic tissues. In adult organisms, stem and progenitor cells act as a repair system for the body, replenishing specialized cells.
The possibilities arising from these characteristics have resulted in great commercial interest, with potential applications ranging from the use of stem cells in reversal and treatment of disease, to cell therapy, tissue regeneration, bioprinting, drug discovery, toxicology testing, and more. Of interest to clinical researchers is the potential to use stem cells within regenerative medicine, and the pharmaceutical industry is integrating stem cells to conduct pharmacological testing on cell-specific tissues. There is also demand for extracellular vesicles (EVs) derived from stem cells, because they can act as intercellular messengers and may be able to exert some types of therapeutic effects.
Traditionally, scientists have worked with both embryonic and adult stem cells as research tools. While the appeal of embryonic cells has been their ability to differentiate into any type of cell, there has been significant ethical, moral, and spiritual controversy surrounding their use for research purposes. Although some adult stem cells do have differentiation capacity, it is often limited in nature, which results in fewer options for use. Thus, when induced pluripotent stem cells (iPSCs) were discovered in 2006 by Shinya Yamanaka of Kyoto University in Japan, they represented a promising combination of adult and embryonic stem cell characteristics.
iPSCs are adult cells which are isolated and then transformed into embryonic-like stem cells through the manipulation of gene expression and other methods. The first successful generation of iPSCs was via research and experimentation using mouse cells at Kyoto University in Japan. In 2007, a series of follow-up experiments were done at Kyoto University in which human adult cells were transformed into iPSC cells. Nearly simultaneously, a research group led by James Thomson at the University of Wisconsin-Madison accomplished the same feat of deriving iPSC lines from human somatic cells.
To facilitate research resulting from interest in these far-ranging applications, a large and rapidly growing market for stem cells research products has emerged. Today, well over one-hundred companies produce products to support the activities of stem cell scientists worldwide. The tools commercialized by these companies include ones to isolate, expand, culture, differentiate, and characterize stem cells, as well as technologies to enable their production at any scale.
Broad categories of stem cell research products include, but are not limited to:
- Stem cell lines (such as iPSCs, MSCs, HSCs, NSCs, and ESCs)
- Stem cell culture media with supplements
- Consumables (such as antibodies, consumables in assays, cryoprotective agents and microcarriers)
- Instruments (such as freezers, bioreactors, cytometry devices, and assay systems)
- Stem cell services
Specifically, the following compose the majority of stem cell product sales:
- Primary antibodies to stem cell antigens
- Bead-based stem cell separation systems
- Fluorescent-based labeling and detection
- Stem cell protein purification and analysis tools
- Tools for DNA and RNA-based characterization of stem cells
- Isolation/characterization services
- Stem cell culture media and reagents
- Stem cell-specific growth factors and cytokines
- Tools for stem cell gene regulation
- Mechanisms for in vivo and in vitro stem cell tracking
- Expansion/differentiation services for stem cell media and RNAi
- Stem cell lines
- Done-for-you or done-with-you services
With market competition growing increasingly fierce, ten of the largest companies selling stem cell research products are:
- Thermo Fisher Scientific
- BD Biosciences, a Division of Becton Dickinson (BD)
- Merck KGaA
- Miltenyi Biotec
- STEMCELL Technologies
- Lonza Group
- Takara Bio
- GE Healthcare Life Sciences
- FUJIFILM CDI
- Sigma Aldrich
Furthermore, there are many speciality vendors of stem cell research products, such as FUJIFILM CDI, ReproCELL and Ncardia (who specialize in iPSC-related products), RoosterBio (who specializes in human MSC-specific products), and Corning (who specializes in Matrigel® products to support pluripotent stem cell culture and cultureware), for example.
