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Interleukin 1 - Pipeline Review, H2 2020

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    Drug Pipelines

  • 156 Pages
  • July 2020
  • Region: Global
  • Global Markets Direct
  • ID: 5137233
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Interleukin 1 - Pipeline Review, H2 2020

Summary

Interleukin 1 (IL1) pipeline Target constitutes close to 30 molecules. Out of which approximately 29 molecules are developed by companies and remaining by the universities/institutes. The latest report Interleukin 1 - Pipeline Review, H2 2020, outlays comprehensive information on the Interleukin 1 (IL1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.

Interleukin 1 (IL1) - Interleukin-1 is a cytokine which plays an important role regulation of immune and inflammatory responses. It helps leukocytes pass through blood vessel walls to sites of infection and causes fever by affecting areas of the brain that control body temperature. There are two forms of interleukin-1, alpha and beta. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical and Discovery stages are 4, 6, 3, 13 and 3 respectively. Similarly, the universities portfolio in Preclinical stages comprises 1 molecules, respectively.

Report covers products from therapy areas Immunology, Cardiovascular, Oncology, Gastrointestinal, Infectious Disease, Musculoskeletal Disorders, Dermatology, Genetic Disorders, Metabolic Disorders, Respiratory, Central Nervous System, Hematological Disorders, Ear Nose Throat Disorders and Genito Urinary System And Sex Hormones which include indications Coronavirus Disease 2019 (COVID-19), Gouty Arthritis (Gout), Inflammation, Non-Small Cell Lung Cancer, Atopic Dermatitis (Atopic Eczema), Autoimmune Disorders, Behcet Disease, Colorectal Cancer, Epidermolysis Bullosa, Esophageal Cancer, Familial Mediterranean Fever, Metastatic Melanoma, Muckle-Wells Syndrome, Myocardial Infarction, Prostate Cancer, Renal Cell Carcinoma, Rheumatoid Arthritis, Sickle Cell Disease, Triple-Negative Breast Cancer (TNBC), Acne Vulgaris, Acute Respiratory Distress Syndrome, Alcoholic Hepatitis, Allergic Rhinitis, Alzheimer's Disease, Atherosclerosis, Bile Duct Cancer (Cholangiocarcinoma), Bladder Cancer, Brain Cancer, Cancer Pain, Cardiovascular Risk Factors, Cervical Cancer, Cholangitis, Crohn's Disease (Regional Enteritis), Cytokine Release Syndrome (Cytokine Storm), Diffuse Large B-Cell Lymphoma, Endometrial Cancer, Fallopian Tube Cancer, Familial Cold Autoinflammatory Syndrome (Familial Cold Urticaria), Follicular Lymphoma, Gastric Cancer, Glioblastoma Multiforme (GBM), Head And Neck Cancer, Head And Neck Cancer Squamous Cell Carcinoma, Hearing Disorders, Hemorrhagic Shock, Hidradenitis Suppurativa, Inflammatory Bowel Disease, Inflammatory Pain, Kidney Cancer (Renal Cell Cancer), Kidney Fibrosis, Limited/Distal Colitis, Liver Fibrosis, Lung Cancer, Lymphoma, Metastatic Breast Cancer, Metastatic Colorectal Cancer, Metastatic Ovarian Cancer, Metastatic Prostate Cancer, Metastatic Renal Cell Carcinoma, Multiple Myeloma (Kahler Disease), Multiple Sclerosis, Neonatal Onset Multisystem Inflammatory Disease, Neuropathic Pain (Neuralgia), Osteoarthritis, Osteosarcoma, Ovarian Cancer, Pericarditis, Pneumonia, Psoriasis, Recurrent Glioblastoma Multiforme (GBM), Sarcoidosis, Schnitzler Syndrome, Seizures, Soft Tissue Sarcoma, Squamous Non-Small Cell Lung Cancer, Stroke, Systemic Juvenile Rheumatoid Arthritis, Transitional Cell Cancer (Urothelial Cell Cancer), Traumatic Brain Injury and Type 2 Diabetes.

Furthermore, this report also reviews key players involved in Interleukin 1 (IL1) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope
  • The report provides a snapshot of the global therapeutic landscape for Interleukin 1 (IL1)
  • The report reviews Interleukin 1 (IL1) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in Interleukin 1 (IL1) targeted therapeutics and enlists all their major and minor projects
  • The report assesses Interleukin 1 (IL1) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews latest news and deals related to Interleukin 1 (IL1) targeted therapeutics

Reasons to Buy
  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for Interleukin 1 (IL1)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding Interleukin 1 (IL1) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Table of Contents

IntroductionInterleukin 1 (IL1) - OverviewInterleukin 1 (IL1) - Therapeutics DevelopmentInterleukin 1 (IL1) - Therapeutics AssessmentInterleukin 1 (IL1) - Companies Involved in Therapeutics Development
Interleukin 1 (IL1) - Drug Profiles
  • Interleukin 1 (IL1) - Dormant Products

Interleukin 1 (IL1) - Discontinued ProductsInterleukin 1 (IL1) - Product Development MilestonesAppendix
List of Tables
  • Number of Products under Development by Stage of Development, H2 2020
  • Number of Products under Development by Therapy Areas, H2 2020
  • Number of Products under Development by Indications, H2 2020
  • Number of Products under Development by Companies, H2 2020
  • Number of Products under Development by Companies, H2 2020 (Contd..1)
  • Products under Development by Companies, H2 2020
  • Number of Products under Investigation by Universities/Institutes, H2 2020
  • Products under Investigation by Universities/Institutes, H2 2020
  • Number of Products by Stage and Mechanism of Actions, H2 2020
  • Number of Products by Stage and Route of Administration, H2 2020
  • Number of Products by Stage and Molecule Type, H2 2020
  • Pipeline by 3SBio Inc, H2 2020
  • Pipeline by Akeso Inc, H2 2020
  • Pipeline by Bioiberica SAU, H2 2020
  • Pipeline by Devonian Health Group Inc, H2 2020
  • Dormant Products, H2 2020
  • Discontinued Products, H2 2020

List of Figures
  • Number of Products under Development by Stage of Development, H2 2020
  • Number of Products under Development by Therapy Areas, H2 2020
  • Number of Products under Development by Top 10 Indications, H2 2020
  • Number of Products by Mechanism of Actions, H2 2020
  • Number of Products by Stage and Mechanism of Actions, H2 2020
  • Number of Products by Routes of Administration, H2 2020
  • Number of Products by Stage and Routes of Administration, H2 2020
  • Number of Products by Molecule Types, H2 2020
  • Number of Products by Stage and Molecule Types, H2 2020

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • 3SBio Inc
  • Akeso Inc
  • Bioiberica SAU
  • Devonian Health Group Inc
  • Flame Biosciences Inc
  • ImmunoChem Therapeutics LLC
  • Johnson & Johnson
  • Komipharm International Co Ltd
  • Link Health Group
  • Mabpharm Ltd
  • Moderna Inc
  • Novartis AG
  • Omnitura Therapeutics Inc
  • Opsona Therapeutics Ltd
  • Peptinov SAS
  • R Pharm
  • Regeneron Pharmaceuticals Inc
  • Spherium Biomed SL
  • Swedish Orphan Biovitrum AB
  • Therapicon Srl
  • ThioLab LLC
  • TWi Biotechnology Inc
  • XBiotech Inc