Key report findings include:
- Stem cell research applications, including priorities by segment
- The relative demand for stem cell products, by stem cell type
- Analysis of stem cell manufacturing technologies, including costs, risks, and the rise of contract manufacturing organizations (CMOs)
- Analysis of market trends, including opportunities and threats
- Competitive analysis for 128 market participants composing the global market
- Market size determination, including detailed segmentation and 5-year projections (2019-2024)
The content and statistics contained in this report were compiled using a broad range of sources. These input sources include:
- Interviews with Stem Cell Executives, completed by the publisher's Founder and Analysts
- Stem Cell Grant Funding Database (Report Database, CIRM, MRC, Wellcome Trust - UK)
- Stem Cell Patent Database (United States Patent and Trade Office, World Intellectual Property Organization)
- Stem Cell Clinical Trial Database (ClinicalTrials.gov, International Clinical Trials Registry Platform, European Union Clinical Trials Register)
- Stem Cell Scientific Publication Database (PubMed, Highwire Press, Google Scholar)
- Stem Cell Product Launch Announcements (Trade Journals, Google News)
- Stem Cell Industry Events (Google News, Google Alerts)
- Stem Cell Company News (SEC Filings, Investor Publications, Historic Performance)
- Social Analytics Platforms (Google Trends, Google Adwords, BuzzSumo, Hashtagify.me)
The possibilities arising from stem cells have resulted in great commercial interest. The purpose of this report is to reveal market dynamics affecting basic and translational research, clinical and commercial applications, and the rising demand for stem cell research products on a global basis. Importantly, it unveils the identities of leading market competitors and presents a market size breakdown, including detailed segmentation with 5-year projections. Use it to identify emerging market opportunities, spot new product development opportunities before your competition, and make smarter decisions, faster.
1. REPORT OVERVIEW
1.1 Statement of the Report
1.2 Executive Summary
2. STEM CELL RESEARCH: AN INTRODUCTION
2.1 Identification of Stem Cells
2.2 Species Sources of Stem Cells for Research
2.3 Culturing Stem Cell Lines
2.4 Differentiation of Stem Cells
2.5 Benefits of Stem Cell Research
2.5.1 Basic Research
2.5.2 Stem Cells in Drug Discovery
2.5.3 Disease Modeling
2.5.4 Stem Cells in Toxicity Screening
3. STEM CELLS MARKERS
3.1 Embryonic Stem Cell (ESC) Markers
3.2 Hematopoietic Stem Cell Markers
3.3 Cancer Stem Cell Markers
3.4 Osteoprogenitor Cell Markers
3.5 Neural Stem Cell Markers
3.6 Mesenchymal Stem Cell Markers
3.7 Skin Stem Cell Markers
4. STEM CELL ISOLATION PRODUCTS
4.1 Flow Cytometry in Stem Cell Isolation
4.2 Flow Cyometry Systems
5.1 Primary Antibodies
5.2 Secondary Antibodies
5.3 Recombinant Antibodies
5.4 Trial Size Antibodies
5.5 Apoptosis Antibodies
5.6 Epitope Tag and Fusion Protein Antibodies
5.7 Isotype CONTrol Antibodies
5.8 Stem Cell Marker Antibodies
5.9 Pluripotent Stem Cell Markers Antibody Products
5.10 Mesenchymal Stem Cell Markers Antibody Products
5.11 Hematopoietic Stem Cell Markers Antibody Products
5.12 Neural Stem Cell Marker Antibodies
5.13 Cancer Stem Cell Marker Antibodies
5.14 Antibody Production
5.14.1 Antibody Production and Development Services
5.14.2 Monoclonal Antibody Production Services
5.14.3 Polyclonal Antibody Production Services
5.14.4 Antibody Purification Services
5.14.5 Antibody Conjugation and Labeling Services
5.14.6 Hybridoma Services
5.14.7 Recombinant Antibody Production Services
5.15 Stem Cell Factor ELISA Kits
6. STEM CELL CULTURE MEDIA
6.1 Types of Culture Media
6.2 Choice of Cell Culture Media
6.2.1 Recommended Media for Primary Cell Culture
6.3 Stem Cell Culture Media
6.3.1 Methylcellulose Media
6.3.2 Differentiation Media
6.3.3 Expansion Media
6.4 Embryonic Stem Cell Media
6.5 Hematopoietic Stem Cell Media
6.6 Mesenchymal Stem Cell Media
6.7 Neural Stem Cell Media
6.8 Media Supplements for Stem Cell Culture
6.9 Cell Storage Media
7.1 Stainless Steel Fixed Bioreactors
7.2 Single-Use Bioreactors
7.2.1 Single-Use System Types
7.2.2 Main Features of Commercial Bioreactors
7.2.3 Main Differences between Single-Use and Multi-Use Bioreactors
7.2.4 Microcarriers used in Bioreactors
8. STEM CELL LINES
8.1 Use of Stem Cell Lines
8.2 Types of Stem Cell Lines
8.2.1 Embryonic Stem Cell Lines (ESC Line)
8.2.2 Adult Stem Cell Lines
8.2.3 Induced Pluripotent Stem Cell Lines (iPSC Lines)
8.3 Commercially Available Stem Cell Lines
9. STEM CELL MANUFACTURING
9.1 Institutional Manufacturing of Stem Cells
9.2 Transition to Commercial Manufacturing of Stem Cells
9.3 CMOs Involved with Stem Cell Manufacturing
9.4 Stem Cell Manufacturing Process
9.4.1 Scale-Up Methods
9.4.2 Closed Automated Systems
10. COST OF STEM CELL MANUFACTURING
10.1 Labor Cost in Manufacturing Stem Cells
10.2 Cost of Stem Cell Manufacture in a Partially-Automated Facility
10.3 Cost of Stem Cell Manufacture in a Fully-Automatic Facility
11. STEM CELL RESEARCH PRODUCTS: MARKET ANALYSIS
11.1 Global Market for Flow Cytometry Systems used in Cell Culture Studies
11.1.1 Flow Cytometry Market Share by Company
11.2 Global Market for Stem Cell Research Antibodies
11.2.1 Stem Cell Research Antibodies Market Share by Company
11.3 Market for Stem Cell Assay Products
11.3.1 Global Market for Stem Cell Assays by Product Segments
11.4 Global Market for Stem Cell Culture Media
11.4.1 Stem Cell Culture Media Market Share by Company
11.5 Global Market for Recombinant Cell Culture Supplements
11.6 Global Market for Stem Cell Cryopreservation Products
11.6.1 Market Share of Cryopreservation Products by Type
11.7 Market for Single-Use Bioreactors in Stem Cell Culture
11.7.1 Market for Single-Use Bioreactors in Stem Cell Culture by Product Segment
11.7.2 Single-Use Bioreactor Market Share by Company
11.7.3 Massive Investments in Single-Use Bioreactors
11.8 Global Market for Microcarriers used in Cell Culture
11.9 Market for Induced Pluripotent Stem Cells
11.9.1 Toxicology Assays using iPSCs
11.10 Market for Human Mesenchymal Stem Cells (hMSCs)
11.11 Global Market for Embryonic Stem Cells
11.12 Global Market for Stem Cells
11.13 Global Market for Stem Cell Research Products
11.13.1 Leaders in Consumables and Instruments used in Stem Cell Research
12. COMPANY PROFILES
12.1 3D Biotek LLC
12.2 Abbexa Ltd.
12.4 Abeomics Inc.
12.6 Absolute Antibody Ltd.
12.7 Agilent Technologies Inc.
12.8 Alomone Labs Ltd.
12.9 AmProtein – China Inc.
12.10 Antigenix America Inc.
12.11 Apceth Biopharma GmbH
12.12.1 Cell Types Offered
12.12.2 Cell Banking & Formulation
12.13 Applikon Biotechnology BV
12.14 AS ONE INTERNATIONAL, INC.
12.17 Athersys, Inc.
12.18 Atlas Antibodies AB
12.19 ATVIO Biotech, Ltd.
12.20 Aviva Systems Biology Corp.
12.21 Becton, Dickinson and Company
12.22 Bio Basic
12.22.1 Products & Services
12.25 BioLife Solutions Inc.
22.214.171.124 Cell Thawing Media
126.96.36.199 ThawSTAR Products
12.26 Bio-Rad Laboratories, Inc.
12.27 Biorbyt Ltd.
12.28 BioSperix Ltd.
12.29 Bioss Antibodies Inc
12.30 BioVendor – Laboratorni Medicina A.S
12.30.1 Products & Services
12.31 BioVision Inc.
12.32 Bio X Cell
12.33 Bon Opus Biosciences
12.36 Cell Culture Technologies LLC
12.37 Cellexus Ltd.
12.37.1 CellMaker Bioreactors
12.38 Cell Microsystems Inc.
12.39 Cell Signaling Technology Inc.
12.40 Celltainer Biotech
12.41 ChromoTek GmbH
12.42 Cognate BioServices Inc.
12.43 Corning Life Sciences
12.44 CUSABIO Technology LLC
12.45 Cygnus Technologies
12.46 Diagenode SA
12.47 DWK Life Sciences
12.47.1 Cell Culture Products
12.48 EMD Millipore Corp.
12.49 enQuire BioReagents
12.50 Enzo Lifesciences Inc.
12.51 EpiGentek Group Inc.
12.52 Eppendorf AG
12.53 Eurogentec, S.A.
12.54 EXBIO Praha a.s
12.55 FabGennix International Inc.
12.56 Fitzgerald Industries International
12.57 GE Healthcare Bio-Sciences
12.58 GeneTex Inc.
12.60 Greiner Bio-One International GmbH
12.61 HemaCare Corporation
12.62 HiMedia Laboratories
12.64 Hycult Biotech
12.65 HyTest Ltd.
12.66 ImmuQuest Ltd.
12.67 InSphero AG
188.8.131.52 3D InSight Microtissue
12.68 Invent Biotechnologies Inc.
184.108.40.206 Minute Kits
12.70 Irvine Scientific, Inc. (FUJIFILM Irvine Scientific, Inc.)
12.71 iXCells Biotechnologies
220.127.116.11 iPSC-Derived Cells
18.104.22.168 Human Primary Cells
22.214.171.124 Cell Media & Reagents
12.72 Kerafast, Inc.
126.96.36.199 Antibodies & Secondary Detection Reagents
188.8.131.52 Buffers & Chemicals
184.108.40.206 Cell Culture & Transfection Reagents
220.127.116.11 Cell & Tissue Samples
12.73 LifeSpan BioSciences Inc.
12.74 Lonza AG
12.74.1 Products & Services
12.75 Maine Biotechnology Services (BBI Group)
12.76 MaSTherCell S.A.
12.77 MBL International
12.78 MD Biosciences (Bioproducts Division)
12.79 Miltenyi Biotec GmbH
12.80 Minerva Biotechnologies Corporation
12.81 Monash Antibody Technologies Facility (MATF)
12.82 MP Biomedicals LLC
12.83 MyBioSource Inc.
12.84 Ncardia AG
12.84.1 Solutions Offered
12.85 New England Biolabs
12.86 Novasep Holding SAS
12.88 Novus Biologicals
12.89 NSJ Bioreagents
12.91 PBS Biotech Inc.
12.93 PromoCell GmbH
12.93.1 Products & Services
12.94 ProSci Inc.
12.95 Proteintech Group Inc.
12.96.1 Products & Services
12.97 QED Bioscience Inc.
12.98 Ray Biotech
12.99 Rev MAb Biosciences
12.100 Reddot Biotech Inc
12.101 R & D Systems
12.102 REPROCELL Inc.
12.103 RoosterBio, Inc.
12.105 SAFC Biosciences Inc.
12.106 Santa Cruz Biotechnology Inc.
12.107 Sartorius AG
12.108 ScienCell Research Laboratories
18.104.22.168 Primary Cells
22.214.171.124 Cell Culture Media
126.96.36.199 Stem Cells
188.8.131.52 Other Products
12.109 Sigma-Aldrich Corp.
12.110 Signalway Antibody LLC
12.111 Sino Biological Inc.
12.112 Shanghai Korain Biotech Co., Ltd.
12.114 StemBioSys, Inc.
12.114.1 CELLvo Matrix
12.114.2 CELLvo Cells
12.115 STEMCELL Technologies.
184.108.40.206 Cell Culture Media and Supplements
220.127.116.11 Cell Isolation Products
18.104.22.168 Primary and Cultured Cells
22.214.171.124 Cell Storage Media
12.116 Synaptic Systems GmbH
12.117 Synthecon Inc.
126.96.36.199 3D Cell Culture Bioreactors – Rotary Cell Culture
12.118 Takara Bio Inc.
12.119 Terumo BCT Inc.
12.119.1 Products & Services
12.120 Thermo Fisher Scientific Inc
12.121 United States Biological
12.122 Vitrolife AB
12.123 VWR International LLC
12.124 Wuxi Donglin Sci & Tech Development Co. Ltd.
12.125 Xcellerex (GE Healthcare)
12.126 YposKesi, SAS (Genethon)
12.127 Zen-Bio, Inc.
12.128 Zellwerk GmbH
12.128.1 Z RP Technology Implant Moldings
INDEX OF FIGURES
Figure 2.1: Research Areas Using Stem Cells
Figure 2.2: Species Sources of Cells for Stem Cell Research
Figure 2.3: Disease Areas using Stem Cells for Research/Drug Discovery
Figure 10.1: Categories of Expenditure in Stem Cell Manufacturing
Figure 10.2: The Impact of Head Count on Labor Cost
Figure 10.3: Cost of Stem Cell Manufacture in a Partially-Automated Facility
Figure 10.4: Cost of Stem Cell Manufacture in a Fully-Automatic Facility
Figure 11.1: Global Market for Flow Cytometry Systems used in Cell Culture, 2019-2026
Figure 11.2: Flow Cytometry Market Share by Company
Figure 11.3: Global Market for Stem Cell Research Antibodies, 2019-2026
Figure 11.4: Stem Cell Research Antibodies Market Share by Company
Figure 11.5: Global Market for Stem Cell Assays by Geography, 2019-2026
Figure 11.6: Global Market for Stem Cell Assays by Product Segments
Figure 11.7: Global Market for Stem Cell Media by Geography, 2019-2026
Figure 11.8: Stem Cell Culture Media Market Share by Company
Figure 11.9: Global Market for Recombinant Cell Culture Supplements, 2019-2026
Figure 11.10: Global Market for Stem Cell Cryopreservation Products, 2019-2026
Figure 11.11: Market Share of Cryopreservation Products by Type, 2019
Figure 11.12: Market for SUBs in Stem Cell Culture by Geography, 2019-2026
Figure 11.13: Market for Single-Use Bioreactors in Stem Cell Culture by Product Segment
Figure 11.14: Single-Use Bioreactor Market Share by Company
Figure 11.15: Global Market for Microcarriers by Geography, 2019-2026
Figure 11.16: Global Market for Induced Pluripotent Stem Cells by Geography, 2019-2026
Figure 11.17: Relative Use of iPSC-Derived Cell Types in Toxicology Assays
Figure 11.18: Global Market for Mesenchymal Stem Cells by Geography, 2019-2026
Figure 11.19: Global Market for Embryonic Stem Cells by Geography, 2019-2026
Figure 11.20: Global Market for Stem Cells by Geography, 2019-2026
Figure 11.21: Global Market for Stem Cell Research Products by Type, 2019-2026
Figure 11.22: Major Suppliers of Consumables and Instruments in Stem Cell Research
INDEX OF TABLES
Table 3.1: Examples of Embryonic Stem Cell Markers and Antibody Suppliers
Table 3.2: Examples of Hematopoietic Stem Cell Markers and Antibody Suppliers
Table 3.3: Examples of Cancer Stem Cell Markers and Antibody Suppliers
Table 3.4: Examples of Osteoprogenitor Cell Markers and Antibody Suppliers
Table 3.5: Examples of Neural Stem Cell Markers and Antibody Suppliers
Table 3.6: Examples of Mesenchymal Stem Cell Markers and Suppliers of Antibodies
Table 3.7: Examples of Skin Stem Cell Markers and Antibody Suppliers
Table 4.1: Commercially Available Stem Cell Isolation Kits and Suppliers
Table 4.2: Commercially Available Flow Cytometry Systems
Table 5.1: Commercially Available Primary Antibodies
Table 5.2: Commercially Available Secondary Antibodies
Table 5.3: Commercially Available Recombinant Antibodies
Table 5.4: Commercially Available Trial Size Antibodies
Table 5.5: Commercially Available Apoptosis Antibodies
Table 5.6: Commercially Available Epitope Tag Antibodies
Table 5.7: Commercially Available Isotype Control Antibodies
Table 5.8: Pluripotent Stem Cell Markers Antibody Products and Suppliers
Table 5.9: Mesenchymal Stem Cell Markers Antibody Products
Table 5.10: Hematopoietic Stem Cell Markers Antibody Products
Table 5.11: Neural Stem Cell Marker Antibodies
Table 5.12: Cancer Stem Cell Marker Antibodies
Table 5.13: Companies Providing Antibody Production and Development Services
Table 5.14: Companies Providing Monoclonal Antibody Production Services
Table 5.15: Companies Offering Polyclonal Antibody Production Services
Table 5.16: Companies Offering Antibody Purification Services
Table 5.17: Companies Offering Antibody Conjugation and Labeling Services
Table 5.18: Companies Providing Hybridoma Services
Table 5.19: Companies Offering Recombinant Antibody Production Services
Table 5.20: Commercially Available Stem Cell Factor ELISA Kits and Suppliers
Table 6.1: Types of Natural and Artificial Media
Table 6.2: Cell Lines and Choice of Culture Media
Table 6.3: Recommended Media for Primary Cell Culture
Table 6.4: Companies Offering Stem Cell Culture Media
Table 6.5: Examples of Methylcellulose Media
Table 6.6: Commercially Available Stem Cell Differentiation Media
Table 6.7: Commercially Available Stem Cell Expansion Media
Table 6.8: Commercially Available Embryonic Stem Cell Media
Table 6.9: Commercially Available Hematopoietic Stem Cell Media
Table 6.10: Commercially Available Mesenchymal Stem Cell Media
Table 6.11: Commercially Available Neural Stem Cell Media
Table 6.12: Components of Media Supplements
Table 6.13: Commercially Available Cell Culture Supplements and Vendors
Table 6.14: Examples of Cell Freezing Media
Table 7.1: Bioreactors used for Stem Cell Expansion
Table 7.2: Pros and Cons of Fixed Bioreactors
Table 7.3: Pros and Cons of Single Use Bioreactors
Table 7.4: Commercially Available Liter- and Cubic Meter-Scale SUBs
Table 7.5: Main Features of Commercial Bioreactors
Table 7.6: Main Differences between Single-Use and Multi-Use Bioreactors
Table 7.7: Microcarriers used in Bioreactors
Table 8.1: Examples of Commercially Available Stem Cell Lines
Table 9.1: Select Institutional Manufacturing Facilities for Stem Cell Manufacture
Table 9.2: Select CMOs and Their Services in Stem Cell Manufacturing
Table 9.3: Select Cell Manufacturing Solutions
Table 9.4: Select Closed Manufacturing Systems
Table 10.1: Categories of Expenditure in Stem Cell Manufacturing
Table 10.2: The Impact of Head Count on Labor Cost
Table 10.3: Cost of Stem Cell Manufacture in a Partially-Automated Facility
Table 10.4: Cost of Stem Cell Manufacture in a Fully-Automatic Facility
Table 11.1: Global Market for Flow Cytometry Systems used in Cell Culture, 2019-2026
Table 11.2: Global Market for Stem Cell Research Antibodies, 2019-2026
Table 11.3: Global Market for Stem Cell Assays by Geography, 2019-2026
Table 11.4: Global Market for Stem Cell Media by Geography, 2019-2026
Table 11.5: Global Market for Recombinant Cell Culture Supplements, 2019-2026
Table 11.6: Market for Stem Cell Cryopreservation Products by Geography, 2019-2026
Table 11.7: Global Market for SUBs in Stem Cell Culture by Geography, 2019-2026
Table 11.8: Global Market for Microcarriers by Geography, 2019-2026
Table 11.9: Global Market for iPSCs by Geography, 2019-2026
Table 11.10: Global Market for Mesenchymal Stem Cells by Geography, 2019-2026
Table 11.11: Global Market for Embryonic Stem Cells by Geography, 2019-2026
Table 11.12: Global Market for Stem Cells by Cell Type, 2019-2026
Table 11.13: Global Market for Stem Cell Research Products, 2019-2026
Table 11.14: Major Suppliers of Consumables and Instruments in Stem Cell Research
- Thermo Fisher Scientific
- STEMCELL Technologies
- FUJIFILM CDI
- Miltenyi Biotec
- Merck KGaA
- Lonza Group
- Abbexa Ltd.
- Abeomics Inc.
- Absolute Antibody Ltd.
- Agilent Technologies Inc.
- Alomone Labs Ltd.
- AmProtein – China Inc.
- Antigenix America Inc.
- Apceth Biopharma GmbH
- Applikon Biotechnology BV
- AS ONE INTERNATIONAL, INC.
- Athersys, Inc.
- Atlas Antibodies AB
- ATVIO Biotech, Ltd.
- Aviva Systems Biology Corp.
- BD Biosciences, a Division of Becton Dickinson (BD)
- Becton, Dickinson and Company
- Bio Basic
- Bio X Cell
- BioLife Solutions Inc.
- Bio-Rad Laboratories, Inc.
- Biorbyt Ltd.
- BioSperix Ltd.
- Bioss Antibodies Inc
- BioVendor – Laboratorni Medicina A.S
- BioVision Inc.
- Bon Opus Biosciences
- Cell Culture Technologies LLC
- Cell Microsystems Inc.
- Cell Signaling Technology Inc.
- Cellexus Ltd.
- Celltainer Biotech
- ChromoTek GmbH
- Cognate BioServices Inc.
- Corning Life Sciences
- CUSABIO Technology LLC
- Diagenode SA
- DWK Life Sciences
- EMD Millipore Corp.
- enQuire BioReagents
- Enzo Lifesciences Inc.
- EpiGentek Group Inc.
- Eppendorf AG
- Eurogentec, S.A.
- EXBIO Praha a.s
- FabGennix International Inc.
- Fitzgerald Industries International
- Cygnus Technologies
- GE Healthcare Bio-Sciences
- GeneTex Inc.
- Greiner Bio-One International GmbH
- HemaCare Corporation
- Highwire Press
- HiMedia Laboratories
- HyTest Ltd.
- ImmuQuest Ltd.
- InSphero AG
- Invent Biotechnologies Inc.
- Irvine Scientific, Inc. (FUJIFILM Irvine Scientific, Inc.)
- iXCells Biotechnologies
- Kerafast, Inc.
- Kyoto University
- LifeSpan BioSciences Inc.
- SAFC Biosciences Inc.
- Maine Biotechnology Services (BBI Group)
- MaSTherCell S.A.
- MBL International
- MD Biosciences (Bioproducts Division)
- Hycult Biotech
- Minerva Biotechnologies Corporation
- Monash Antibody Technologies Facility (MATF)
- MP Biomedicals LLC
- MyBioSource Inc.
- Ncardia AG
- New England Biolabs
- Novasep Holding SAS
- Novus Biologicals
- NSJ Bioreagents
- PBS Biotech Inc.
- PromoCell GmbH
- ProSci Inc.
- Proteintech Group Inc.
- QED Bioscience Inc.
- R & D Systems
- Ray Biotech
- Reddot Biotech Inc
- REPROCELL Inc.
- Rev MAb Bioscience
- RoosterBio, Inc.
- Santa Cruz Biotechnology Inc.
- Sartorius AG
- ScienCell Research Laboratories
- Shanghai Korain Biotech Co., Ltd.
- Sigma-Aldrich Corp.
- Signalway Antibody LLC
- Sino Biological Inc.
- StemBioSys, Inc.
- Synaptic Systems GmbH
- Synthecon Inc.
- Takara Bio Inc.
- Terumo BCT Inc.
- 3D Biotek LLC
- United States Biological
- United States Patent and Trade Office
- University of Wisconsin-Madison
- Vitrolife AB
- VWR International LLC
- Wellcome Trust
- World Intellectual Property Organization
- Wuxi Donglin Sci & Tech Development Co. Ltd.
- Xcellerex (GE Healthcare)
- YposKesi, SAS (Genethon)
- Zellwerk GmbH
- Zen-Bio, Inc.
The content and statistics contained within the publisher's reports are compiled using a broad range of sources, as described below.
- Clinical Trial Databases (ClinicalTrials.gov, International Clinical Trials Registry Platform, European Union Clinical Trials Register, Chinese Clinical Trial Registry, Others)
- Scientific Publication Databases (PubMed, Highwire Press, Google Scholar)
- Patent Databases (United States Patent and Trade Office, World Intellectual Property Organization, Google Patent Search)
- Grant Funding Databases (RePORT Database, CIRM, MRC, Wellcome Trust - UK, Others)
- Product Launch Announcements (Trade Journals, Google News)
- Industry Events (Google News, Google Alerts, Press Releases)
- Company News (SEC Filings, Investor Publications, Historical Performance)
- Social Analytics (Google Adwords, Google Trends, Twitter, Topsy.com, Hashtagify.me, BuzzSumo.com)
- Interviews with Stem Cell Industry Leaders
Research & Analysis Methodologies
The publisher employs the following techniques for deriving its market research:
- Historical Databases: As the first and only market research firm to specialize in the stem cell industry, the publisher has 13+ years of historical data on each segment of the stem cell the industry. This provides an extremely rare and robust database for establishing market size determinations, as well as making future market predictions.
- Prolific Interviews with Industry Leaders: As the global leader in stem cell industry data, the publisher has interviewed hundreds of leaders from across the stem cell industry, including the CEO of FUJIFILM CDI, FUJIFILM Irvine Scientific, Pluristem Therapies, Celularity, and many others.
- Industry Relationships: The research team and its President/Founder, Cade Hildreth, Chair and present at a wide range of stem cell industry events, including Phacilitate's Advanced Therapies Week, World Stem Cell Summit (WSCS), Perinatal Stem Cell Society Congress, AABB's International Cord Blood Symposium (ICBS), and other events hosted within the U.S. and worldwide.
- Global Integrated Feedback: Because the publisher maintains the world's largest stem cell industry news site that is read by nearly a million unique readers per year and the company has large social media audiences (25.7K+ followers on Linked, 21.2K+ followers on Twitter, and 4.3K+ followers on Facebook), the publisher is able to publish content relevant to the industry and receive immediate feedback/input from a global community of readers. In short, the publisher's data is crowd-sourced from market participants worldwide, including those in diverse geographic regions.
- Preliminary Research: In addition to the interviews described above, the publisher conducts market surveys, executes social media polls, and aggregates market data from stem cell industry announcements, press releases, and corporate filings/presentations.
- Secondary Research: The publisher summarizes, collects and synthesizes existing market research that is relevant to the market area of interest.
- Future Projections: Using the resources described above, the publisher is uniquely positioned to make future projections about market size, market growth by segment, market trends, technology evolution, funding activities (financing rounds, M&A, and IPOs), and importantly, market leadership (market share by company).